Gene loci information

Transcript annotation

  • This transcript has been annotated as Somatostatin receptor type 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g1995 g1995.t1 isoform g1995.t1 14323832 14326587
chr_3 g1995 g1995.t1 exon g1995.t1.exon1 14323832 14324309
chr_3 g1995 g1995.t1 cds g1995.t1.CDS1 14323832 14324309
chr_3 g1995 g1995.t1 exon g1995.t1.exon2 14324376 14324464
chr_3 g1995 g1995.t1 cds g1995.t1.CDS2 14324376 14324464
chr_3 g1995 g1995.t1 exon g1995.t1.exon3 14325325 14325766
chr_3 g1995 g1995.t1 cds g1995.t1.CDS3 14325325 14325766
chr_3 g1995 g1995.t1 exon g1995.t1.exon4 14326051 14326260
chr_3 g1995 g1995.t1 cds g1995.t1.CDS4 14326051 14326260
chr_3 g1995 g1995.t1 exon g1995.t1.exon5 14326328 14326587
chr_3 g1995 g1995.t1 cds g1995.t1.CDS5 14326328 14326587
chr_3 g1995 g1995.t1 TSS g1995.t1 NA NA
chr_3 g1995 g1995.t1 TTS g1995.t1 NA NA

Sequences

>g1995.t1 Gene=g1995 Length=1479
ATGAATACGTTCGAAGATTCAGCAACGAGGTCATTTTTTTATGATGGTCCCTCATTTGAT
TTTTTGATGTCATCAGACTTTCCAAACACATCATCTATAACTTATCAAAATAACGATCCG
CATGGAAATGAAACAATGTTCATGAGCTGCCATTCAGGCGGACCCAATAATCTTGGTCGT
TACATATCGATGATACTATTCACAGTTGTGTGCATTGTTGGACTTTTTGGAAATAGTTTA
GTGATATATGTTGTATTACGATTCAGCAAAATGAAAACGGTAACAAATTTGTACATTCTG
AATCTCGCGTTGGCTGATGAATTTTTTTTGATTGGAGTTCCGACACTCATTTACACTATG
CAAGTGGGTGAATGGATTTTTGGGGAGCAGCTTTGTAAACTATATATGATATCGACGAGC
ATAACACAATTTACATCATCAATTTTCCTAGTCATCATGTCGGCTGATAGATTTATTGCT
GTTTGTCATCCAATTTCCTCGCCTCGCTTTCGCACACCACTAGTTTCAAAAATTGTCTCG
TTGATTGCATGGTGCTTATCCGTTATCATGATGCTTCCAATCATCCTCTATTCAACAACA
ATTCCTCGACCTGATGGTAAAAAGACTTGTAATATTGTATGGCCTACGAGCAATACACGA
TCAAATGGAACATCATCAGAGGAAGATGGCTTAATTGAGCCAAATGGATCAACATTTACT
CTATATACCTTCACAATGGGTTTCGCAATTCCACTCTGTCTTATCCTGATCTTCTATTAT
CTAGTTTTGCGTAAACTTAGAACAGTTGGACCGAAAACAAAGTCAAAGGAAAAGAAGAGA
TCACATCGTAAAGTAACGAAGCTTGTTCTGACTGTCATTGCTGTGTATATCCTTTGTTGG
ACCCCATACTGGGTTAGTCAAATGGCATTAATAAATTCATCGCCTGAGGTCTGCCAGTCA
AAGTTAGAAATCACAATTTTCATTCTTGTCGGCTGTTTAGGCTATTCAAACTCTAGTATG
AATCCAGTGCTCTACGCTTTTCTATCAGATAATTTTAAGAAATCATTTATGAAGGCATTC
ACTTGTGCCAAGACCAAAGAAATCAATGCACAATTGCAAGCTGAAAACAGCTTCTTTCCA
CGATTTGGTCGTAATCGCAATTCAGAATGCATTTCATCGAAACCAACAACCAATCTTATT
GTGAATGCGAATTCACAAATTACATCAACTAAACTTGCATCAACAAAACTCGGTAATACA
GTTGAGTCGATATTAGATGCGACTGAGAATGGACATACAACAACAGCAACAAATGGACAT
CAATTGAATAACATCAACAAGCTCTGCATCAAAACAAGTGATGAGGAAAGCGATGACGAA
CAAGAGATGCAGGACAAGCACGATGAATCCATTTGCATAATAAATCCTAGTAATGGAACA
CATCATAGTAAACCACCAGTATTACACACAGATCTATAA

