Gene loci information

Transcript annotation

  • This transcript has been annotated as Head-specific guanylate cyclase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2124 g2124.t2 isoform g2124.t2 15338909 15340126
chr_3 g2124 g2124.t2 exon g2124.t2.exon1 15338909 15339132
chr_3 g2124 g2124.t2 cds g2124.t2.CDS1 15338909 15339132
chr_3 g2124 g2124.t2 exon g2124.t2.exon2 15339189 15340126
chr_3 g2124 g2124.t2 cds g2124.t2.CDS2 15339189 15340125
chr_3 g2124 g2124.t2 TSS g2124.t2 NA NA
chr_3 g2124 g2124.t2 TTS g2124.t2 NA NA

Sequences

>g2124.t2 Gene=g2124 Length=1162
ATGACTTGTCCATTCGTACAAAGAAAGCCAGTCGATGCATTTCAACGACAACAGTCGACT
GTTGCAGATTTTGACTTACAAGACATTAACGACGATTCATTAAACCTGAAGCACATTAAC
GAAGCTTTGCAGCTTTTGACTGCACCAAGCAATCAGGCAATTAATCAGGCATTGCAATCT
CTCACTGAGAAATATGGCGAAAAATATCCTATTTTAGTAAAACTCGTTGAAGAGAAGAAT
AATATTTCATCGTTTCCAAATTATGACTATTTAGCTGACATACAAAATGCATTAATGGAA
GTCGATGAAGCGACAGTTGTTGATGTGTTGGTTTTATTGGGCGAAGAATTAATTGAGACA
TCATGCAAAGGAATTATCGAGAAAGCTTTTAAAAGTCTCGGTCAAAATATGAAAGAAATG
ATAGCATCCCTTGATGGTGTTTACGATGTATTGAAATTACAAGAAGAAGATTTAACTGAC
GCTGGTTTTATTGCGTCCGAGAATGAATTAATTTTCACATCAGATCGAATGTGTGTCGCT
TATGTATTACTTGGCATTTTGCAGCGTTTATCGAAGAAATTATATGGAGAACATAGTGTC
ATCACTATGGAAGTAATTGAGGGCAGCGTTCAAAAATTTCGTTATTTATTCAGCATAACT
GAAGAAGAGAAACCTGAAGCCCCAACACGTGAAATATCGTCTGATCCCAAAGATTTGTTG
ATGTCAAATAAGACTTACTGCAAAATGTTTCCTTGGCACTTTATTTTTGATGAAAGTCTA
GATTTAATCCAAGTCGGAGCTGCTTTTACAAAACTTTTCAAAAATTATTTGAAAACAACT
AAATCTGTTACAAATTTCTTTCGTTTTAAACGACCAGTTGGATTAAAACTTGAGTTTGAT
GAGATAGCAAAACGCACAAATACTCCATTTTTGCTTTCACTTCGTTCATCACGGCCAGAC
TTTGTTGCAAAAGGTTTGGAAATTAAGGGACAAATGGTTCTATGTAAGAACAGTAATCGA
AAAACTCTCATGTTTATTGGCTCACCTTCTTTAGATGGTTTAGAAGGACTGACATGCAAT
GGTCTCTTCTTATCAGATATTCCTATTTTTGATGCGACACGCGAAGTTATTTTAGTCGGA
GAACAAGCGAGAGCTCAAGATG

>g2124.t2 Gene=g2124 Length=387
MTCPFVQRKPVDAFQRQQSTVADFDLQDINDDSLNLKHINEALQLLTAPSNQAINQALQS
LTEKYGEKYPILVKLVEEKNNISSFPNYDYLADIQNALMEVDEATVVDVLVLLGEELIET
SCKGIIEKAFKSLGQNMKEMIASLDGVYDVLKLQEEDLTDAGFIASENELIFTSDRMCVA
YVLLGILQRLSKKLYGEHSVITMEVIEGSVQKFRYLFSITEEEKPEAPTREISSDPKDLL
MSNKTYCKMFPWHFIFDESLDLIQVGAAFTKLFKNYLKTTKSVTNFFRFKRPVGLKLEFD
EIAKRTNTPFLLSLRSSRPDFVAKGLEIKGQMVLCKNSNRKTLMFIGSPSLDGLEGLTCN
GLFLSDIPIFDATREVILVGEQARAQD

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g2124.t2 Gene3D G3DSA:3.90.1520.10 - 51 226 9e-07
6 g2124.t2 Gene3D G3DSA:3.30.450.260 - 241 367 0e+00
4 g2124.t2 PANTHER PTHR45655:SF6 HEAD-SPECIFIC GUANYLATE CYCLASE 94 387 0e+00
5 g2124.t2 PANTHER PTHR45655 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 94 387 0e+00
1 g2124.t2 Pfam PF07700 Haem-NO-binding 79 201 0e+00
2 g2124.t2 Pfam PF07701 Heme NO binding associated 241 317 0e+00
3 g2124.t2 Pfam PF07701 Heme NO binding associated 324 386 0e+00

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006182 cGMP biosynthetic process BP
GO:0020037 heme binding MF
GO:0004383 guanylate cyclase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed