General information for g2524.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-binding cassette sub-family G member 4.
Parent gene
- The parent gene g2524 is located on chr_3: 18432333..18434308 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2524 | g2524.t1 | TTS | g2524.t1 | 18429759 | 18429759 |
| chr_3 | g2524 | g2524.t1 | isoform | g2524.t1 | 18429784 | 18434308 |
| chr_3 | g2524 | g2524.t1 | exon | g2524.t1.exon1 | 18429784 | 18430128 |
| chr_3 | g2524 | g2524.t1 | cds | g2524.t1.CDS1 | 18429784 | 18430128 |
| chr_3 | g2524 | g2524.t1 | exon | g2524.t1.exon2 | 18430183 | 18430439 |
| chr_3 | g2524 | g2524.t1 | cds | g2524.t1.CDS2 | 18430183 | 18430439 |
| chr_3 | g2524 | g2524.t1 | exon | g2524.t1.exon3 | 18430497 | 18431622 |
| chr_3 | g2524 | g2524.t1 | cds | g2524.t1.CDS3 | 18430497 | 18431622 |
| chr_3 | g2524 | g2524.t1 | exon | g2524.t1.exon4 | 18432699 | 18432949 |
| chr_3 | g2524 | g2524.t1 | cds | g2524.t1.CDS4 | 18432699 | 18432949 |
| chr_3 | g2524 | g2524.t1 | exon | g2524.t1.exon5 | 18433012 | 18433765 |
| chr_3 | g2524 | g2524.t1 | cds | g2524.t1.CDS5 | 18433012 | 18433765 |
| chr_3 | g2524 | g2524.t1 | exon | g2524.t1.exon6 | 18433858 | 18434159 |
| chr_3 | g2524 | g2524.t1 | cds | g2524.t1.CDS6 | 18433858 | 18434159 |
| chr_3 | g2524 | g2524.t1 | exon | g2524.t1.exon7 | 18434242 | 18434308 |
| chr_3 | g2524 | g2524.t1 | cds | g2524.t1.CDS7 | 18434242 | 18434308 |
| chr_3 | g2524 | g2524.t1 | TSS | g2524.t1 | 18434369 | 18434369 |
Sequences
>g2524.t1 Gene=g2524 Length=3102
ATGAGTAGGTGGGATATAAGTTTCAAGAATATAGAATACAGTATATTTGGTTCTTTAATT
CATAAAAATAAAAAAATCTTGAATGACATAAGTGGTGAATTTCGTTCAAATGAGTTGACT
GCAATAATTGGTTCTAGTGGCAGTGGAAAAAGCTCTCTATTAAACATTCTATCGGGTTAT
CAAAGAAAAAACGTCAAAGGATCAATCGAGCTTAATGGAATTCAAAGTTCACAACTCATT
CAAGAATTTTCGTCATACGTAATGCAAGAGTATACATTTCATAAATACATCACAGTTCGA
GAGACATTATTATTCCGAATCAATTGTAAAATTTCTAAACAACAAGATGAGAGCATAAAG
AATGAGAAGATCGAGATGATTTTAAATAAAATTGGCCTTATTGATAAAGAGCATGTTTAT
TGTGAAAAATTGAGTGGTGGTGAAATTAAGCGATTGTCAATTGCTGTTGAACTTTTAGAT
GATCCTAAAATTTTATTTATTGACGAATGCACAACGGGCTTAGATAGTGTGACTTCTACA
CAATGCATTCAACTTCTTAAGAATATCTCTAAAGAAGGACGTACGATAATTACTTCAATT
CATCAACCAAGTGCTTTAATATTCAATATGTTTGATCATATTTACGCGCTTGCAAACGGT
CAATGCATTTACCAAGGTTCAACGGAAAGTTTAGTTCCTTTTCTATCTGAGCTTGATCTT
ATTTGTCCACACAACTATAATATAACTGATTTTTTAATGGAGATTGCAAACAATGATTAT
GGACCTCAAAATAATCGATTAATAAATAAAGTTGAGATAAGATCACATCGTCATGGAGTG
TGTAAAAATAATGACTCATCACCAATAATAATTAGCGCGTTAGAAGTTCAAAGTTTGAGA
AATGAAATTTCACAATTATTGAAAAGAAACATGCTCAACAATTATCGTGATAAGACATTC
ACAATTATGAGAATTTTAATTCACCTAATCATAGCAGGAATTATTGGAATAATTTATAAA
GGAATTGGCAAAGATGGAAGTCAAATACTCAATGTATACAAATTTTTATTTTTTAATATA
TTCATCTTAATGTTTACTGCTTTTAGCTCTCTTCAAACTTCATTTCCCACTGAATATTCA
ATTGTAAAGCGCGAAAATTTCAACAAGATGTACACGGTGTTTAGTTACTTCATAGCTCAG
AATTTAGCTGATATACCTATTATATTTATATCAAATTTATTATACGTTATAATTTCATAC
GTGATGACAGATCAACCATTTGAGATTTTTAGATTAATTTATTACTTTTTCATTATACTC
TTGATGAGTTTTGCTGCTCAAGGTCTTGGATTGGTTGCTGGGTCATTTTTAAATGAAAAA
AAGGAAATTTTAAAAAATATCTCTGGAGAATTTAACGGAGGTCATATAAATACAATCTTG
GGTTTAAGCGGTAGCGGCAAAACAAGTCTTTTAAATGTTCTCTCAGGGTTTAAAAAAACA
AATGTAAGCGGAAAGATAATGATAAATGGTAGAGAAATCCCAGTTGATAAAATTAGAAAA
ATTTCGTCATACGTAATGCAAGATCAGAGTCTTCATTCACATCTTACTACATGCGAAATT
GTGACACTCTCACTAAATTTAAGAGATAAAAATCAGCTGAGTGCCTCTGAAAGGAAAAAC
AAAATTGAAAATTTGCTTTTAAAACTTAACATAGAAAATAAAAGAAATTCATTGATAAAA
GACCTGAGTGGAGGTGAAATTAAACGACTTTCGATTGCAATTGAATTGGTAAACGATCCG
AAAATTTTATTTCTCGATGAGCCAACTACAAATCTTGATAGTGTTTCATCAACACATTGC
