Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Wiskott-Aldrich syndrome protein.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g1795 g1795.t3 isoform g1795.t3 13055641 13057099
chr_3 g1795 g1795.t3 exon g1795.t3.exon1 13055641 13056799
chr_3 g1795 g1795.t3 cds g1795.t3.CDS1 13056461 13056799
chr_3 g1795 g1795.t3 exon g1795.t3.exon2 13057000 13057099
chr_3 g1795 g1795.t3 cds g1795.t3.CDS2 13057000 13057098
chr_3 g1795 g1795.t3 TSS g1795.t3 NA NA
chr_3 g1795 g1795.t3 TTS g1795.t3 NA NA

Sequences

>g1795.t3 Gene=g1795 Length=1259
TAACGATATTTTGAATTTCAATTTTGAACCAATCTCTAATGTTCAAAGATTGAGGATCAA
AAATTTTCATTCACTTTTGTGTGTGCATTTTGTCGAAAAAAATTAAAATTTCTTAATTAA
GCAAACAAAATGCTATAATTGTGTCAAATTTTACTAATATATTGTGTAACTAATTATGAA
CAGAACAATGCAACTAAATGTTTAATTATAAGAGTCAAGAAAAAGATATAAAAATGAAGT
GAGATAGTGAATGATTAATTTTTTTGGAGTTTGAAAAAGAGTCAAAGAAGAAACAAGGCT
GAAATGAACAAAATGAGTCCACAACTGATAAGAAAGCTAAAGAGTTGGCGTTTATCACAA
AGCTAAAACAGGCAAATAGTTCATAAACTGTCCTGCAGTGATACACAACTCGACCAATAA
AATAATAGAATTGAAACAAACGAGACATTATATTGTTAAAGAATAAAATAAGGCCACGGC
AAAATAAAAGTAAAAAATATAAAAATTGTTATGAATGATGATGATGATGATGAACAGAGA
GAGAAAAACGCATGAGTGTTAAACAAGCTAAATGGAGAAAAGGCAGCAAATTGCAAAATC
ATTAAATTCAATTGTTGTTTGAAAGAGTTTTATCACTTGTTTCAAAATTGTTAAGTTATT
AAGCGTATTTTATATGGTGTGTAGTGTTTATTTGTGTCTATTGTGTTACCAATTAATTAT
TCGCGAGCGAGAAATTCAATGCATGCACAAAATTTTTAATTCGTTTGTATTTACGACAAT
TATTAGGAAGTTTATCAAAAGCAATTAAATGCAATAAAAAATGTCTGCAAATAGTGAAAA
TAGAAATTCAACAAAATTATCAAAGTCATCAACATATCTCTCTGGAGAAGAGAATGATCT
AGTATTTCGTCTTCTTGGAAGAAGATGTCAAAGCCAATGTACAACAGTAGCACAACTTTA
TCAAACAGAAGCTCCAACACATTGTCGCTGGGTGAAAAAGTACACGGGAGCATTATGTTT
TGTAAAGGACAATGCTAAGCGATCATATTATGCGCGACTATTTTGTCTCATAAAGCATGA
AATGATGTGGGAACAAGAAATGTATGACACTATTGAAATCAGCCGTGTTAAGCCTTACTT
ACTCACATTTGAAGGACAGGACGGTATGGTGGCATTGAATTTTGCATTTGAGGATGAGGC
CGAGACTTTTTTACATGTTGCAACAACAACTGTTCAAAATAGAAATAGACGGAGAGAAG

>g1795.t3 Gene=g1795 Length=146
MSANSENRNSTKLSKSSTYLSGEENDLVFRLLGRRCQSQCTTVAQLYQTEAPTHCRWVKK
YTGALCFVKDNAKRSYYARLFCLIKHEMMWEQEMYDTIEISRVKPYLLTFEGQDGMVALN
FAFEDEAETFLHVATTTVQNRNRRRE

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g1795.t3 CDD cd01205 EVH1_WASP-like 40 141 0.000000
6 g1795.t3 Gene3D G3DSA:2.30.29.30 - 4 146 0.000000
2 g1795.t3 PANTHER PTHR23202:SF79 WASP ACTIN NUCLEATION-PROMOTING FACTOR A-RELATED 9 145 0.000000
3 g1795.t3 PANTHER PTHR23202 WASP INTERACTING PROTEIN-RELATED 9 145 0.000000
1 g1795.t3 Pfam PF00568 WH1 domain 29 133 0.000000
7 g1795.t3 ProSiteProfiles PS50229 WH1 domain profile. 32 141 18.122000
5 g1795.t3 SMART SM00461 WH1_2 32 138 0.000032
4 g1795.t3 SUPERFAMILY SSF50729 PH domain-like 28 140 0.000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003779 actin binding MF
GO:0007015 actin filament organization BP
GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values