Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Glutathione S-transferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g16419 g16419.t56 TTS g16419.t56 9392821 9392821
chr_4 g16419 g16419.t56 isoform g16419.t56 9392882 9395632
chr_4 g16419 g16419.t56 exon g16419.t56.exon1 9392882 9393198
chr_4 g16419 g16419.t56 cds g16419.t56.CDS1 9392882 9393198
chr_4 g16419 g16419.t56 exon g16419.t56.exon2 9394140 9394307
chr_4 g16419 g16419.t56 cds g16419.t56.CDS2 9394140 9394307
chr_4 g16419 g16419.t56 exon g16419.t56.exon3 9395162 9395293
chr_4 g16419 g16419.t56 cds g16419.t56.CDS3 9395162 9395231
chr_4 g16419 g16419.t56 exon g16419.t56.exon4 9395496 9395632
chr_4 g16419 g16419.t56 TSS g16419.t56 9395732 9395732

Sequences

>g16419.t56 Gene=g16419 Length=754
ATGGTGGTTTACAAATTACATTATTTTAATTTAACTGGTTTGGGTGAACCGATTCGATTT
TTATTCCATTATGGTGGAATTGATTTTGAAGATGTGAGGTATGAAATGAATGAATGGGTC
GATCTTAAAAAAAGTAAAATGAATTACCTGTAAATTTCACAATTTATAGAAAATTGAAAA
CTACCGAGATATTTCTTGAATGAAGAAATATAATAAGACTGAAGCGTTGATGCAAGCGTT
GTTTACGCTTTATAAACAAGAAACTGAGAAATTCCCTCTTGGTCAATTACCAGTCTTAGA
AATAGACGACAAAGAGCATGTTCAATCAATGGCAATTTGTCGCTATTTAGCAAAACAAGT
CGGTCTTGCTGGAGACAGTGACCTTGAAAACATGGAAATTGATGCGGTTGTTGATACTTT
CAATGATATTCGTCTTAAAATTTCAACTGTGATGTGGGAACAAAATCAGGAAGTAAAAAA
AGAGAAACAAAAAATTCTACACGAGCAGCAAATTCCATTTTATTTTAAGAAGCTTGATGA
ATATGCCGAAGCCAATAATGGACATTTTGCATGTAAAAAATTAACTTGGGCTGACTTGTA
CATCGCATCTTGGTCAAAGTATTTCTCTTATGCCATCAAAGAAGTCTTCAATGATTATGA
AAACTATCCAAACATTAAGAAAGTTGTCGACAATGTTTTAGCAATTGAAAACATTAAAAA
ATGGGTTGAAACAAGACCCGACACATTCTGTTGA

>g16419.t56 Gene=g16419 Length=184
MKKYNKTEALMQALFTLYKQETEKFPLGQLPVLEIDDKEHVQSMAICRYLAKQVGLAGDS
DLENMEIDAVVDTFNDIRLKISTVMWEQNQEVKKEKQKILHEQQIPFYFKKLDEYAEANN
GHFACKKLTWADLYIASWSKYFSYAIKEVFNDYENYPNIKKVVDNVLAIENIKKWVETRP
DTFC

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g16419.t56 CDD cd03192 GST_C_Sigma_like 63 166 0.0000000
8 g16419.t56 Gene3D G3DSA:3.40.30.10 Glutaredoxin 2 55 0.0000000
7 g16419.t56 Gene3D G3DSA:1.20.1050.10 - 56 168 0.0000000
3 g16419.t56 PANTHER PTHR11571:SF234 GLUTATHIONE S-TRANSFERASE S1 22 182 0.0000000
4 g16419.t56 PANTHER PTHR11571 GLUTATHIONE S-TRANSFERASE 22 182 0.0000000
1 g16419.t56 Pfam PF02798 Glutathione S-transferase, N-terminal domain 23 51 0.0000061
2 g16419.t56 Pfam PF14497 Glutathione S-transferase, C-terminal domain 75 179 0.0000000
10 g16419.t56 ProSiteProfiles PS50404 Soluble glutathione S-transferase N-terminal domain profile. 1 58 16.4300000
9 g16419.t56 ProSiteProfiles PS50405 Soluble glutathione S-transferase C-terminal domain profile. 60 184 17.5010000
12 g16419.t56 SFLD SFLDS00019 Glutathione Transferase (cytosolic) 23 168 0.0000000
5 g16419.t56 SUPERFAMILY SSF52833 Thioredoxin-like 22 54 0.0000000
6 g16419.t56 SUPERFAMILY SSF47616 GST C-terminal domain-like 56 182 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006749 glutathione metabolic process BP
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values