General information for g2379.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Brefeldin A-inhibited guanine nucleotide-exchange protein 2.
Parent gene
- The parent gene g2379 is located on chr_3: 17468175..17469184 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2379 | g2379.t1 | TTS | g2379.t1 | 17463120 | 17463120 |
| chr_3 | g2379 | g2379.t1 | isoform | g2379.t1 | 17463253 | 17468960 |
| chr_3 | g2379 | g2379.t1 | exon | g2379.t1.exon1 | 17463253 | 17463384 |
| chr_3 | g2379 | g2379.t1 | cds | g2379.t1.CDS1 | 17463253 | 17463384 |
| chr_3 | g2379 | g2379.t1 | exon | g2379.t1.exon2 | 17463457 | 17468181 |
| chr_3 | g2379 | g2379.t1 | cds | g2379.t1.CDS2 | 17463457 | 17468181 |
| chr_3 | g2379 | g2379.t1 | exon | g2379.t1.exon3 | 17468292 | 17468692 |
| chr_3 | g2379 | g2379.t1 | cds | g2379.t1.CDS3 | 17468292 | 17468692 |
| chr_3 | g2379 | g2379.t1 | exon | g2379.t1.exon4 | 17468828 | 17468960 |
| chr_3 | g2379 | g2379.t1 | cds | g2379.t1.CDS4 | 17468828 | 17468960 |
| chr_3 | g2379 | g2379.t1 | TSS | g2379.t1 | 17469214 | 17469214 |
Sequences
>g2379.t1 Gene=g2379 Length=5391
ATGCAAAATTACCCCAATAAAACAAAAGAAATGTTCATAGTACGAGCTTTAGAGAAAATT
CTTGCAGACAAGGATATCAAACGACAGGGTCAGCTAAAAAAAGCATGTGAGTCGGCAATA
ACTACTCTGAAAGAAGAACTAAAGGAAGAAAATGGACAAATTCCGACAAATAATGATCAA
CAACAACAACATTCTTCAGCTGCTTTGCCTCTTCCTAAAAATGATTCTACAAACAGCATA
AATGCAGAGAAATATTTTCTACCTTTTGAATTAGCATGTCAGAGTAAAACACCTCGTATC
GTTGTAACAGCTCTCGATTGTTTACAAAAATTGATTGCTTATGGTCATTTAACTGGAAAT
ATTCCTGACTCCGCTAATCCTGGAAAGTTTCTTATCGATAGAATCGTAACGACAATATGC
AATTGTTTTATGGGCCCCCAAACAGATGAAGGCGTTCAACTTCAAATTATTAAGGCACTT
CTCACTGTAGTAACATCGCAAAATGTTGAAGTTCATGAAGGCACCGTTCTACAAGCTGTG
CGAACATGCTATGACATTTATTTATCAAGTAAAAATTTGATAAACCAGACGACCGCACGA
GCAACGTTGACTCAAATGCTGAATGTAATATTTACTCGTATGGAAAATCAAGCATTTGAA
TCTACATGCATTCCAGTTCCAAATCAAAATAATATCAATAACGCTCTATCATCAACGACA
CCTAATAACTCACAAAGTGACGAAAAATCACCGACGATAAATAATCATGAAAGTGAATTG
AAATCAGCTTCAGAAATTAATAATGAAGTCAAAGGTGAAGAATGTGAAAATAAGAATGAT
AATATTGCATCAAAAGTTAATGAACAGCAGACATTGGAAATGAATGAGAATGAAAATATG
AAAGATTATGTGCGTAAATTTGTTGACGAAATATTGGATAATGCTGTTGACATTGTAGAG
AATAAATTAAGCAACGGTGGAAGTAGCAATAATCATATATTAAACAATAATAGTAATAGT
GAAGAAAATGAAAAAGTTGACACTGATAATAAATCAGAGGAATTAAAGAAGGTTTCGAGT
