Gene loci information

Transcript annotation

  • This transcript has been annotated as Anaphase-promoting complex subunit 4.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g1972 g1972.t9 isoform g1972.t9 14154000 14156285
chr_3 g1972 g1972.t9 exon g1972.t9.exon1 14154000 14156285
chr_3 g1972 g1972.t9 cds g1972.t9.CDS1 14154032 14156107
chr_3 g1972 g1972.t9 TTS g1972.t9 14156355 14156355
chr_3 g1972 g1972.t9 TSS g1972.t9 NA NA

Sequences

>g1972.t9 Gene=g1972 Length=2286
GTGAAGTAACAATTAATAGATTTAAATGGGATATGCCGATTAAAATATTACCACCAGAAG
AAAAGATTGCTGTCAAGTCAATTTCATGGAGGATGGATGAAAGAATTATAGGAATAGCAT
ATAACAATCAACTTATAAATTTGGTTGATATTGAATCAAAAGAAGTAATCATTTCATACA
GTGTAAATGCAGATGTCACTAAAATTTGTTGGACTCAGAATTCAATAGATATAGATTCAA
ATGAAAAATCAATTCTAGATGATCATGTTTTTCTAGCTTCTTTGCCAAGTATCAATAGTA
CAATATCTTCCGGAACTAAAAAGAGTGACTACAATAGCACACGCTTCTACTCGAATACTG
GATTAAATTTTCTCATTGTAATCTGTAATGATTGTACAATAAGAGCCTACATATATGGTG
TTCTCTCATGTGGATCGATTGATGTTAAAAAGAAACTTAATGTAAATGAATCTGATTCAC
TGAATATAATAGAAGCAAAAATGAGTTCAAATTTCGAACGATTCTTTGTTGTTTATGTAA
AAAATGGCATTCTGGGAACTCTTGTTTTTGAGAATTCAGCTCTTCTTAAGCGACATGTTG
CATTGTGGAAACTATCGATCAAGTATGGAATGATATTAAATATTTTTGAATACATGGATG
ACACTATTGAACATATTAATGAAGCTTGGGAGTCAGTTTTACTTGAGATGGACAATAAAC
TATCAAAATATGCTAAAAAGCAAGAGGCAGGCTCAATTTCTGCAGACTTTTTGGAGTTAC
TACTCTTTGGATATCCATCTGAAGAATTAGAAAATTTTCTTACTCATGAAATGACTGTAA
GAGAATTGAAGAAACTCAGTAATAGTGTTGAAATGAGTTATAGTACAATACAAAAGCTCG
TTGTAAAACCACTACATAGTGCTATAATTTCAATATTCTATCATGTCAATAATCTTCATG
GAATGCATCAAAATGCATATGAATATAAAAATCTTTTGGGTGAGAATTCAAGTGAAGCGC
TTATTTCGACTGGATCGTTTCTCATAAAATCTCACGAATTACAACAAATTATTGATAAAT
CAATGAGAGATTTTAAAATTTTCTTTCGCTGGCTGTATATTGCAATTTCGAGATTAATGG
ATGACACAGTTCCTGATGATGCAGGAGTTATTACTCAGCAAGAAGTTAATTATTTGGCTG
AATTTTTATACAATTTCGAAGAGAATAGAAAAGAGTTGGTTCATGATGAGTCAGGTGAAA
AAGAGATAAAATTTAATTTGGAACGTGTTGGTCAATATTTAACAAATCAAAATCTTACAA
TTCCTTCTATCGATAACACTTCTAATATTTGGAATGAAATTTTCACACAAAATGAATGTT
TGCAAACCAGCAAATTGATTTATCCACACAATAAAGATTCATCTCTTATTCAAGAAAAAA
ATAAAATGGAGAAAAGTATCAAAGATTTATTCAATAGATTAGAGCATTCGATTGGTCAAG
AGTATAATTTGAAAAATGATTTTATAATTTCTCATTCTGATGACATTGCATCATCTACAA
TTGTCACTTCACACATAATCGATGGAGAGAATCAAGATGCAATTAATCTATTTACAATTT
TACTATCTGAGAAAGATTTATTGCTGCTCGTTTATTATTCCAATACATATATTCCAAAAA
TTGCCAAGTTACAATTTACAAATCGAGATGAATGCAATATTTTGTCTGTGGGACAGCTTT
CATTCATTGATATAAAATTTTACAACACGAGATTGCTATCAGGATTAATTAAGAATGAAA
TTGGAAACAAAATTCAAACATGCTTCATTCAAGTACCTGTATCACGTCTCATTGATGAGC
TACTCGAATATGATCAAAAAACCATTCCCACATTTAATATGTATAATTATATAGACGACT
GTAATTTTAAAGTCATTGAAGGTTTTGCAGGCAATTTAATGGCAGTGTCTGGGTCTCGAA
AAGTTGCAGCATTTTTGGCATCAAATCAAAAAATTGTAAAACTTTATGAACTCGAGGTAG
ATGAAGATGATGAGTGTGATGAAGAAAATTCAAATAATGCAAGTTTTGAAATAGAAATGA
AAATGTAAATCATTTATAATTTTGTTAGATGAAATTTCCTTTATTAACTTAATTCAGATG
TTGATTGAGATTTCTGCATTTAAGATTTATAATAAAGTGTGAGAATTAAATTATAATTGT
AGAAAAGGAAATGATAAAGACTTTGATGTAATTTTTTATTAAATATGCATGCTTGGTTGT
CCATTT

