General information for g16587.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Ubiquinone biosynthesis O-methyltransferase.
Parent gene
- The parent gene g16587 is located on chr_4: 10102672..10106307 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16587 | g16587.t1 | TTS | g16587.t1 | 10102642 | 10102642 |
| chr_4 | g16587 | g16587.t1 | isoform | g16587.t1 | 10102672 | 10103410 |
| chr_4 | g16587 | g16587.t1 | exon | g16587.t1.exon1 | 10102672 | 10103163 |
| chr_4 | g16587 | g16587.t1 | cds | g16587.t1.CDS1 | 10102672 | 10103163 |
| chr_4 | g16587 | g16587.t1 | exon | g16587.t1.exon2 | 10103213 | 10103410 |
| chr_4 | g16587 | g16587.t1 | cds | g16587.t1.CDS2 | 10103213 | 10103410 |
| chr_4 | g16587 | g16587.t1 | TSS | g16587.t1 | 10103447 | 10103447 |
Sequences
>g16587.t1 Gene=g16587 Length=690
ATGTCAAGTGTTGATATTCGTGAAATAGAAAAGTATACAAAACGAGCAAAAATTTGGTGG
GACTTGAATGGTCCTCAAATGCTTTTGCACAAACATACTCCTGCTATAAGAATTCCTTTC
ATCATTCATGGACTTTCATCAACTGGAAAAATTAAAAACAACAACAAAAATCTTCTGCAA
GGCTTAAAAATTCTCGATGCTGAAGTTACTGGAGTTGATCCAGCGCCTGCTTTAATTGAT
GTCGCAAATGAGCACTTAAAAATTCATGAAAATCTCAAAATTGAATACATTTGTGACACA
ATTGAAGGTTATAGCGTTAATAATCGACAAAAATTTGATGCTGTCATATGTTGTGAAGTT
CTCGAGCATGTCGCTGATGTCCGATCAGTTTTGAAGTCAAGTGTGGAAACTTTGAAACCA
GGCGGAAGTATTTTTGTGACAACTTTTAATAAAACAATTTTTTCATTCTTTTGGGCAATT
ATTTTTATGGAAATGATTTGTGGAATTATTCCTAGAGGTGCACATAAATGGTCAATGTTT
ATTTCACCTGAAGATGTTAGTAAAATTCTTGAAGATTATAATTGTGAGACTGTGGAAGTT
AGAGGAGCTTGGTACAGTCTTTTTAAAAAACAATGGAATGAGTCAAAATATAAAGATGTT
TTTTATGGACTGCATGCTGTTAAAAAATAA
>g16587.t1 Gene=g16587 Length=229
MSSVDIREIEKYTKRAKIWWDLNGPQMLLHKHTPAIRIPFIIHGLSSTGKIKNNNKNLLQ
GLKILDAEVTGVDPAPALIDVANEHLKIHENLKIEYICDTIEGYSVNNRQKFDAVICCEV
LEHVADVRSVLKSSVETLKPGGSIFVTTFNKTIFSFFWAIIFMEMICGIIPRGAHKWSMF
ISPEDVSKILEDYNCETVEVRGAWYSLFKKQWNESKYKDVFYGLHAVKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g16587.t1 | CDD | cd02440 | AdoMet_MTases | 62 | 149 | 1.10696E-10 |
| 7 | g16587.t1 | Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 | 8 | 229 | 4.0E-45 |
| 2 | g16587.t1 | PANTHER | PTHR43464 | METHYLTRANSFERASE | 2 | 52 | 3.0E-40 |
| 4 | g16587.t1 | PANTHER | PTHR43464:SF25 | UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL | 2 | 52 | 3.0E-40 |
| 3 | g16587.t1 | PANTHER | PTHR43464 | METHYLTRANSFERASE | 66 | 220 | 3.0E-40 |
| 5 | g16587.t1 | PANTHER | PTHR43464:SF25 | UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL | 66 | 220 | 3.0E-40 |
| 1 | g16587.t1 | Pfam | PF13489 | Methyltransferase domain | 67 | 199 | 1.0E-13 |
| 9 | g16587.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 152 | - |
| 10 | g16587.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 153 | 171 | - |
| 8 | g16587.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 172 | 229 | - |
| 6 | g16587.t1 | SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases | 10 | 227 | 1.32E-29 |
| 13 | g16587.t1 | TIGRFAM | TIGR01983 | UbiG: 3-demethylubiquinone-9 3-O-methyltransferase | 8 | 222 | 9.3E-51 |
| 12 | g16587.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 153 | 175 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008425 | 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity | MF |
| GO:0006744 | ubiquinone biosynthetic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed