General information for g17068.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Pyrimidodiazepine synthase.
Parent gene
- The parent gene g17068 is located on chr_4: 12384587..12385350 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17068 | g17068.t1 | isoform | g17068.t1 | 12383668 | 12385350 |
| chr_4 | g17068 | g17068.t1 | exon | g17068.t1.exon1 | 12383668 | 12383747 |
| chr_4 | g17068 | g17068.t1 | cds | g17068.t1.CDS1 | 12383668 | 12383747 |
| chr_4 | g17068 | g17068.t1 | exon | g17068.t1.exon2 | 12384202 | 12384311 |
| chr_4 | g17068 | g17068.t1 | cds | g17068.t1.CDS2 | 12384202 | 12384311 |
| chr_4 | g17068 | g17068.t1 | exon | g17068.t1.exon3 | 12384587 | 12385111 |
| chr_4 | g17068 | g17068.t1 | cds | g17068.t1.CDS3 | 12384587 | 12385111 |
| chr_4 | g17068 | g17068.t1 | exon | g17068.t1.exon4 | 12385169 | 12385350 |
| chr_4 | g17068 | g17068.t1 | cds | g17068.t1.CDS4 | 12385169 | 12385350 |
| chr_4 | g17068 | g17068.t1 | TTS | g17068.t1 | 12385416 | 12385416 |
| chr_4 | g17068 | g17068.t1 | TSS | g17068.t1 | NA | NA |
Sequences
>g17068.t1 Gene=g17068 Length=897
ATGAGTGAGAATATAAACAAACTGGATATATTACGTGCTTTCGGTAAAATGTTTGCTTTT
CAAGCTAATGCATCAAAAATCTTATCTTTAATTTCAAAGCATATAAAAAGAACCACAAAT
CATTCAGTCGTTAATCGAATGTCAGCAAGTGAACCAAAAATGACTACAAAAAGTCTTCAT
TTAACTAAAGGTTCATCCCAACCAACATTTCCTGACAATGAAAACCTTCGACTTTATTCA
ATGAAATATTGTCCTTACGCTCATCGAGCTCATTTGGTGCTTGATGCTAAAAACATTCCT
TATCACACAGTTTTTATTAATTTAACTGAAAAACCCGAATGGTATCAAAAAGTCTCTGCA
CTTACAAAAGTTCCAGCTCTGGAATTACCAGAAGTTAAAGGAGATTCTTTGATTGAATCT
TTGATTATTTGTGACTACATTGATGAAAAATATCCACAAAATCAATTGAATTCCAAAGAT
TCATTAGAGAAAGCTCGTGACAGAATTTTAGTGCAAAGATTTGAAACATTGACTCCTGTC
TTTGGTCGTTTTATTTATTGGAAAAATGAGGAAGAAAAGAATAAAATTATAGAAAAGCTC
TATGCAGGATTGACAATTTTTGAGACAGAATTGAAGGAAAGAAATTCAAAATTCTTTGGT
GGTGAAAAACCTAAAATGCTCGATTATATGATTTGGCCTTGGTTTGAAAGATTTGAATTG
CTAAATTTTCTACTTGAACAAAAGTTTGAATTAAATCATTTTTCAAAATTATCCACATGG
TTTGATGGAATGATGAAAGATGAAGCTGTGAAGAAAAATTTCATAAACATTGACGATCAT
TATAGATTTGTCAAAACGAGAAATTACGATAATGTTGCTGGATGTATAGAAAAGTAA
>g17068.t1 Gene=g17068 Length=298
MSENINKLDILRAFGKMFAFQANASKILSLISKHIKRTTNHSVVNRMSASEPKMTTKSLH
LTKGSSQPTFPDNENLRLYSMKYCPYAHRAHLVLDAKNIPYHTVFINLTEKPEWYQKVSA
LTKVPALELPEVKGDSLIESLIICDYIDEKYPQNQLNSKDSLEKARDRILVQRFETLTPV
FGRFIYWKNEEEKNKIIEKLYAGLTIFETELKERNSKFFGGEKPKMLDYMIWPWFERFEL
LNFLLEQKFELNHFSKLSTWFDGMMKDEAVKKNFINIDDHYRFVKTRNYDNVAGCIEK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g17068.t1 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 60 | 286 | 5.5E-77 |
| 9 | g17068.t1 | Gene3D | G3DSA:1.20.1050.10 | - | 157 | 275 | 5.5E-77 |
| 11 | g17068.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 42 | 66 | - |
| 3 | g17068.t1 | PANTHER | PTHR43968 | - | 56 | 285 | 1.4E-64 |
| 5 | g17068.t1 | PRINTS | PR01625 | Omega-class glutathione S-transferase signature | 74 | 89 | 1.7E-17 |
| 6 | g17068.t1 | PRINTS | PR01625 | Omega-class glutathione S-transferase signature | 151 | 165 | 1.7E-17 |
| 4 | g17068.t1 | PRINTS | PR01625 | Omega-class glutathione S-transferase signature | 218 | 237 | 1.7E-17 |
| 2 | g17068.t1 | Pfam | PF13417 | Glutathione S-transferase, N-terminal domain | 78 | 154 | 1.3E-20 |
| 1 | g17068.t1 | Pfam | PF13410 | Glutathione S-transferase, C-terminal domain | 193 | 262 | 2.4E-6 |
| 13 | g17068.t1 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 74 | 155 | 18.494 |
| 12 | g17068.t1 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 160 | 292 | 16.445 |
| 14 | g17068.t1 | SFLD | SFLDG00358 | Main (cytGST) | 76 | 266 | 8.0E-41 |
| 15 | g17068.t1 | SFLD | SFLDS00019 | Glutathione Transferase (cytosolic) | 76 | 266 | 8.0E-41 |
| 7 | g17068.t1 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 75 | 175 | 2.36E-23 |
| 8 | g17068.t1 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 159 | 287 | 5.43E-26 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004364 | glutathione transferase activity | MF |
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
| GO:0005737 | cytoplasm | CC |
KEGG
Orthology
- This transcript has been annotated with K00799 (glutathione S-transferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed