General information for g16655.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Esterase FE4.
Parent gene
- The parent gene g16655 is located on chr_4: 10416601..10419076 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g16655 | g16655.t1 | isoform | g16655.t1 | 10416601 | 10419076 |
| chr_4 | g16655 | g16655.t1 | exon | g16655.t1.exon1 | 10416601 | 10416954 |
| chr_4 | g16655 | g16655.t1 | cds | g16655.t1.CDS1 | 10416601 | 10416954 |
| chr_4 | g16655 | g16655.t1 | exon | g16655.t1.exon2 | 10417010 | 10417066 |
| chr_4 | g16655 | g16655.t1 | cds | g16655.t1.CDS2 | 10417010 | 10417066 |
| chr_4 | g16655 | g16655.t1 | exon | g16655.t1.exon3 | 10417130 | 10417373 |
| chr_4 | g16655 | g16655.t1 | cds | g16655.t1.CDS3 | 10417130 | 10417373 |
| chr_4 | g16655 | g16655.t1 | exon | g16655.t1.exon4 | 10417426 | 10417676 |
| chr_4 | g16655 | g16655.t1 | cds | g16655.t1.CDS4 | 10417426 | 10417676 |
| chr_4 | g16655 | g16655.t1 | exon | g16655.t1.exon5 | 10417812 | 10417971 |
| chr_4 | g16655 | g16655.t1 | cds | g16655.t1.CDS5 | 10417812 | 10417971 |
| chr_4 | g16655 | g16655.t1 | exon | g16655.t1.exon6 | 10418137 | 10418315 |
| chr_4 | g16655 | g16655.t1 | cds | g16655.t1.CDS6 | 10418137 | 10418315 |
| chr_4 | g16655 | g16655.t1 | exon | g16655.t1.exon7 | 10418417 | 10418712 |
| chr_4 | g16655 | g16655.t1 | cds | g16655.t1.CDS7 | 10418417 | 10418712 |
| chr_4 | g16655 | g16655.t1 | TSS | g16655.t1 | 10418509 | 10418509 |
| chr_4 | g16655 | g16655.t1 | exon | g16655.t1.exon8 | 10418848 | 10419076 |
| chr_4 | g16655 | g16655.t1 | cds | g16655.t1.CDS8 | 10418848 | 10419076 |
| chr_4 | g16655 | g16655.t1 | TTS | g16655.t1 | 10419159 | 10419159 |
Sequences
>g16655.t1 Gene=g16655 Length=1770
ATGAATTTTTTGGCTTTTTTTTTATTTCTCTTCATTTGTTTATTAAATTATTCAAATGCA
AGAACATCAGAAAGTTTAAAAGTACGAATTGATGATGGAAGAATAGTTGGACGATGGATG
ACATCACTTTCAGGCCGAGATATTAGAGCTTTTATGGGAATTCCTTATGCTGCACCTCCA
ATCGGTGATTTACGATTTAAAGTACCACAAAAAGTCAAACCATGGGGAAAATTGAATTTA
TTAGCTCATAATGAACCACCAATGTGCACTCAAACAAATATTTTTGGTGATTTGACAGCT
CGTATTGTCACAGGTCAAGAAGATTGTTTATATTTAAATGTCTACACTCCAGAGATAAGT
GATGATAAGAAAGCTAAGAAGTGGCCAGTTCTTGTTTGGTTGCATGGTGGAGGATGGGTT
GTCGGTCATAGTGGATATACACAATATGGACCTGAATATTTACTTGAGCATGACATTGTG
CTTGTCACAGGAAATTATCGACTTGGTCCACTTGGATTTTTATCAACAGAAGATGAGCAT
GCTTCAGGTAATTTTGGCTTTAAAGATCAACTGGCAATGCTCGAATGGGTTCAAATGAAT
ATTGAAAAGTTTGGTGGTGATCCAAATTCTGTGACAATTTTTGGTGAAAGTGCAGGAGGT
GCAGCTGTAAATTATCACATGTTTTCATCAATGTCTCGTGGATTATTTCATCGAGCAATT
TCACAATCGGGTACACTTTTGACACCTTGGGCAGGTCCATCAGCAAAAGGACAAGCAAAA
ATGAATGCGATTAGATTAGCTGATAAAATGAATTGTTCAATTTCTGGTACAACAATGAAA
GAAATTGTTACATGTTTAAGAGGAGTTCCAGCTGAAAATATTACACTTGCTATCTATGAT
TTCTTTGAATGGGATAATGATCCAATTATTACCTTTCAACCTGTTGTTGAAGAATCAGAA