>g1995.t1 Gene=g1995 Length=492
MNTFEDSATRSFFYDGPSFDFLMSSDFPNTSSITYQNNDPHGNETMFMSCHSGGPNNLGR
YISMILFTVVCIVGLFGNSLVIYVVLRFSKMKTVTNLYILNLALADEFFLIGVPTLIYTM
QVGEWIFGEQLCKLYMISTSITQFTSSIFLVIMSADRFIAVCHPISSPRFRTPLVSKIVS
LIAWCLSVIMMLPIILYSTTIPRPDGKKTCNIVWPTSNTRSNGTSSEEDGLIEPNGSTFT
LYTFTMGFAIPLCLILIFYYLVLRKLRTVGPKTKSKEKKRSHRKVTKLVLTVIAVYILCW
TPYWVSQMALINSSPEVCQSKLEITIFILVGCLGYSNSSMNPVLYAFLSDNFKKSFMKAF
TCAKTKEINAQLQAENSFFPRFGRNRNSECISSKPTTNLIVNANSQITSTKLASTKLGNT
VESILDATENGHTTTATNGHQLNNINKLCIKTSDEESDDEQEMQDKHDESICIINPSNGT
HHSKPPVLHTDL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
32 g1995.t1 CDD cd15094 7tmA_AstC_insect 62 356 4.76271E-145
16 g1995.t1 Gene3D G3DSA:1.20.1070.10 - 33 378 1.9E-81
2 g1995.t1 PANTHER PTHR24229:SF51 ALLATOSTATIN C RECEPTOR 1-RELATED 31 389 1.7E-142
3 g1995.t1 PANTHER PTHR24229 NEUROPEPTIDES RECEPTOR 31 389 1.7E-142
14 g1995.t1 PRINTS PR00246 Somatostatin receptor signature 59 71 8.7E-8
7 g1995.t1 PRINTS PR00237 Rhodopsin-like GPCR superfamily signature 62 86 1.9E-46
4 g1995.t1 PRINTS PR00237 Rhodopsin-like GPCR superfamily signature 95 116 1.9E-46
10 g1995.t1 PRINTS PR00237 Rhodopsin-like GPCR superfamily signature 139 161 1.9E-46
5 g1995.t1 PRINTS PR00237 Rhodopsin-like GPCR superfamily signature 175 196 1.9E-46
9 g1995.t1 PRINTS PR00237 Rhodopsin-like GPCR superfamily signature 240 263 1.9E-46
11 g1995.t1 PRINTS PR00246 Somatostatin receptor signature 264 273 8.7E-8
12 g1995.t1 PRINTS PR00246 Somatostatin receptor signature 274 287 8.7E-8
6 g1995.t1 PRINTS PR00237 Rhodopsin-like GPCR superfamily signature 285 309 1.9E-46
8 g1995.t1 PRINTS PR00237 Rhodopsin-like GPCR superfamily signature 327 353 1.9E-46
13 g1995.t1 PRINTS PR00246 Somatostatin receptor signature 347 359 8.7E-8
1 g1995.t1 Pfam PF00001 7 transmembrane receptor (rhodopsin family) 77 345 1.2E-52
23 g1995.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 60 -
29 g1995.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 61 86 -
18 g1995.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 87 97 -
30 g1995.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 98 122 -
22 g1995.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 123 133 -
25 g1995.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 134 153 -
17 g1995.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 154 173 -
31 g1995.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 174 197 -
21 g1995.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 198 238 -
28 g1995.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 239 263 -
19 g1995.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 264 283 -
27 g1995.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 284 304 -
24 g1995.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 305 323 -
26 g1995.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 324 348 -
20 g1995.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 349 492 -
41 g1995.t1 ProSitePatterns PS00237 G-protein coupled receptors family 1 signature. 145 161 -
42 g1995.t1 ProSiteProfiles PS50262 G-protein coupled receptors family 1 profile. 77 345 44.585
40 g1995.t1 SMART SM01381 7TM_GPCR_Srsx_2 71 360 1.1E-5
15 g1995.t1 SUPERFAMILY SSF81321 Family A G protein-coupled receptor-like 24 367 3.94E-70
37 g1995.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 62 84 -
35 g1995.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 97 119 -
33 g1995.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 134 153 -
36 g1995.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 174 196 -
38 g1995.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 241 263 -
34 g1995.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 289 311 -
39 g1995.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 326 348 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0007186 G protein-coupled receptor signaling pathway BP
GO:0016021 integral component of membrane CC
GO:0004994 somatostatin receptor activity MF
GO:0004930 G protein-coupled receptor activity MF

KEGG

Orthology

Pathway

This gene does not belong to any pathways.

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed