Gene loci information

Transcript annotation

  • This transcript has been annotated as Kynureninase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
HiC_scaffold_373 g17803 g17803.t1 isoform g17803.t1 34330 35380
HiC_scaffold_373 g17803 g17803.t1 exon g17803.t1.exon1 34330 34646
HiC_scaffold_373 g17803 g17803.t1 cds g17803.t1.CDS1 34330 34646
HiC_scaffold_373 g17803 g17803.t1 exon g17803.t1.exon2 34727 35272
HiC_scaffold_373 g17803 g17803.t1 cds g17803.t1.CDS2 34727 35272
HiC_scaffold_373 g17803 g17803.t1 exon g17803.t1.exon3 35332 35380
HiC_scaffold_373 g17803 g17803.t1 cds g17803.t1.CDS3 35332 35380
HiC_scaffold_373 g17803 g17803.t1 TSS g17803.t1 NA NA
HiC_scaffold_373 g17803 g17803.t1 TTS g17803.t1 NA NA

Sequences

>g17803.t1 Gene=g17803 Length=912
ATGGATTTATTTGAGATTGATTCACTTAAAAATAATTCAAAAAATGAAGTTGAAAAAGAA
AATATTTTACAATCAAATCTGATGACATTTGAAGAATGTGTAAAAGCTGATGAAAATGAC
GAATTAAAAAATTTTTGTAGTAAATTTCAAATTCCTCCAAATACAATTTATTTTTGTGGA
AATTCTCTTGGTCTCTGTCCAATTGAATCAGAAAAAGTTGTAAATCAAATTATACAAGAA
TGGGAACAAAATCACATTCATTCATGGAACCTTGCGATTCAATTGCCATTAAAAGTTGGT
AATAAAATTGGAAAATTGATCGGTGCAGAAGAAAATGAAACAATTATTGCCGATTCAACT
TCAATAAATCTTTTTAAATGCCTCGGAACTTCAATTGCAATTCAAAAAATTAAAAATCCT
AATCGTCGTTCAATTTTGTTAGATCGTGAAAATTTTTCAAATGACTTGGGTCTCCTTAAA
CTTCTTTCAACTGATGAATATAAAATTCGCTATTTTGATGACGAAAATCAACTCGAAGAT
TTTTTAAATGATGATGTTGTATGCATTTTGCTATCACATGTAAATTATCATCATGTTGGT
TCTGTTCCAATCAACTTGACTGAAGTTAATGCTGATTTTGCAGTTGGTTGTACTGATAAA
TATTTAAATAGCAGTCCAGGGGCTCCTGCATTTATTTATGTTAATAAAAAACATCAAAAT
GTCACTTGGCAACCACTGACTGGTTGGCTTGGTCATCAATCACCTTTTAAAATGTCAAAA
GATTATGAACCTACTGTAGGAATCAAAAATTTTCTTGTTGGAACGCCAGAAGTTTTGCCA
ATTTCAATTATTGATTGTAGTGTTGAAATTACACTTGATGCTGGCATGCAACTGATTAGA
AAAAATCATTAG

>g17803.t1 Gene=g17803 Length=303
MDLFEIDSLKNNSKNEVEKENILQSNLMTFEECVKADENDELKNFCSKFQIPPNTIYFCG
NSLGLCPIESEKVVNQIIQEWEQNHIHSWNLAIQLPLKVGNKIGKLIGAEENETIIADST
SINLFKCLGTSIAIQKIKNPNRRSILLDRENFSNDLGLLKLLSTDEYKIRYFDDENQLED
FLNDDVVCILLSHVNYHHVGSVPINLTEVNADFAVGCTDKYLNSSPGAPAFIYVNKKHQN
VTWQPLTGWLGHQSPFKMSKDYEPTVGIKNFLVGTPEVLPISIIDCSVEITLDAGMQLIR
KNH

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g17803.t1 Gene3D G3DSA:3.40.640.10 - 68 197 0
7 g17803.t1 Gene3D G3DSA:3.40.640.10 - 198 291 0
2 g17803.t1 PANTHER PTHR14084 KYNURENINASE 24 156 0
4 g17803.t1 PANTHER PTHR14084:SF0 KYNURENINASE 24 156 0
1 g17803.t1 PANTHER PTHR14084 KYNURENINASE 197 301 0
3 g17803.t1 PANTHER PTHR14084:SF0 KYNURENINASE 197 301 0
5 g17803.t1 SUPERFAMILY SSF53383 PLP-dependent transferases 29 303 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0030429 kynureninase activity MF
GO:0006569 tryptophan catabolic process BP
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF
GO:0005737 cytoplasm CC
GO:0009435 NAD biosynthetic process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed