General information for g16141.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha.
Parent gene
- The parent gene g16141 is located on chr_4: 8355682..8356891 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16141 | g16141.t3 | TSS | g16141.t3 | 8352553 | 8352553 |
| chr_4 | g16141 | g16141.t3 | isoform | g16141.t3 | 8352632 | 8356285 |
| chr_4 | g16141 | g16141.t3 | exon | g16141.t3.exon1 | 8352632 | 8352643 |
| chr_4 | g16141 | g16141.t3 | exon | g16141.t3.exon2 | 8354666 | 8354960 |
| chr_4 | g16141 | g16141.t3 | cds | g16141.t3.CDS1 | 8354740 | 8354960 |
| chr_4 | g16141 | g16141.t3 | exon | g16141.t3.exon3 | 8355017 | 8355397 |
| chr_4 | g16141 | g16141.t3 | cds | g16141.t3.CDS2 | 8355017 | 8355397 |
| chr_4 | g16141 | g16141.t3 | exon | g16141.t3.exon4 | 8355453 | 8355621 |
| chr_4 | g16141 | g16141.t3 | cds | g16141.t3.CDS3 | 8355453 | 8355621 |
| chr_4 | g16141 | g16141.t3 | exon | g16141.t3.exon5 | 8355681 | 8355835 |
| chr_4 | g16141 | g16141.t3 | cds | g16141.t3.CDS4 | 8355681 | 8355835 |
| chr_4 | g16141 | g16141.t3 | exon | g16141.t3.exon6 | 8355892 | 8355983 |
| chr_4 | g16141 | g16141.t3 | cds | g16141.t3.CDS5 | 8355892 | 8355983 |
| chr_4 | g16141 | g16141.t3 | exon | g16141.t3.exon7 | 8356041 | 8356105 |
| chr_4 | g16141 | g16141.t3 | cds | g16141.t3.CDS6 | 8356041 | 8356105 |
| chr_4 | g16141 | g16141.t3 | exon | g16141.t3.exon8 | 8356170 | 8356285 |
| chr_4 | g16141 | g16141.t3 | cds | g16141.t3.CDS7 | 8356170 | 8356190 |
| chr_4 | g16141 | g16141.t3 | TTS | g16141.t3 | 8357268 | 8357268 |
Sequences
>g16141.t3 Gene=g16141 Length=1285
GTTGTTAATTAGGTTCAAAAAATAAAGAGAAGAAATTTTCTCTTATCAATTTCTTCTCAA
AAGTTAGTCAAAACACACAGAAAAAAATGACAACGCCAGCAGCGAGAATCCTTAAAAAGA
AGCACTTTCGCGTAAAGCATCAAAAGGTCAAATTATTTCGTGCAAATGAGCCTCTACTGA
GCGTATTCATGTGGGGCGTTAATCACACAATTAACGAATTGTCACATGTAAACATTCCCG
GCTTGCTCTTGCCAGATCATTTTCGTGCTCATTCAAAAATTAAAGTTGACTATCATTTAT
TCAATAAAGAAAACATGCCATCACATTTTAAATTTAAAGAATATTGTCCACTTGTGTTCA
AATATTTACGTGAACGATTTGGAATCGATGACATTGAATATCGTGAATCATTGACACGTT
CACAACCAACCTTTACAGATGATCGTGGTAAATCGGGAGCCAAATTTTACCTGAGCTACG
ATAAAATGTTCATTATTAAGTCACTAACGAGTGAGGAAGTTGAGCGAATGCATTCATTCC
TTAAACATTATCATCCATATGTGGTTGAAAAACATGGAAATACACTCCTGCCACAATATT
TGGGAATGTATAGGCTGACGTTAGATGGTGTGCAGTATTACTTTAAAGTTATGAGGAATG
TGTTCAGTCCACATTTTAGGATTCATCAGAAATTTGACCTCAAAGGTTCAACAGTCGATC
GTGAAGCATCCGACAAAGAACTTGACAAATCGTTACCAACACTCAAAGACAATGATTTCA
TTAAACAGGGCATCAGAATTAAAATTGGTCCAGAGGCTAAAGAAAAATTCAATGCAACAC
TCACTGCTGATGTTGAATTCCTATTAAAACTTCATTTAATGGATTATTCATTACTGATTG
GTATTCATGATGTGCGGCAAGCAGCAGAAGATGCTGAAGCACGTGGTGATGGAAATCGAA
GTGATCCACATCATGACAGTGAAAGTGAAAATGAATATGATAGTGGAGAAAGATGGGAAA
ATACACCACCAGATTCACCTCGTCAAGCTGATGCTCATGTTATAAATCCAGACATTGACG
TTTATGCTGTTGCAAGTCAAGAAGAAAATCAATTTATTTATTTCATGGCGATAATTGATC
CATTGACGAATTATGGATTAAAAAAACAACCAAAGCAGCAAAGACAGTGAAATATGGAAG
CAATGTTGATGGAATAAGCACCTGTGATCCGGAACAGTACGCCAAGCGATTCCTTGAGTT
CATAAATGATAAAGTCATTGAATAA
>g16141.t3 Gene=g16141 Length=367
MTTPAARILKKKHFRVKHQKVKLFRANEPLLSVFMWGVNHTINELSHVNIPGLLLPDHFR
AHSKIKVDYHLFNKENMPSHFKFKEYCPLVFKYLRERFGIDDIEYRESLTRSQPTFTDDR
GKSGAKFYLSYDKMFIIKSLTSEEVERMHSFLKHYHPYVVEKHGNTLLPQYLGMYRLTLD
GVQYYFKVMRNVFSPHFRIHQKFDLKGSTVDREASDKELDKSLPTLKDNDFIKQGIRIKI
GPEAKEKFNATLTADVEFLLKLHLMDYSLLIGIHDVRQAAEDAEARGDGNRSDPHHDSES
ENEYDSGERWENTPPDSPRQADAHVINPDIDVYAVASQEENQFIYFMAIIDPLTNYGLKK
QPKQQRQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g16141.t3 | CDD | cd17305 | PIPKc_PIP5KII | 29 | 361 | 4.48167E-169 |
| 6 | g16141.t3 | Gene3D | G3DSA:3.30.800.10 | Phosphatidylinositol Phosphate Kinase II Beta | 12 | 191 | 2.8E-67 |
| 5 | g16141.t3 | Gene3D | G3DSA:3.30.810.10 | - | 192 | 365 | 4.0E-41 |
| 9 | g16141.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 282 | 319 | - |
| 10 | g16141.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 282 | 312 | - |
| 2 | g16141.t3 | PANTHER | PTHR23086:SF21 | PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA | 9 | 361 | 1.4E-131 |
| 3 | g16141.t3 | PANTHER | PTHR23086 | PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE | 9 | 361 | 1.4E-131 |
| 1 | g16141.t3 | Pfam | PF01504 | Phosphatidylinositol-4-phosphate 5-Kinase | 119 | 361 | 7.9E-63 |
| 11 | g16141.t3 | ProSiteProfiles | PS51455 | Phosphatidylinositol phosphate kinase (PIPK) domain profile. | 26 | 367 | 56.883 |
| 8 | g16141.t3 | SMART | SM00330 | PIPK_2 | 55 | 364 | 1.2E-73 |
| 4 | g16141.t3 | SUPERFAMILY | SSF56104 | SAICAR synthase-like | 24 | 362 | 1.77E-98 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016307 | phosphatidylinositol phosphate kinase activity | MF |
| GO:0046488 | phosphatidylinositol metabolic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
