Gene loci information

Transcript annotation

  • This transcript has been annotated as Hexokinase type 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g1897 g1897.t1 TTS g1897.t1 13736384 13736384
chr_3 g1897 g1897.t1 isoform g1897.t1 13736582 13738302
chr_3 g1897 g1897.t1 exon g1897.t1.exon1 13736582 13736729
chr_3 g1897 g1897.t1 cds g1897.t1.CDS1 13736582 13736729
chr_3 g1897 g1897.t1 exon g1897.t1.exon2 13736957 13737618
chr_3 g1897 g1897.t1 cds g1897.t1.CDS2 13736957 13737618
chr_3 g1897 g1897.t1 exon g1897.t1.exon3 13737693 13737787
chr_3 g1897 g1897.t1 cds g1897.t1.CDS3 13737693 13737787
chr_3 g1897 g1897.t1 exon g1897.t1.exon4 13737849 13738302
chr_3 g1897 g1897.t1 cds g1897.t1.CDS4 13737849 13738302
chr_3 g1897 g1897.t1 TSS g1897.t1 13738426 13738426

Sequences

>g1897.t1 Gene=g1897 Length=1359
ATGACAAACTCTATTCCACAAAAAGTGCATGACGCGATCGATAGAGATTTAGTACTAGAT
AACAAGAAATTAAATGATGTAATGGTAAAGTTTGAAAGAGAAATTAAAAAGGGTCTTTCA
AAGGCGCATCATGATGAATCGGAAGTAAAATGTTTTGTGACATATGTTCAAAATTTACCA
ATGGGAACTGAAAAGGGCAAATTTTTAGCTCTTGATTTGGGTGGCACGAATTTTCGTGTG
CTTCTTATTATTCTCAAGGGAGAAGAAGATTATGAATTTAAATCAAAAATTTTTGCTATC
CCTCAATCTTTAATGGTCGGCTCTGGTCGTGATTTATTTGATCATATTGCGCAATGTTTG
GCAGAATTCATAAAAGATATGAACATTCAAAATGAGATTTTGCCTCTCGGATTCACTTTT
AGTTTTCCCTGTCAACAAAAAGGACTAACCACTGGCACCCTCATTAAATGGACCAAAGGG
TTTAATTGTAGTGACGTTGTTGAGAAAAATGTAGTTGAGTTATTAGAAGAGGCAATTCAA
CGTCGTAATGATATTAAAATTTTAATTTGTGCTATACTTAATGATACAACCGGAACTCTC
ATGTCTTGTGCATGGAAATATCAAGACTGTAAAATTGGAGTTATAATTGGAACCGGCTCT
AATGCCTGTTATGTAGAGAAGGTCAGATACGCAGAGTGGTTTGATAAACCCGGAAAATTT
GACGATGAAAGCGTGATCATCAATACAGAGTTTGGTGCATTCGGAGACAAAGGCAGTTTG
GATGATATTCGAACATGTTTTGATATTGAAGTTGATAAAAATAGCATAAACCCGAGTAAT
CAATTGTTTGAGAAAATGATTTCGGGAATGTATATGGGTGAACTTGTTAGATTGGTCATT
GTGAAATTAGCCTCAAAAGGTTTAATTTTCAATGGCAAAATTTCTAAGAAATTTATGCAA
CGAGAAACATTTTTTACAAAATATATTTCTGAAATTGAGCATGAAGAAAATAATGTTTTT
CATGCAACAAAAGAAATTTTGTATGAACTGGATATTGAAAATCCAACCGAAGAAGATTGT
CGTATTGTTCGATATTGTTGCGAATTGATAAGCAAGCGAGCAGCACAACTCGTTTCAAGT
GGTTTAGCAGTTCTTATGCTACGTATTGGTGATCCGAAGATCACTATCGGCGTTGATGGC
TCTGTATATAGGTTTCACCCCCGCTTTCATGATCTTATGACCGAAACTATAAAACAATTG
ATTCCATCAAATTATGAATTTAAATTGGTACTTTCCGAAGATGGCAGCGGCAGAGGAGCT
GCTTTAGTTGCAGCTGTAGCATCTAAGGATCTTCAATGA

>g1897.t1 Gene=g1897 Length=452
MTNSIPQKVHDAIDRDLVLDNKKLNDVMVKFEREIKKGLSKAHHDESEVKCFVTYVQNLP
MGTEKGKFLALDLGGTNFRVLLIILKGEEDYEFKSKIFAIPQSLMVGSGRDLFDHIAQCL
AEFIKDMNIQNEILPLGFTFSFPCQQKGLTTGTLIKWTKGFNCSDVVEKNVVELLEEAIQ
RRNDIKILICAILNDTTGTLMSCAWKYQDCKIGVIIGTGSNACYVEKVRYAEWFDKPGKF
DDESVIINTEFGAFGDKGSLDDIRTCFDIEVDKNSINPSNQLFEKMISGMYMGELVRLVI
VKLASKGLIFNGKISKKFMQRETFFTKYISEIEHEENNVFHATKEILYELDIENPTEEDC
RIVRYCCELISKRAAQLVSSGLAVLMLRIGDPKITIGVDGSVYRFHPRFHDLMTETIKQL
IPSNYEFKLVLSEDGSGRGAALVAAVASKDLQ

Protein features from InterProScan

Transcript Database ID Name Start End E.value
16 g1897.t1 CDD cd00012 NBD_sugar-kinase_HSP70_actin 69 227 5.97416E-10
15 g1897.t1 Gene3D G3DSA:3.40.367.20 - 17 433 8.1E-166
14 g1897.t1 Gene3D G3DSA:3.30.420.40 - 54 443 8.1E-166
3 g1897.t1 PANTHER PTHR19443:SF4 HEXOKINASE-2 16 449 4.8E-168
4 g1897.t1 PANTHER PTHR19443 HEXOKINASE 16 449 4.8E-168
7 g1897.t1 PRINTS PR00475 Hexokinase family signature 69 85 5.4E-72
11 g1897.t1 PRINTS PR00475 Hexokinase family signature 136 161 5.4E-72
8 g1897.t1 PRINTS PR00475 Hexokinase family signature 189 205 5.4E-72
9 g1897.t1 PRINTS PR00475 Hexokinase family signature 212 226 5.4E-72
5 g1897.t1 PRINTS PR00475 Hexokinase family signature 281 303 5.4E-72
10 g1897.t1 PRINTS PR00475 Hexokinase family signature 363 385 5.4E-72
6 g1897.t1 PRINTS PR00475 Hexokinase family signature 430 446 5.4E-72
2 g1897.t1 Pfam PF00349 Hexokinase 12 205 6.1E-68
1 g1897.t1 Pfam PF03727 Hexokinase 211 446 4.6E-80
17 g1897.t1 ProSitePatterns PS00378 Hexokinase domain signature. 136 161 -
18 g1897.t1 ProSiteProfiles PS51748 Hexokinase domain profile. 4 445 49.674
12 g1897.t1 SUPERFAMILY SSF53067 Actin-like ATPase domain 8 206 1.3E-70
13 g1897.t1 SUPERFAMILY SSF53067 Actin-like ATPase domain 209 449 2.16E-79

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0001678 cellular glucose homeostasis BP
GO:0005524 ATP binding MF
GO:0016773 phosphotransferase activity, alcohol group as acceptor MF
GO:0006096 glycolytic process BP
GO:0005975 carbohydrate metabolic process BP
GO:0005536 glucose binding MF
GO:0004396 hexokinase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values