ATTGAATTACTTAAAAAATTAGCAATTGATGAGAGAAAAATTATTGTGTGCACTATTCAT
CAACCTTCTACACTATTATTAAAAATGTTTGATCAAATTTATGCATTAGCTGATGGTCAA
TGTATTTTTCAAGGTTCATCATTATCAAACATAGTTCAATTTTTAAAAGAACTCGAATTG
CCATGTCCAAGTACTTATAATCCCACAGACTTTTTAATGGAAATAGCAAATAATGATTAT
GGACCTCAAAATCATAGATTAGTAAAAAAGATTAAAAATGGCAGGAATATAAACTACAAA
AACACTGAGTTGTTGAACAATAACAACAAAATAATTTATCCAGAAAATAATTATCGTAAT
GAATATTTAGAAGTTCAACAATCATCGTTAATTAAAAACTATCATTGCTCATACATTCAT
CAAGTATACTATCTTTTAACAAGAACTTATATGATGATTTCACGTGATTCAACGCTCCTG
AATATGCGTCTTTTCATTCATCTTGTCCTTGGATTGGTCTTTGGATTCATATATAGAGAC
GTTGGCAACAAAGGATCAGCAATGTTAGATAATTATCGATATTTGGTTGTTTCTGTGGTA
TTTCTTTTGTACACTTCTTACTATTCGTTATTTGTTACTTTTCCACTCGAATTTGCAACA
ATAAAACGTGAACATTTTAATAATTGGTATTCGACACGAGCTTATTACACTGCTTTCATT
CTATCTGATGTACCAATTACTATAGCATGCTGCATTATTTATGTAACAATAACTTATTGG
TTAACAGATCAACCACGTGAGCTTTATCGATTTCTAATATTCTTGAGTTTTACAATTTTA
ATGTCATTTGCTGCTCAATCACTCTCTGTCATGTTTACAGCATTGATGGACTTAAAGTCC
GCAACGATTTTTGGAAGTATGCTTCTATCACCATTTTTTCTATTCTCTGGTATAATGATA
TTGAGCAAAGATGCACCTGAAATATTTTCCTTTTTCTTCAATACAAATTTTCTTGATAGC
AGTTTAAAAGGAGTTTTGAATTCAGTACTTGGATTTAATAGAACAAAATTGCCGTGCGAT
GAAATTTTTTGTTTCCTAGAAAATCCTAAAAAAATGTTGAGAGATTTTGGAGCTAATATT
GATATTACTAAAGCTTATTATATTTTGATAATTTACATTTTAATATCACAAATTTTAGCA
TTTACCTTTATAAATTATAGACTTAAATATAAACAAACTTGA
>g2524.t1 Gene=g2524 Length=1033
MSRWDISFKNIEYSIFGSLIHKNKKILNDISGEFRSNELTAIIGSSGSGKSSLLNILSGY
QRKNVKGSIELNGIQSSQLIQEFSSYVMQEYTFHKYITVRETLLFRINCKISKQQDESIK
NEKIEMILNKIGLIDKEHVYCEKLSGGEIKRLSIAVELLDDPKILFIDECTTGLDSVTST
QCIQLLKNISKEGRTIITSIHQPSALIFNMFDHIYALANGQCIYQGSTESLVPFLSELDL
ICPHNYNITDFLMEIANNDYGPQNNRLINKVEIRSHRHGVCKNNDSSPIIISALEVQSLR
NEISQLLKRNMLNNYRDKTFTIMRILIHLIIAGIIGIIYKGIGKDGSQILNVYKFLFFNI
FILMFTAFSSLQTSFPTEYSIVKRENFNKMYTVFSYFIAQNLADIPIIFISNLLYVIISY
VMTDQPFEIFRLIYYFFIILLMSFAAQGLGLVAGSFLNEKKEILKNISGEFNGGHINTIL
GLSGSGKTSLLNVLSGFKKTNVSGKIMINGREIPVDKIRKISSYVMQDQSLHSHLTTCEI
VTLSLNLRDKNQLSASERKNKIENLLLKLNIENKRNSLIKDLSGGEIKRLSIAIELVNDP
KILFLDEPTTNLDSVSSTHCIELLKKLAIDERKIIVCTIHQPSTLLLKMFDQIYALADGQ
CIFQGSSLSNIVQFLKELELPCPSTYNPTDFLMEIANNDYGPQNHRLVKKIKNGRNINYK
NTELLNNNNKIIYPENNYRNEYLEVQQSSLIKNYHCSYIHQVYYLLTRTYMMISRDSTLL
NMRLFIHLVLGLVFGFIYRDVGNKGSAMLDNYRYLVVSVVFLLYTSYYSLFVTFPLEFAT
IKREHFNNWYSTRAYYTAFILSDVPITIACCIIYVTITYWLTDQPRELYRFLIFLSFTIL
MSFAAQSLSVMFTALMDLKSATIFGSMLLSPFFLFSGIMILSKDAPEIFSFFFNTNFLDS
SLKGVLNSVLGFNRTKLPCDEIFCFLENPKKMLRDFGANIDITKAYYILIIYILISQILA
FTFINYRLKYKQT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g2524.t1 | Gene3D | G3DSA:3.40.50.300 | - | 6 | 237 | 1.0E-52 |
| 14 | g2524.t1 | Gene3D | G3DSA:3.40.50.300 | - | 453 | 678 | 4.8E-50 |
| 8 | g2524.t1 | PANTHER | PTHR48041:SF78 | ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A-RELATED | 4 | 459 | 0.0 |
| 10 | g2524.t1 | PANTHER | PTHR48041 | ABC TRANSPORTER G FAMILY MEMBER 28 | 4 | 459 | 0.0 |
| 7 | g2524.t1 | PANTHER | PTHR48041:SF78 | ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A-RELATED | 459 | 1026 | 0.0 |
| 9 | g2524.t1 | PANTHER | PTHR48041 | ABC TRANSPORTER G FAMILY MEMBER 28 | 459 | 1026 | 0.0 |
| 5 | g2524.t1 | Pfam | PF00005 | ABC transporter | 27 | 171 | 1.1E-23 |
| 2 | g2524.t1 | Pfam | PF19055 | ABC-2 type transporter | 201 | 264 | 7.9E-6 |
| 4 | g2524.t1 | Pfam | PF01061 | ABC-2 type transporter | 303 | 457 | 5.2E-28 |
| 6 | g2524.t1 | Pfam | PF00005 | ABC transporter | 464 | 609 | 2.7E-24 |
| 1 | g2524.t1 | Pfam | PF19055 | ABC-2 type transporter | 640 | 698 | 2.3E-5 |
| 3 | g2524.t1 | Pfam | PF01061 | ABC-2 type transporter | 761 | 967 | 1.5E-31 |