GTTAGTAGTATTTCAAATGATGGATCAACAGATCATCCTCCTTCACATGAAAGTGCCGAG
ATAAGTTCAGAAAATGAAAATATTGCTGCTGCAAAATTCACACATGTATTACAGAAAGAT
GCCTTTCTAGTGTTTCGAGCACTTTGCAAGTTATCAATGAAACCATTACCAGAAGGACAA
CCAGATCCAAAGTCACATGAGTTGCGATCAAAAATTCTCTCATTACATCTCTTACTCTCC
ATTCTTCAAAATGCTGGTCCAGTTTTTCGATCAAATGAAATGTTTATAATGGCCATCAAA
CAATACTTATGCGTGGCATTGTCAAAGAATGGTGTCAGTTCCGTCCCAGAAATTTTTGAG
CTGTCATTGTCTATATTCGTGGCCTTATTATCGAATTTTAAGGTTCATTTGAAGAAGCAA
ATTGAAGTATTTTTCAAAGAGATTTTCCTCAACATACTTGAGACAGCGAGCTCAACTTTT
GAACATAAATTCATGGTAATTCAAGCTTTAGTGAGAATCTGTGCTGATGCTCAAAGTGTC
GTTGACATCTATATAAATTATGATTGTGATTTTTCTGCAGCAAATTTATTTGAGAGACTC
GTCAACGATTTGTCAAAAATCGCTCAAGGGCGGCAGGCATTAGAATTGGGAGCAACAACA
GTTCAAGAAAAATCAATGCGTATAAAAGGACTTGAATGTCTCGTCTCAATTCTCAAATGT
AAAGTTGAATGGAGTAAAGATTTATATATGAATCCAAATCTTCAAACATCACTAGGTGAA
ACTACACATAAAAGTACTAATATCACAACTGAGCCTGATACGAGCGACCAGCAGTCTATA
AAACATAGTGGTTCGAGCTTAAGCTTGAATTCTTCAAGTAGTGTCAATAATAATTCTGGT
AATAAAGAAGTTTTAGATTTTCCTGAAGAACTTGAAGAGAGAAAACAAAGAAAAGAATTG
ATGGAAACTGGAATTGAGATGTTTAACAAGAAACCAAAAAAGGGAATTCAATTTTTGCAA
GAGAGAGGTCTTTGTGGATTACGTATAGAAGATATTGCAAAATTCCTAATTGAAGATGAT
CGTTTAGATAAAACGCAAGTCGGTGATTTTCTTGGCGATAATGATGAACTAAGCAAATCT
GTTATGTGTGCTTATATTGATGCAAAAGATTTTAGTGGAATGGAAATTGTAGCAGCGTTG
AGATTCTTTCTTGAAGGTTTTCGTTTGCCTGGTGAAGCACAAAAAATTGATAGACTTATG
GAAAAGTTTGCGAGTCGATATTGCGAATGTAATCCAAATAATCAGCTTTTTACAAGTGCT
GATACTGTCTACGTTCTCGCCTTTTCAATCATCATGTTGACAACTGACCTACACTCACCA
CAAGTTAAAAATAAAATGAGCAAAGAACAATATATTAAATTGAATCGAGGAATAAGTGAC
AGTAAAGATCTACCTGAGGAATATCTATCACAAATTTATGATGAAATTTCCGATCAAGAA
ATCAAAATGAAGAATACGGTCGTCAATAAACCAAGTAATAAACAAGTTTTTATTAATGAA
AAAAAGCGTAAATTGTTATGGAATATGGAAATGGAAGCAATTTCATCAACAGCAAAAAAT
CTTATGGAATCAGTTTCACATGTTCGTGAAGCATTTACATCAGCTAAACATTTAGATCAT
GTTCGTCCAATGTTTAAACTTTCATGGACTCCCTTTTTAGCAGCCTTTTCAGTTGGTCTG
CAGGACTGTGATGATCCTGAAATTGCAATGTTATGTTTAGATGGTATTCGATGCGCAATA
AGGATTGCATGTATTTTTCACATGACACTTGAACGCGATGCTTATGTTCAAGCACTTGCT
CGATTTACATTATTGACAGCAAATTCTCCAATTACAGAGATGAAAGCAAAGAACATTGAT
ACGATAAAGACATTAATAATGGTTGCTCATACAGATGGAAATTATTTAGGTACAAGTTGG
TTAGATATTGTAAAATGCATATCGCAATTGGAGCTTGCTCAATTGATTGGAACTGGTGTC
AGACCGCAATACCTTTCTGGACCTACTCATCGTGATGCACTGCTAGATCCGAGTGTCAAA
GAGCATATTGGCGAGACGAGTTCCCAATCGGTCGTTGTTGCAGTTGATAGAATTTTTACT
GGCTCAATTCGACTCGATGGAGATGCAATAGTAGATTTTGTTAAAGCACTCTGTCATGTT