TTAGAAGAAGAACCTTTCATCATGGATTTACGATATAAAAAATTCTCATTAGATATTCCA
TGGATGGTTGGCATTACGAGTGAAGAAGGACTTTTTAAAAGTGCTTCAATTTTTAATTCA
CAAGAAAAAACAAATGATCTAATTAAAAATTGGGAAAAAATTTTACCAGCTACTTTATTT
TATGAACATCTTCATGAAGACGAAATTTTAGAGTTGAATGTTAAAATTTATGACTTTTAT
TTCAAAGAAGAATTCTTAGGCAATAGCAAAGGAAATTTGACTAATATGTGGACAGATGGA
CTTCTCGGTGGAATGTTTGACAATCTTGCTTACAGACTGCGCAATAACAACCGTGATAAC
ACTTTTGTTTATTTATTCACTCACAAAGGAGCTGCTAGTTATTCTGAATTATTCAAAGGA
GGCAGAGAAAAGTTTTATGGAACTTGTCATGCTGATGACTTAATTTATCTTTTTCCTATG
CAAAAATATAATCTTGCTCTTGCTAATTCTAAACCAACTGAAGAAGATAAAAAATTAATT
CAAATTATGACAAAAATGTGGGTTAATTTTGCATCTACTGGTACTCCAACTCCAGAATGG
ACCAAAGATTCAGAATTTCCTTTTTGGACTCCAGCTTCAAAATTTCCACTCGATTACATG
CAAATTGGAAATGAAAATGGTTTAAGCAAAAAATTATTGCAAATGAAGAAAAATTTGTAT
CCTGAAAGAGTAAGATTTTGGACGGAATTAAGAGAAAAGTTTGCATTGCATAATTGGAAA
CTTGAGACAACTGAAAAAGATGAATTGTAG
>g16655.t1 Gene=g16655 Length=589
MNFLAFFLFLFICLLNYSNARTSESLKVRIDDGRIVGRWMTSLSGRDIRAFMGIPYAAPP
IGDLRFKVPQKVKPWGKLNLLAHNEPPMCTQTNIFGDLTARIVTGQEDCLYLNVYTPEIS
DDKKAKKWPVLVWLHGGGWVVGHSGYTQYGPEYLLEHDIVLVTGNYRLGPLGFLSTEDEH
ASGNFGFKDQLAMLEWVQMNIEKFGGDPNSVTIFGESAGGAAVNYHMFSSMSRGLFHRAI
SQSGTLLTPWAGPSAKGQAKMNAIRLADKMNCSISGTTMKEIVTCLRGVPAENITLAIYD
FFEWDNDPIITFQPVVEESELEEEPFIMDLRYKKFSLDIPWMVGITSEEGLFKSASIFNS
QEKTNDLIKNWEKILPATLFYEHLHEDEILELNVKIYDFYFKEEFLGNSKGNLTNMWTDG
LLGGMFDNLAYRLRNNNRDNTFVYLFTHKGAASYSELFKGGREKFYGTCHADDLIYLFPM
QKYNLALANSKPTEEDKKLIQIMTKMWVNFASTGTPTPEWTKDSEFPFWTPASKFPLDYM
QIGNENGLSKKLLQMKKNLYPERVRFWTELREKFALHNWKLETTEKDEL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g16655.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 4 | 575 | 5.4E-155 |
| 2 | g16655.t1 | PANTHER | PTHR11559:SF395 | CARBOXYLIC ESTER HYDROLASE | 8 | 578 | 3.3E-175 |
| 3 | g16655.t1 | PANTHER | PTHR11559 | CARBOXYLESTERASE | 8 | 578 | 3.3E-175 |
| 1 | g16655.t1 | Pfam | PF00135 | Carboxylesterase family | 26 | 567 | 1.1E-134 |
| 10 | g16655.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 20 | - |
| 11 | g16655.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 12 | g16655.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 15 | - |
| 13 | g16655.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 16 | 20 | - |
| 9 | g16655.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 21 | 589 | - |
| 5 | g16655.t1 | ProSitePatterns | PS00941 | Carboxylesterases type-B signature 2. | 107 | 117 | - |
| 6 | g16655.t1 | ProSitePatterns | PS00122 | Carboxylesterases type-B serine active site. | 204 | 219 | - |
| 4 | g16655.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 24 | 570 | 5.72E-123 |
| 7 | g16655.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 20 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K01044 (carboxylesterase 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
