General information for g17819.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Tyrosine-protein kinase HTK16.
Parent gene
- The parent gene g17819 is located on HiC_scaffold_382: 1..1000 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| HiC_scaffold_382 | g17819 | g17819.t1 | isoform | g17819.t1 | 1 | 1000 |
| HiC_scaffold_382 | g17819 | g17819.t1 | exon | g17819.t1.exon1 | 1 | 362 |
| HiC_scaffold_382 | g17819 | g17819.t1 | cds | g17819.t1.CDS1 | 1 | 362 |
| HiC_scaffold_382 | g17819 | g17819.t1 | exon | g17819.t1.exon2 | 411 | 1000 |
| HiC_scaffold_382 | g17819 | g17819.t1 | cds | g17819.t1.CDS2 | 411 | 885 |
| HiC_scaffold_382 | g17819 | g17819.t1 | TSS | g17819.t1 | NA | NA |
| HiC_scaffold_382 | g17819 | g17819.t1 | TTS | g17819.t1 | NA | NA |
Sequences
>g17819.t1 Gene=g17819 Length=952
AAATTATGACGTTCCTCCGACATCAAAGAGGCCATCAACACAAGAAGATCAATTTACAGA
AAGCGATCAATTTTTAATAAACAATCAAACAGTTCAAGACTCAAAACCACAAGAAATGAT
TTATTTCATGGATCCACCAAAAAGGAATAAAATAGAATGGAATCAACTTGATCCGGAATT
GTATGAAACGCAAAAGAACTTTTTAAAAGAAATTACTCGAAGTTCTGGTGCAAATTATTA
TGTCTCAAAAGATGATCTACATTTTGACAATGAAATTGGTTCAGGAGAATTTGGAAATGT
CTTAAGGGGAATTTTTAAATTATCAAATGGCAAGAAAATTTGGGTTGCAATAAAAACTTT
ACATGAGAGGCATTATGAAGAAAATCTTCCAGAATTTTTAAAAGAAGCTTCAGTTATGAT
AAAATTAGACAATCCATATGTCGTAAAACTAATAGGAATTTGTAAAGGACCGCCAATTGG
AATTGTTCAAGAGCTCTGTAGTTTCGGATCACTCGCTGACTATTTAGTAGAAAACAAAGA
TGATATCGATAATAAATTAATTGACTTGTGGGCGTCTCAAATTGCACAAGCTCGCAATAT
TTTACTCGTCTCGAAGCAACATTGCAAAATATCTGACTTTGGTCTCTCACGTGCCATTGG
AATCGATAAAGATTTCTATCAATCAAGTACTGGTGGACGCTGGCCATTAAAATGGTATGC
GCCTGAATCTTTCTGTGGAAAATTTTCTCATTCAAGTGATGTGTGGAGTTTCGGTATAAC
TTTGTGGGAAATTTATTCAAAAGGTGATGTACCCTATGATGATTTGTCTGGAAGTGAAGT
CAATGAATTAATTGAGAAAGGTCAGCGTCTTGCAAGACCAGAATGTTGTCCAGAAGATGT
GTATAGTCTTATGCTTGATTGTTGGAATTACAGAGCACGACTTCGACCACGA
>g17819.t1 Gene=g17819 Length=279
MIYFMDPPKRNKIEWNQLDPELYETQKNFLKEITRSSGANYYVSKDDLHFDNEIGSGEFG
NVLRGIFKLSNGKKIWVAIKTLHERHYEENLPEFLKEASVMIKLDNPYVVKLIGICKGPP
IGIVQELCSFGSLADYLVENKDDIDNKLIDLWASQIAQARNILLVSKQHCKISDFGLSRA
IGIDKDFYQSSTGGRWPLKWYAPESFCGKFSHSSDVWSFGITLWEIYSKGDVPYDDLSGS
EVNELIEKGQRLARPECCPEDVYSLMLDCWNYRARLRPR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g17819.t1 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 35 | 127 | 2.0E-23 |
| 7 | g17819.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 158 | 279 | 1.8E-36 |
| 2 | g17819.t1 | PANTHER | PTHR24418 | TYROSINE-PROTEIN KINASE | 35 | 279 | 2.4E-101 |
| 3 | g17819.t1 | PANTHER | PTHR24418:SF372 | TYROSINE-PROTEIN KINASE SHARK | 35 | 279 | 2.4E-101 |
| 9 | g17819.t1 | PIRSF | PIRSF000615 | TyrPK_CSF1-R | 40 | 158 | 1.0E-9 |
| 10 | g17819.t1 | PIRSF | PIRSF000615 | TyrPK_CSF1-R | 154 | 279 | 8.1E-36 |
| 1 | g17819.t1 | Pfam | PF07714 | Protein tyrosine and serine/threonine kinase | 48 | 278 | 1.3E-63 |
| 5 | g17819.t1 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 54 | 80 | - |
| 8 | g17819.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 48 | 279 | 22.478 |
| 4 | g17819.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 39 | 278 | 1.25E-57 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K05855 (spleen tyrosine kinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