TCACTTGATGAACTGAATAATCCACAACCGAGAATGTTTTCGCTTCAAAAAATTGTTGAA
ATCTCTTACTACAACATGGGAAGAATTAGGTTACAATGGTCAAGAATTTGGCAAGTGCTT
GGTGACTATTTCAACACAGTCGGTTCGTATGCAAATGAAGAGATTGCATTCTTTGCGCTT
GATTCGCTTCGTCAGCTATCAATGAAATTCATTGAAAAAGGAGAATTTACAAACTTTCGC
TTTCAAAAAGATTTTTTGCGTCCATTCGAGCATATAATGAAGAAAAATAATTCACCAGCG
ACAAGAGACATGGTTGTACGGTGTGTTGCTCAAATGGTAAATTCACAGTCACAAAATATC
AAATCAGGATGGAAAAATATTTTCTCAGTCTTTCATCTTGCTGCTGGAGACAATGATGAA
TCTATTGTTGAGTTGGCATTTCAAACAACAGGAAAGATTATCACGGTGCTATATAAGAAA
CAGTTTCATATAATGATTGATTCATTTCCTGATGCTGTCAAATGTCTTTCTGAATTTGCA
TCAAATGCACGCTTTCCTGACATATCAATGGAAGCAATTCGTCTATTAAGAACTTGTGCT
GTTTCAGTTAATGAGTCACCACAGCAATTTGCGGATCATACAGGAATGGAAAATGATATT
CATGTGCTTGAAGAGGATCGTGTATGGGTTCGAGGATGGTTTCCTATGCTTTTCTCTCTT
TCATGTGTTGTAAATCGATGCAAACTTGATGTGAGAACGAGAGCACTTACTGTATTGTTT
GAGATAGTCAAAACATATGGTGAAAGTTATAAGCCCAATTGGTGGCGTGATTTATTCAAT
ATTTTATTTAGAATTTTTGACAATATGAAACTTCCTGAACATCACACCGAAAAGGCAGAA
TGGATGACTACAACTTGTAATCATGCTTTGTATGCAATAATTGACGTTTTTACGCAATAT
TTTGATACTCTTGGTCCATTGTTGCTTAAAGATTTATACAGTCAATTGCAGTGGTGTGTA
CAACAGAATAATGAACAACTGGCACGTAGTGGCACAAATTGTCTAGAGAATTTGGTAATT
TCAAATGGAACAAAGTTCAATATGGATACATGGGAAGATACAGCATGCTGTATATTAGAT
ATCTTTAAGCAAACTCTTCCGCATGAGTTGCAAACATGGAAACCCGATCCAAATCAATTG
CAATCACCAACTTCACCATTATCACCGACTGGACAAACAAATTTAAATTCACAGCATCGA
CATTCGATAGAAAATGGCGAAGTTCGTCATGGCATTCTTAAACGTAGTAATTCACAACAT
TCCGTTTATAGTCTTAATTCCGAAGATGGCAAGACTGAGCTTATCATGCATACGAGTGGA
CTCTTTTCTAGTTTATTAATCAAATGTGTTGTACAATTAGAACTTATTCAAACAATCGAC
AATATCATTTTCTTCCCAGCTACAACAAAGAAAGAAGATGCAGAAACATTAGCACTTGCA
ACTGCTGATTTAAATCAGAGTGGTAACATTTCATTACTATCAACAGGTGAACATACCGAA
TGTCAGCGTGAAGACCAAGGAATGTACAGCTTCTTAAGTACAGTTCATCTGATAAAATTT
GTTGATTGTCTTGTTGAAAGTCATCGTTTTGCAAAAAGTTTTAATCAAAATAATGATCAG
CGGATGTTGCTCTGGAAAGCTGGTTTTAAAGGCTCAGTCAAGCCAAATCTTATGAAACAA
GAAACACAATCGTTAGCGTGTGTATTAAGAATTTTATTTAAAATGTATAGTGATGAAAAT
CGACGAGATGATTGGGTGGAGATCGAGCAGAGATTGATAAGTGTATGCAAAGAGGCACTT
GAGTACTTTTTAGCGCTTCAAAGTGAACCACATCGTGAGGCATGGACATCTTTATTGCTT
CTCATCATGACACGATTACTAAAAATGCCAGATCAGAGATTCGCAACACATTCTGCAAAT
TACTATCCATTATTCTGTGACATGATGTGCTACGATATGAAACCAGAACTCAGAAGTGTA
CTTAGAAGATTGTTTGTGCGCATCGGTCCTGTCTTTGGCATCAATAGTTAA
>g2379.t1 Gene=g2379 Length=1796
MQNYPNKTKEMFIVRALEKILADKDIKRQGQLKKACESAITTLKEELKEENGQIPTNNDQ