>g1972.t9 Gene=g1972 Length=691
MPIKILPPEEKIAVKSISWRMDERIIGIAYNNQLINLVDIESKEVIISYSVNADVTKICW
TQNSIDIDSNEKSILDDHVFLASLPSINSTISSGTKKSDYNSTRFYSNTGLNFLIVICND
CTIRAYIYGVLSCGSIDVKKKLNVNESDSLNIIEAKMSSNFERFFVVYVKNGILGTLVFE
NSALLKRHVALWKLSIKYGMILNIFEYMDDTIEHINEAWESVLLEMDNKLSKYAKKQEAG
SISADFLELLLFGYPSEELENFLTHEMTVRELKKLSNSVEMSYSTIQKLVVKPLHSAIIS
IFYHVNNLHGMHQNAYEYKNLLGENSSEALISTGSFLIKSHELQQIIDKSMRDFKIFFRW
LYIAISRLMDDTVPDDAGVITQQEVNYLAEFLYNFEENRKELVHDESGEKEIKFNLERVG
QYLTNQNLTIPSIDNTSNIWNEIFTQNECLQTSKLIYPHNKDSSLIQEKNKMEKSIKDLF
NRLEHSIGQEYNLKNDFIISHSDDIASSTIVTSHIIDGENQDAINLFTILLSEKDLLLLV
YYSNTYIPKIAKLQFTNRDECNILSVGQLSFIDIKFYNTRLLSGLIKNEIGNKIQTCFIQ
VPVSRLIDELLEYDQKTIPTFNMYNYIDDCNFKVIEGFAGNLMAVSGSRKVAAFLASNQK
IVKLYELEVDEDDECDEENSNNASFEIEMKM

Protein features from InterProScan

Transcript Database ID Name Start End E.value
3 g1972.t9 PANTHER PTHR13260 ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4 5 677 0e+00
2 g1972.t9 Pfam PF12894 Anaphase-promoting complex subunit 4 WD40 domain 8 63 2e-07
1 g1972.t9 Pfam PF12896 Anaphase-promoting complex, cyclosome, subunit 4 181 371 0e+00

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0031145 anaphase-promoting complex-dependent catabolic process BP
GO:0030071 regulation of mitotic metaphase/anaphase transition BP
GO:0005680 anaphase-promoting complex CC

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values