Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Protein phosphatase 1B.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2337 g2337.t6 TTS g2337.t6 16896666 16896666
chr_3 g2337 g2337.t6 isoform g2337.t6 16896837 16899715
chr_3 g2337 g2337.t6 exon g2337.t6.exon1 16896837 16897292
chr_3 g2337 g2337.t6 cds g2337.t6.CDS1 16897223 16897292
chr_3 g2337 g2337.t6 exon g2337.t6.exon2 16897364 16897466
chr_3 g2337 g2337.t6 cds g2337.t6.CDS2 16897364 16897466
chr_3 g2337 g2337.t6 exon g2337.t6.exon3 16899432 16899549
chr_3 g2337 g2337.t6 cds g2337.t6.CDS3 16899432 16899549
chr_3 g2337 g2337.t6 exon g2337.t6.exon4 16899606 16899715
chr_3 g2337 g2337.t6 cds g2337.t6.CDS4 16899606 16899707
chr_3 g2337 g2337.t6 TSS g2337.t6 NA NA

Sequences

>g2337.t6 Gene=g2337 Length=787
GGGATGTGATGAGTAACGAGGCCGTCTGTAATTTTGTTCATAATCGCCTTCGAATTTCTG
ATGACTTGGTGTGGATTTGTAATCAAGTTATTGACACATGCTTGCACAAGGGTTCTCGCG
ATAATATGAGCATCATTCTAATAGTATTCCCCGGAGCGCCGAAACCTTCCAGTGAAGCTA
TTGAAGCAGAAGAGGAGCTTGAGAGGAATATACGTAAAACTATAAAAGAATTCACAGAAA
ATACGGAGGCTGCATACGATGTGAGTTCATTAATGCGCTTATTAGCCAGCAGTAACATTC
AGTGGCCGGAAGGTGGTGGTATAGAATCTAAATATAAACTTATTACGGAAGTATTTAAGG
AAATCTGTCCTGATCTCACTGATGCAGAATTCGAGTTTTAAAGAAAACCCTTTTTTACAA
TAGAATATTGATTATGATTTTCTTTGATAAAAAAAAACAACCTTTGATACAATTATTCAG
CCAAATAACTATTGGAACAATATTTCAAACTACTATTTCAAATGAAGAAGAAAATAAGAA
ATGAGTAAAAATGATATCCGTGATTACAAATGAAGTAGAAATAAGCTGTTCTAATTTCCA
TCTTAAAATATTGTACATAAATTTTACTTAAATTTCCTCTTAAATATTCTAATTTTGACG
ATTTTTTTTACAATGAAATTCTTTTCCATCAACTTTTTTTTTCTTAAAATAAAATCAAAT
TTACACTTTTACAAACATACGCCAGTTTCTATTTTATGCGTGTGTAATTAAATATTTAAT
GATGAGA

>g2337.t6 Gene=g2337 Length=130
MSNEAVCNFVHNRLRISDDLVWICNQVIDTCLHKGSRDNMSIILIVFPGAPKPSSEAIEA
EEELERNIRKTIKEFTENTEAAYDVSSLMRLLASSNIQWPEGGGIESKYKLITEVFKEIC
PDLTDAEFEF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g2337.t6 Coils Coil Coil 54 78 -
7 g2337.t6 Gene3D G3DSA:3.60.40.10 Phosphatase 2c; Domain 1 1 54 4.2E-11
6 g2337.t6 Gene3D G3DSA:1.10.10.430 Phosphatase 2C; domain 2 55 122 3.1E-14
2 g2337.t6 PANTHER PTHR47992:SF121 PROTEIN PHOSPHATASE 1A 1 97 4.4E-17
3 g2337.t6 PANTHER PTHR47992 ALPHABET, ISOFORM E-RELATED 1 97 4.4E-17
1 g2337.t6 Pfam PF07830 Protein serine/threonine phosphatase 2C, C-terminal domain 41 117 4.7E-24
4 g2337.t6 SUPERFAMILY SSF81606 PP2C-like 1 49 1.96E-9
5 g2337.t6 SUPERFAMILY SSF81601 Protein serine/threonine phosphatase 2C, C-terminal domain 53 121 5.75E-12

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0000287 magnesium ion binding MF
GO:0004721 phosphoprotein phosphatase activity MF
GO:0030145 manganese ion binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values