General information for g17513.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Lipase 1.
Parent gene
- The parent gene g17513 is located on chr_4: 13763930..13765025 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g17513 | g17513.t1 | isoform | g17513.t1 | 13762051 | 13763930 |
| chr_4 | g17513 | g17513.t1 | exon | g17513.t1.exon1 | 13762051 | 13762200 |
| chr_4 | g17513 | g17513.t1 | cds | g17513.t1.CDS1 | 13762051 | 13762200 |
| chr_4 | g17513 | g17513.t1 | exon | g17513.t1.exon2 | 13762254 | 13763005 |
| chr_4 | g17513 | g17513.t1 | cds | g17513.t1.CDS2 | 13762254 | 13763005 |
| chr_4 | g17513 | g17513.t1 | exon | g17513.t1.exon3 | 13763065 | 13763260 |
| chr_4 | g17513 | g17513.t1 | cds | g17513.t1.CDS3 | 13763065 | 13763260 |
| chr_4 | g17513 | g17513.t1 | exon | g17513.t1.exon4 | 13763892 | 13763930 |
| chr_4 | g17513 | g17513.t1 | cds | g17513.t1.CDS4 | 13763892 | 13763930 |
| chr_4 | g17513 | g17513.t1 | TSS | g17513.t1 | NA | NA |
| chr_4 | g17513 | g17513.t1 | TTS | g17513.t1 | NA | NA |
Sequences
>g17513.t1 Gene=g17513 Length=1137
ATGTGGATAAAATCAAGAAATGAGAATTTTATTGAAAAGGAAAATCTCATTATATCAAAC
GGTTATATTGGTGTAGCTCATATAATGGAAACAAGAGACAACTATATACTTACTGTTCAT
CGAATTCGTTCAAAATCTCAACCTGCATATAAAAAACTTCAGCCTGTTTTATTTATGCAT
GGACTGGCAATGACTGGTGGTGATTTTATTGAGCTTGGACCTAATAATGCCCTACCTTAT
CTTTTAGCTGATTTAGGTTATGAATGTTGGTTAGGAAACAGCAGAGGTACTGACTATAGT
CTTGGTCATCGTTTCATTAGCAATGATACAAAAGAATTTTGGGATTTCTCTTTCCATGAA
ATTGGACTTTTTGATCTTCCTGCAATGATTGATTTTGTACTTTCTTATTCAAGAGCTAGA
AAACTTTTTTACATTTGTCATTCACAAGGTTGCTCAGCTCTTATGGTTTTAATTTCACTT
CAACCACATTACAATGAGAAGATTTTTGAAGCTCATCTTTATAGTCCTGCAGTTTTCATG
AAAAATTCTGAACGTCAAATTTATATATTTTTTGAGACTCCGATAAATGCTTTTGCATCA
CTTACTAAAAGATATGACATTTTATCAAAAATTCCCTACCTTTTTATGCTTACTTTTTTA
ACTGATGTTTTTTGCCACACTGACTTAATCACAATAGAATTTTGCAAGTTTGTCTATAAA
TTAGTATGTGGATTTAATGAAAATGGAACTGAAACTGATATGAACAATATGGCATTAATG
ATGAGACTTTTGCCGCGAGCTGTAAGTTTAAAACAAATCGTACATTTCAGTCAGTTGCTA
CATACCGAAAGATTTTTACATTATAATTATGGAGAAAAAAATATTGAAATTTATGGACAA
AATGAACCACCTGAATATGACTTGAGAAATGTTCAAATTCGAATTTACATTTATGCTGGT
AAAAATGATTTGCTTATAAATTTAAAGGATCTTGAGCATTTTCGTGATATTTTACCAAAT
GTTAAAAGATTCAAAGTTCTTGAAAATTATAATCATTGTGATTTCAATTATGGAATAAAT
TCAAAGAAATTGGTTTATGATTTTATCATCAAATCTATTCTTAAATATAAAAAATAA
>g17513.t1 Gene=g17513 Length=378
MWIKSRNENFIEKENLIISNGYIGVAHIMETRDNYILTVHRIRSKSQPAYKKLQPVLFMH
GLAMTGGDFIELGPNNALPYLLADLGYECWLGNSRGTDYSLGHRFISNDTKEFWDFSFHE
IGLFDLPAMIDFVLSYSRARKLFYICHSQGCSALMVLISLQPHYNEKIFEAHLYSPAVFM
KNSERQIYIFFETPINAFASLTKRYDILSKIPYLFMLTFLTDVFCHTDLITIEFCKFVYK
LVCGFNENGTETDMNNMALMMRLLPRAVSLKQIVHFSQLLHTERFLHYNYGEKNIEIYGQ
NEPPEYDLRNVQIRIYIYAGKNDLLINLKDLEHFRDILPNVKRFKVLENYNHCDFNYGIN
SKKLVYDFIIKSILKYKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g17513.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 3 | 374 | 0 |
| 2 | g17513.t1 | PANTHER | PTHR11005:SF127 | LIPASE-RELATED | 10 | 377 | 0 |
| 3 | g17513.t1 | PANTHER | PTHR11005 | LYSOSOMAL ACID LIPASE-RELATED | 10 | 377 | 0 |
| 6 | g17513.t1 | PIRSF | PIRSF000862 | Steryl_ester_lip | 3 | 378 | 0 |
| 1 | g17513.t1 | Pfam | PF04083 | Partial alpha/beta-hydrolase lipase region | 16 | 70 | 0 |
| 4 | g17513.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 27 | 371 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016788 | hydrolase activity, acting on ester bonds | MF |
| GO:0006629 | lipid metabolic process | BP |
KEGG
Orthology
- This transcript has been annotated with K01052 (lysosomal acid lipase/cholesteryl ester hydrolase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
