General information for g2404.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dynamin-like 120 kDa protein, mitochondrial.
Parent gene
- The parent gene g2404 is located on chr_3: 17684052..17685700 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2404 | g2404.t2 | isoform | g2404.t2 | 17682086 | 17685700 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon1 | 17682086 | 17682150 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS1 | 17682086 | 17682150 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon2 | 17682219 | 17682293 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS2 | 17682219 | 17682293 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon3 | 17682355 | 17682484 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS3 | 17682355 | 17682484 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon4 | 17682543 | 17682654 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS4 | 17682543 | 17682654 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon5 | 17682708 | 17684667 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS5 | 17682708 | 17684667 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon6 | 17684924 | 17685043 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS6 | 17684924 | 17685043 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon7 | 17685111 | 17685246 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS7 | 17685111 | 17685246 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon8 | 17685304 | 17685574 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS8 | 17685304 | 17685574 |
| chr_3 | g2404 | g2404.t2 | exon | g2404.t2.exon9 | 17685672 | 17685700 |
| chr_3 | g2404 | g2404.t2 | cds | g2404.t2.CDS9 | 17685672 | 17685700 |
| chr_3 | g2404 | g2404.t2 | TSS | g2404.t2 | NA | NA |
| chr_3 | g2404 | g2404.t2 | TTS | g2404.t2 | NA | NA |
Sequences
>g2404.t2 Gene=g2404 Length=2898
ATGTCTCAAATACTCCGTCGTAATTCAAGGATAAATTTTATTTATCGCTCGTTAAGACCG
GTTGTCATTAATGCCACAAAATTAAACTATTCAGTACTGAGTGGACGAAATCAATGGAAT
CATTATGGAAATTTGAGATATAGACAAAATCAATTATTTGATAACAACCTCTTGTTAAAA
AATAATCCAGCAAATTTCAGAAATTATGGAATGCTTGTTGGTAGAATATTGAGAGGTGCA
TTGAAACTGAGATATTTGTTACTTGGTGGTGCAGTTGGTGGAACAGTTACACTCAATAGT
AAATATGAGCAATGGAAAGAAGGTCTTCCTGATATGAAATGGCTTAATGAAGTCTTTCCT
GATAATGACCAATGGCAAAAGTTTTCAAATTCAGTTATCGGCATAACGGAGTCACTTAAA
AATTCTATTGAACTTGATCCAAAATTAAAGAAATTAGGTGAGGATAAATTGATTGAATGG
AGAAATTGGTTCGATAGTCGATTAGATAACGCCATTGAAGCAACTGAAATTGAAACACAG
CTAGAAAATGCCGAAAATCTCGGAGCAGATTTGGTACAGAAATCGAAAGTCATTGCAAAA
GAAATGAGTTATGAGGAACACAAAAGGAAAAATCAGATACTTCAAAAACAAATTGATCAG
CTGCAAACTGAAATCATGAATGTTCAAATCAAATATCAAAAAGAATTAGAAAAGCTTGAG
AAAGAAAATCGTGACCTTCGACAACAGTATTTGTTAACTAAAACAAATAGAAAGATGATA
TCTTCAAAGAAAATTAAAAAATCACTTATTGATATGTACTCTGAAGTGCTTGATGAATTA
AGCGGATATGATTCAAGTTACTCAACTGCAGACCATTTACCTCGTGTTGTTGTTGTTGGA
GATCAAAGTAGCGGAAAAACCTCTGTTCTCGAATCAATAGCACAAGCAAGAATATTTCCT
CGTGGAAGTGGTGAAATGATGACAAGAGCACCAGTAAAAGTGACACTCTCAGAAGGTCCA
TATCATGTCGCCGCTTTTCGTGATTCAAATCGAGAATTTGATTTGACTAAAGAAAGTGAT
TTAGCTGAACTCAGACGTGAAGTTGAAATTCGAATGAGAAATTCAGTTCGTGGTGGAAAA
ACTGTGAGCAATGAAGTCATTTCGATGACTGTTAAAGGACCAGGTTTGCAACGAATGGTT
CTTGTTGATTTACCAGGAATAATATCAACCCAGACAGTTGATATGGCAGCTGACACTAAA
GATTCAATTACCATGATGACAAAACATTATATGAGCAATCCAAATGCTATCATTTTGTGT
ATTCAAGATGGTTCAGTTGATGCAGAACGTTCTGCAGTGACAGATTTAGTGGCCAATTGT
GATCCACTTGGCAAAAGAACAATATTTGTTATGACTAAAGTCGATATGGCTGAAAGTCTG
GCTGACCCAGATAGAATTCGTCGTATTTTAAGTGGAAAGCTTTTTCCTATGAAGGCATTG
GGATATTTCGCAGTTGTGACAGGACGTGGAAGAAAAGATGACTCGATTGATACTATTCGA
GACTATGAAGAAAATTTCTTTAAAAATTCAAAACTGTTTCAAAGCGGCGTTACAATGTCA
CATCAATGCACATCGAGAAACTTAAGTCTTGCAGTTGCTGATCGATTTTGGAAAATGGTG
CGTGAAACGATAGAACAACAAGCTGACGCTTTTAAAGCTACTCGATTTAACCTTGAAACA
GAATGGAAAAACAACTTTCCTAGAATTCGTGAGTCAGGCCGTGATGAATTGTATGAAAAG
GCGAGAGGTGAAGTGCTTGATGAGGTTGTAAATTTATCACAAATAAGTTCAAAGAAGTGG
GAAGAGCTTTTAAATAAGAAGCTTTGGGAAAAGATTTCAAATTATGTTTTCGAAAATATT
TACCTACCTGCAGCACAATCTGGTTCACAAAATTCATTCAATACGATGGTTGATATAAAA
TTGCGTCAATGGGCTGAAGAAGTTTTACCTTCAAAAAGCGTCGAGACGGGTTGGGAAACT
TTGCAAGATGAATTTGCAAATTTAATTGAAAAGGCTAAAAAGAATCCTGATCATGATGAT
ATTTTTGATCATTTGAAATCAGCTGTCATTGATGAAGCAATGAGACGACATTCCTGGGAA
GATAAAGCTATGGACATGCTTCGTGTCATTCAATTAAATACACTCGAAGATCGTAATGTT
CATGACAAACAAGAATGGGATCAAGCTGTGAAATTTCTTGAAAGCTCAGTTAAAGATAAA
CTTTTGCATACTGAACAAACAATTGCAGAAATGTTCGGACCAACAACAACACAAAAATGG
CTACATTGGAGGTCACCAACAGAAGATCAAAGAAAACGTAGACATGTCAAAGATGAACTC
GATAAAATTCTTAATAGTGATAAGAAACATCCGCCAACATTGAGTTATGATGAATTGACA
ACAGTACGCAAGAATTTACAAAGAAGTAATATTGAAGTCGAAACTGATTATATTAGAGAA
ACTTGGTATCCAATTTATCGAAAACACTTCCTCAATCATGCATTATCAAGGGCTTATGAT
CTTAGAAAAGCTTACTACTTGTATACACAACAAAATGAAAACTTTGAGATAAACTGCAGC
GATGTCGTGCTGTTTTGGAGAATTCAGCAAGTGATTAAAGTGACTGCAAATGCTTTACGT
CAACAAATAATAAATCGAGAAGCAAGAAGAGTTGACAAGGAAATTAAAGAAGTTTTAGAT
GAATTTGCTGATGATGAAGATAAGAAGGTGCAATTGCTCACGGGTAAACGTGTAACATTA
GCAGAAGAATTAATTCGCGTGCGACACATTCAAGAAAAGTTGGAAGAATTCATTAATGCA
TTGAACACAGAAAAATAA
>g2404.t2 Gene=g2404 Length=965
MSQILRRNSRINFIYRSLRPVVINATKLNYSVLSGRNQWNHYGNLRYRQNQLFDNNLLLK
NNPANFRNYGMLVGRILRGALKLRYLLLGGAVGGTVTLNSKYEQWKEGLPDMKWLNEVFP
DNDQWQKFSNSVIGITESLKNSIELDPKLKKLGEDKLIEWRNWFDSRLDNAIEATEIETQ
LENAENLGADLVQKSKVIAKEMSYEEHKRKNQILQKQIDQLQTEIMNVQIKYQKELEKLE
KENRDLRQQYLLTKTNRKMISSKKIKKSLIDMYSEVLDELSGYDSSYSTADHLPRVVVVG
DQSSGKTSVLESIAQARIFPRGSGEMMTRAPVKVTLSEGPYHVAAFRDSNREFDLTKESD
LAELRREVEIRMRNSVRGGKTVSNEVISMTVKGPGLQRMVLVDLPGIISTQTVDMAADTK
DSITMMTKHYMSNPNAIILCIQDGSVDAERSAVTDLVANCDPLGKRTIFVMTKVDMAESL
ADPDRIRRILSGKLFPMKALGYFAVVTGRGRKDDSIDTIRDYEENFFKNSKLFQSGVTMS
HQCTSRNLSLAVADRFWKMVRETIEQQADAFKATRFNLETEWKNNFPRIRESGRDELYEK
ARGEVLDEVVNLSQISSKKWEELLNKKLWEKISNYVFENIYLPAAQSGSQNSFNTMVDIK
LRQWAEEVLPSKSVETGWETLQDEFANLIEKAKKNPDHDDIFDHLKSAVIDEAMRRHSWE
DKAMDMLRVIQLNTLEDRNVHDKQEWDQAVKFLESSVKDKLLHTEQTIAEMFGPTTTQKW
LHWRSPTEDQRKRRHVKDELDKILNSDKKHPPTLSYDELTTVRKNLQRSNIEVETDYIRE
TWYPIYRKHFLNHALSRAYDLRKAYYLYTQQNENFEINCSDVVLFWRIQQVIKVTANALR
QQIINREARRVDKEIKEVLDEFADDEDKKVQLLTGKRVTLAEELIRVRHIQEKLEEFINA
LNTEK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g2404.t2 | CDD | cd08771 | DLP_1 | 292 | 565 | 2.01757E-87 |
| 10 | g2404.t2 | Coils | Coil | Coil | 174 | 194 | - |
| 11 | g2404.t2 | Coils | Coil | Coil | 204 | 256 | - |
| 9 | g2404.t2 | Gene3D | G3DSA:3.40.50.300 | - | 266 | 573 | 5.2E-77 |
| 2 | g2404.t2 | PANTHER | PTHR11566 | DYNAMIN | 217 | 965 | 0.0 |
| 3 | g2404.t2 | PANTHER | PTHR11566:SF67 | DYNAMIN-LIKE 120 KDA PROTEIN, MITOCHONDRIAL | 217 | 965 | 0.0 |
| 5 | g2404.t2 | PRINTS | PR00195 | Dynamin signature | 293 | 311 | 2.8E-18 |
| 4 | g2404.t2 | PRINTS | PR00195 | Dynamin signature | 318 | 335 | 2.8E-18 |
| 6 | g2404.t2 | PRINTS | PR00195 | Dynamin signature | 393 | 410 | 2.8E-18 |
| 7 | g2404.t2 | PRINTS | PR00195 | Dynamin signature | 462 | 478 | 2.8E-18 |
| 1 | g2404.t2 | Pfam | PF00350 | Dynamin family | 296 | 474 | 2.8E-40 |
| 14 | g2404.t2 | ProSiteProfiles | PS51718 | Dynamin-type guanine nucleotide-binding (G) domain profile. | 290 | 565 | 62.082 |
| 13 | g2404.t2 | SMART | SM00053 | dynamin_3 | 270 | 519 | 3.5E-12 |
| 8 | g2404.t2 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 269 | 565 | 6.91E-49 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005739 | mitochondrion | CC |
| GO:0005525 | GTP binding | MF |
| GO:0007005 | mitochondrion organization | BP |
| GO:0006915 | apoptotic process | BP |
| GO:0003924 | GTPase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K17079 (optic atrophy protein 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