| 20 | g2524.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 318 | - |
| 30 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 319 | 339 | - |
| 21 | g2524.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 340 | 350 | - |
| 35 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 351 | 372 | - |
| 19 | g2524.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 373 | 392 | - |
| 32 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 393 | 421 | - |
| 25 | g2524.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 422 | 432 | - |
| 34 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 433 | 457 | - |
| 17 | g2524.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 458 | 779 | - |
| 33 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 780 | 799 | - |
| 24 | g2524.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 800 | 810 | - |
| 28 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 811 | 834 | - |
| 18 | g2524.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 835 | 854 | - |
| 27 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 855 | 882 | - |
| 23 | g2524.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 883 | 887 | - |
| 29 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 888 | 914 | - |
| 15 | g2524.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 915 | 920 | - |
| 26 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 921 | 941 | - |
| 22 | g2524.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 942 | 1004 | - |
| 31 | g2524.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1005 | 1026 | - |
| 16 | g2524.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1027 | 1033 | - |
| 47 | g2524.t1 | ProSitePatterns | PS00211 | ABC transporters family signature. | 144 | 158 | - |
| 48 | g2524.t1 | ProSitePatterns | PS00211 | ABC transporters family signature. | 582 | 596 | - |
| 52 | g2524.t1 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 6 | 244 | 17.867 |
| 51 | g2524.t1 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 449 | 683 | 17.114 |
| 49 | g2524.t1 | SMART | SM00382 | AAA_5 | 36 | 221 | 1.8E-9 |
| 50 | g2524.t1 | SMART | SM00382 | AAA_5 | 473 | 659 | 4.4E-7 |
| 11 | g2524.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 6 | 242 | 1.17E-45 |
| 12 | g2524.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 458 | 666 | 1.06E-43 |
| 45 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 320 | 342 | - |
| 43 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 355 | 377 | - |
| 39 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 397 | 419 | - |
| 40 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 432 | 454 | - |
| 46 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 474 | 496 | - |
| 37 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 779 | 801 | - |
| 42 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 816 | 838 | - |
| 41 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 859 | 881 | - |
| 36 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 891 | 913 | - |
| 38 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 920 | 942 | - |
| 44 | g2524.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1006 | 1028 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005524 | ATP binding | MF |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | MF |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