QQQHSSAALPLPKNDSTNSINAEKYFLPFELACQSKTPRIVVTALDCLQKLIAYGHLTGN
IPDSANPGKFLIDRIVTTICNCFMGPQTDEGVQLQIIKALLTVVTSQNVEVHEGTVLQAV
RTCYDIYLSSKNLINQTTARATLTQMLNVIFTRMENQAFESTCIPVPNQNNINNALSSTT
PNNSQSDEKSPTINNHESELKSASEINNEVKGEECENKNDNIASKVNEQQTLEMNENENM
KDYVRKFVDEILDNAVDIVENKLSNGGSSNNHILNNNSNSEENEKVDTDNKSEELKKVSS
VSSISNDGSTDHPPSHESAEISSENENIAAAKFTHVLQKDAFLVFRALCKLSMKPLPEGQ
PDPKSHELRSKILSLHLLLSILQNAGPVFRSNEMFIMAIKQYLCVALSKNGVSSVPEIFE
LSLSIFVALLSNFKVHLKKQIEVFFKEIFLNILETASSTFEHKFMVIQALVRICADAQSV
VDIYINYDCDFSAANLFERLVNDLSKIAQGRQALELGATTVQEKSMRIKGLECLVSILKC
KVEWSKDLYMNPNLQTSLGETTHKSTNITTEPDTSDQQSIKHSGSSLSLNSSSSVNNNSG
NKEVLDFPEELEERKQRKELMETGIEMFNKKPKKGIQFLQERGLCGLRIEDIAKFLIEDD
RLDKTQVGDFLGDNDELSKSVMCAYIDAKDFSGMEIVAALRFFLEGFRLPGEAQKIDRLM
EKFASRYCECNPNNQLFTSADTVYVLAFSIIMLTTDLHSPQVKNKMSKEQYIKLNRGISD
SKDLPEEYLSQIYDEISDQEIKMKNTVVNKPSNKQVFINEKKRKLLWNMEMEAISSTAKN
LMESVSHVREAFTSAKHLDHVRPMFKLSWTPFLAAFSVGLQDCDDPEIAMLCLDGIRCAI
RIACIFHMTLERDAYVQALARFTLLTANSPITEMKAKNIDTIKTLIMVAHTDGNYLGTSW
LDIVKCISQLELAQLIGTGVRPQYLSGPTHRDALLDPSVKEHIGETSSQSVVVAVDRIFT
GSIRLDGDAIVDFVKALCHVSLDELNNPQPRMFSLQKIVEISYYNMGRIRLQWSRIWQVL
GDYFNTVGSYANEEIAFFALDSLRQLSMKFIEKGEFTNFRFQKDFLRPFEHIMKKNNSPA
TRDMVVRCVAQMVNSQSQNIKSGWKNIFSVFHLAAGDNDESIVELAFQTTGKIITVLYKK
QFHIMIDSFPDAVKCLSEFASNARFPDISMEAIRLLRTCAVSVNESPQQFADHTGMENDI
HVLEEDRVWVRGWFPMLFSLSCVVNRCKLDVRTRALTVLFEIVKTYGESYKPNWWRDLFN
ILFRIFDNMKLPEHHTEKAEWMTTTCNHALYAIIDVFTQYFDTLGPLLLKDLYSQLQWCV
QQNNEQLARSGTNCLENLVISNGTKFNMDTWEDTACCILDIFKQTLPHELQTWKPDPNQL
QSPTSPLSPTGQTNLNSQHRHSIENGEVRHGILKRSNSQHSVYSLNSEDGKTELIMHTSG
LFSSLLIKCVVQLELIQTIDNIIFFPATTKKEDAETLALATADLNQSGNISLLSTGEHTE
CQREDQGMYSFLSTVHLIKFVDCLVESHRFAKSFNQNNDQRMLLWKAGFKGSVKPNLMKQ
ETQSLACVLRILFKMYSDENRRDDWVEIEQRLISVCKEALEYFLALQSEPHREAWTSLLL
LIMTRLLKMPDQRFATHSANYYPLFCDMMCYDMKPELRSVLRRLFVRIGPVFGINS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g2379.t1 | CDD | cd00171 | Sec7 | 677 | 861 | 7.29383E-87 |
| 15 | g2379.t1 | Coils | Coil | Coil | 33 | 53 | - |
| 14 | g2379.t1 | Coils | Coil | Coil | 253 | 273 | - |
| 13 | g2379.t1 | Gene3D | G3DSA:1.10.220.20 | - | 669 | 751 | 1.7E-29 |
| 12 | g2379.t1 | Gene3D | G3DSA:1.10.1000.11 | - | 752 | 869 | 6.0E-51 |
| 23 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 49 | 74 | - |
| 19 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 53 | 74 | - |
| 18 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 239 | 282 | - |
| 22 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 239 | 261 | - |
| 24 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 262 | 281 | - |
| 25 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 329 | 383 | - |
| 20 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 342 | 356 | - |
| 27 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 357 | 372 | - |
| 21 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 627 | 663 | - |
| 26 | g2379.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 627 | 669 | - |
| 5 | g2379.t1 | PANTHER | PTHR10663:SF137 | BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1 | 5 | 1048 | 0.0 |
| 7 | g2379.t1 | PANTHER | PTHR10663 | GUANYL-NUCLEOTIDE EXCHANGE FACTOR | 5 | 1048 | 0.0 |
| 6 | g2379.t1 | PANTHER | PTHR10663:SF137 | BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1 | 1058 | 1789 | 0.0 |
| 8 | g2379.t1 | PANTHER | PTHR10663 | GUANYL-NUCLEOTIDE EXCHANGE FACTOR | 1058 | 1789 | 0.0 |
| 4 | g2379.t1 | Pfam | PF16213 | Dimerisation and cyclophilin-binding domain of Mon2 | 20 | 216 | 4.0E-38 |
| 3 | g2379.t1 | Pfam | PF12783 | Guanine nucleotide exchange factor in Golgi transport N-terminal | 398 | 555 | 4.1E-47 |
| 2 | g2379.t1 | Pfam | PF01369 | Sec7 domain | 677 | 861 | 1.1E-69 |
| 1 | g2379.t1 | Pfam | PF09324 | Domain of unknown function (DUF1981) | 1169 | 1250 | 9.1E-33 |
| 28 | g2379.t1 | ProSiteProfiles | PS50190 | SEC7 domain profile. | 670 | 859 | 44.529 |
| 17 | g2379.t1 | SMART | SM00222 | sec7_5 | 674 | 861 | 3.1E-93 |
| 10 | g2379.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 15 | 546 | 1.68E-6 |
| 9 | g2379.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 425 | 1482 | 3.34E-17 |
| 11 | g2379.t1 | SUPERFAMILY | SSF48425 | Sec7 domain | 668 | 863 | 3.53E-74 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0032012 | regulation of ARF protein signal transduction | BP |
| GO:0005085 | guanyl-nucleotide exchange factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K18442 (brefeldin A-inhibited guanine nucleotide-exchange protein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
