General information for g1988.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Aldo-keto reductase family 1 member A1-A.
Parent gene
- The parent gene g1988 is located on chr_3: 14233347..14234444 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1988 | g1988.t1 | TSS | g1988.t1 | 14233311 | 14233311 |
| chr_3 | g1988 | g1988.t1 | isoform | g1988.t1 | 14233347 | 14234444 |
| chr_3 | g1988 | g1988.t1 | exon | g1988.t1.exon1 | 14233347 | 14233403 |
| chr_3 | g1988 | g1988.t1 | cds | g1988.t1.CDS1 | 14233347 | 14233403 |
| chr_3 | g1988 | g1988.t1 | exon | g1988.t1.exon2 | 14233591 | 14233686 |
| chr_3 | g1988 | g1988.t1 | cds | g1988.t1.CDS2 | 14233591 | 14233686 |
| chr_3 | g1988 | g1988.t1 | exon | g1988.t1.exon3 | 14233758 | 14234444 |
| chr_3 | g1988 | g1988.t1 | cds | g1988.t1.CDS3 | 14233758 | 14234444 |
| chr_3 | g1988 | g1988.t1 | TTS | g1988.t1 | 14234492 | 14234492 |
Sequences
>g1988.t1 Gene=g1988 Length=840
ATGTTTCGTTTACTGAATAATTTGACAATTCCATTTATTGGAATGGGAACAGGCAAATTG
AAGGGCGAATTAGGAGTGACAGCAATTAAAGAAGCAATAGATGCCGGCTATCGACTTTTT
GACACGGCTTTTTTGTATGATAACGAGAATATCCTTTGGGGCATTCATCACGATCAAGTA
GAACGAGCTTGTCGTGATTCATGCAAACGATTGTGTACAGAGTACATTGATCTATATTTT
TTCCACTTTCCCGTTTCATTTCGCTATCGAAGCGATGAGGAGAAATGGCCTTTGTCACCT
GATGATTGCCTTGATAATGACTATATGAATGCATGGTGGGATATGGAAAAACTTGTGGAT
ATGGGATTAGTGAGATATATTGGCTTGTCAAACTTTAATGCGCAGCAGATTCAAGGAGTT
TACGATATTTCAAAAAAGCATAAGCCCGTTTGTAACGAACTAGAACACAATCCTGGCTAC
TCAAATGATGAATTGTTAAAGTTGCACAAAAAACTAAACATTCAAATGCTCGCTTATTGT
CCCCTTGGACGTGCAAAGGAAGAAAAATTAGAACCAAAATTTCTATATGATGAGAAAGTT
AAAAAAATCGCGAAAAAGTATCATAAATCATCATCACAAATTGCTTTACGATATTCAATA
CAATGCGATTTGATTCCCATACCGAAATCAACTAAAAATAATCATATTCGAGAGAACATA
AATGTCTTTGATTTTCAATTGAATGATGATGAAATGCAATATATGAAAACTTTTCATAAT
GACGCAAATCAAATTTGTAAATTTCATTTTGCAGAAGGAAATATTCATTATCCATTTTGA
>g1988.t1 Gene=g1988 Length=279
MFRLLNNLTIPFIGMGTGKLKGELGVTAIKEAIDAGYRLFDTAFLYDNENILWGIHHDQV
ERACRDSCKRLCTEYIDLYFFHFPVSFRYRSDEEKWPLSPDDCLDNDYMNAWWDMEKLVD
MGLVRYIGLSNFNAQQIQGVYDISKKHKPVCNELEHNPGYSNDELLKLHKKLNIQMLAYC
PLGRAKEEKLEPKFLYDEKVKKIAKKYHKSSSQIALRYSIQCDLIPIPKSTKNNHIRENI
NVFDFQLNDDEMQYMKTFHNDANQICKFHFAEGNIHYPF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g1988.t1 | Gene3D | G3DSA:3.20.20.100 | - | 1 | 51 | 2.6E-11 |
| 12 | g1988.t1 | Gene3D | G3DSA:3.20.20.100 | - | 52 | 279 | 1.6E-65 |
| 2 | g1988.t1 | PANTHER | PTHR11732:SF482 | ZGC:56622 | 4 | 51 | 2.1E-58 |
| 4 | g1988.t1 | PANTHER | PTHR11732 | ALDO/KETO REDUCTASE | 4 | 51 | 2.1E-58 |
| 3 | g1988.t1 | PANTHER | PTHR11732:SF482 | ZGC:56622 | 56 | 278 | 2.1E-58 |
| 5 | g1988.t1 | PANTHER | PTHR11732 | ALDO/KETO REDUCTASE | 56 | 278 | 2.1E-58 |
| 14 | g1988.t1 | PIRSF | PIRSF000097 | AKR | 1 | 54 | 2.4E-11 |
| 15 | g1988.t1 | PIRSF | PIRSF000097 | AKR | 50 | 279 | 4.5E-55 |
| 7 | g1988.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 32 | 56 | 3.2E-26 |
| 6 | g1988.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 115 | 132 | 3.2E-26 |
| 9 | g1988.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 150 | 179 | 3.2E-26 |
| 8 | g1988.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 194 | 218 | 3.2E-26 |
| 1 | g1988.t1 | Pfam | PF00248 | Aldo/keto reductase family | 53 | 256 | 1.7E-32 |
| 11 | g1988.t1 | ProSitePatterns | PS00062 | Aldo/keto reductase family signature 2. | 115 | 132 | - |
| 10 | g1988.t1 | SUPERFAMILY | SSF51430 | NAD(P)-linked oxidoreductase | 6 | 264 | 1.01E-66 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0047834 | D-threo-aldose 1-dehydrogenase activity | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed