General information for g2446.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as RNA cytidine acetyltransferase.
Parent gene
- The parent gene g2446 is located on chr_3: 18016328..18017723 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2446 | g2446.t3 | TTS | g2446.t3 | 18014441 | 18014441 |
| chr_3 | g2446 | g2446.t3 | isoform | g2446.t3 | 18014506 | 18016328 |
| chr_3 | g2446 | g2446.t3 | exon | g2446.t3.exon1 | 18014506 | 18016328 |
| chr_3 | g2446 | g2446.t3 | cds | g2446.t3.CDS1 | 18014506 | 18016110 |
| chr_3 | g2446 | g2446.t3 | TSS | g2446.t3 | NA | NA |
Sequences
>g2446.t3 Gene=g2446 Length=1823
TGGCATCAACAATAAATGGATATGAAGGAACTGGAAGATCACTAAGTTTGAAATTATTGT
CACAAATTCAGAAGGAAAACAATGCACCGCCTCCTATCAAATTAGAAGAATCAATTCGTT
ATAATCCAAATGATAGTGTTGAAAAATGGTTAACAACATTGCTTTGTTTGGATGCACAAG
TTGTTCCTGCGCTTAATTCGGGTTGTCCAACGCCAGACATGTGTGAACTTTATTATATCG
ACAGAGATGCTCTCTTCTCTTATCATCGAGCTGCAGAAGCATTTTTACAACGAGTTGTTG
CAATATTTGTTTCATCGCATTACAAAAATACACCAAATGATTTACAAATGCTTAGTGATG
CACCGGCACATCATTTGTTTTGCCTACTTGGTCCAATCACGAAAAAAGATCAATTGCCTG
AAATTCTTGTAATCATTCAAGTTTGTCTTGAAGGAAAAATCTCACAAAGACGCTTAAATG
ATGCAACTGGATCGAAAGCAGCTGGTGATTTGATTCCTTGGAATGTATCTGAACAATTCA
ATGATAGAGAGTTTACTAAATTAGCAGGTGCAAGAATTGTTCGCATTGCAACTCATCCAA
ATTATCAAAGAATGGGCTATGGTAAAAAAGCATTGAAATTGCTCAAGAATTACTATGAAG
GTAAATTTACATCTCTGAATGAAACTACAGCAAATGATGAAGAAAATGATGGAATTGAAG
AAATTAATGACGAAGATGCTGATATATTGACAGAAGTTATCAAACCAAGAAAAAAAATTC
CAACTCTTTTGAAACGTTTACAAGAGAGAAAACCGGAAATGCTTGATTATATTGGAACAT
CTTATGGAATGACTCAAGAACTTTTAAAATTCTGGAAAAGTCAAAAGTTTATTCCAGTTT
ATTTAAGTCAAAAAGAAAATGACTTGACTGGCGAAAATTCTTGTATCATGATATCTTCAT
TAAATGATGAGCGAGTTAAAACAAAAAATTGGCTTCAAGAATATTATATTGATTTTCGTC
GTAGACTTTTGAGACTGTTGCCAAAAGCTTTTCGCAAATATACAACTGGATTAGGACTCT
CACTTCTAGATAACAAAAGCGTGGTTGTCCCAATTAAAGAACTCGATCAACTTGAATTAA
ATTCATTTTTCACACCACATGATGTGCAACGACTTGAGTCGTATGTTCGCAATCAAATTG
AGTATAGATTGATATTAGATTTAACTTCTGATTTATCATCGTTATACTTTCAAATGAGAC
TGCCTAACACACCGCTTGATGCTCTGCAAAAAGCAATATTGCTTGGAATAGGCACTCAAA
ATAAAAACTTGGATGATCTTCAAAATGAATTTAATATGCCAAGTAGTCAGATTCTTGCTA
AATTTTCTGACACAATAAGGAAACTTACTAAAAATCTTTTGCAAATTATGGAGAAAACAA
TTGAAAGTGAGATGCTTGATGAAGGACAATTGAACGAAGGAAAAGAATTTAAACCATTAG
AGCAAACAATTGAAGAAGAACTCGATGAAGAAGCTAAAAAACTTGAGAAAAAGCAGAAAA
AAGAATTGATTAAATTGAAGAAGGAATCATTAGCTCAGTATGCTATTAAAGGGACAAATG
AAGATTGGTCAAAAGCATTAAAAAGTGGCAACAACAAATCAATTATTTCTGTTAAAAGTG
GAGAAAAACGTAGTTTTGAAAACGAAGATGATGAAATAGCCTCAAATGAGCAAAAAGAAA
AAGAAGGTTGGAATAAAAATAAAAAGAAGAAATTCCAATACAATCAAACTAATAAGAAGA
AAGACAAATTTTTTAAAAAATGA
>g2446.t3 Gene=g2446 Length=534
MCELYYIDRDALFSYHRAAEAFLQRVVAIFVSSHYKNTPNDLQMLSDAPAHHLFCLLGPI
TKKDQLPEILVIIQVCLEGKISQRRLNDATGSKAAGDLIPWNVSEQFNDREFTKLAGARI
VRIATHPNYQRMGYGKKALKLLKNYYEGKFTSLNETTANDEENDGIEEINDEDADILTEV
IKPRKKIPTLLKRLQERKPEMLDYIGTSYGMTQELLKFWKSQKFIPVYLSQKENDLTGEN
SCIMISSLNDERVKTKNWLQEYYIDFRRRLLRLLPKAFRKYTTGLGLSLLDNKSVVVPIK
ELDQLELNSFFTPHDVQRLESYVRNQIEYRLILDLTSDLSSLYFQMRLPNTPLDALQKAI
LLGIGTQNKNLDDLQNEFNMPSSQILAKFSDTIRKLTKNLLQIMEKTIESEMLDEGQLNE
GKEFKPLEQTIEEELDEEAKKLEKKQKKELIKLKKESLAQYAIKGTNEDWSKALKSGNNK
SIISVKSGEKRSFENEDDEIASNEQKEKEGWNKNKKKKFQYNQTNKKKDKFFKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g2446.t3 | CDD | cd04301 | NAT_SF | 118 | 145 | 5.15441E-4 |
| 11 | g2446.t3 | Coils | Coil | Coil | 428 | 452 | - |
| 10 | g2446.t3 | Gene3D | G3DSA:3.40.630.30 | - | 8 | 157 | 1.8E-41 |
| 9 | g2446.t3 | Gene3D | G3DSA:3.40.630.30 | - | 185 | 246 | 5.8E-12 |
| 6 | g2446.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 487 | 516 | - |
| 7 | g2446.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 487 | 534 | - |
| 8 | g2446.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 519 | 534 | - |
| 3 | g2446.t3 | PANTHER | PTHR10925:SF5 | RNA CYTIDINE ACETYLTRANSFERASE | 2 | 513 | 1.0E-168 |
| 4 | g2446.t3 | PANTHER | PTHR10925 | N-ACETYLTRANSFERASE 10 | 2 | 513 | 1.0E-168 |
| 2 | g2446.t3 | Pfam | PF13718 | GNAT acetyltransferase 2 | 25 | 249 | 3.4E-93 |
| 1 | g2446.t3 | Pfam | PF13725 | Possible tRNA binding domain | 258 | 473 | 6.1E-63 |
| 5 | g2446.t3 | SUPERFAMILY | SSF55729 | Acyl-CoA N-acyltransferases (Nat) | 115 | 149 | 8.21E-6 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008080 | N-acetyltransferase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
