General information for g2640.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Glucose-6-phosphate 1-dehydrogenase.
Parent gene
- The parent gene g2640 is located on chr_3: 19248964..19249820 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2640 | g2640.t3 | isoform | g2640.t3 | 19246648 | 19249820 |
| chr_3 | g2640 | g2640.t3 | exon | g2640.t3.exon1 | 19246648 | 19246978 |
| chr_3 | g2640 | g2640.t3 | cds | g2640.t3.CDS1 | 19246649 | 19246978 |
| chr_3 | g2640 | g2640.t3 | exon | g2640.t3.exon2 | 19247040 | 19247224 |
| chr_3 | g2640 | g2640.t3 | cds | g2640.t3.CDS2 | 19247040 | 19247156 |
| chr_3 | g2640 | g2640.t3 | exon | g2640.t3.exon3 | 19248949 | 19249820 |
| chr_3 | g2640 | g2640.t3 | TSS | g2640.t3 | 19249823 | 19249823 |
| chr_3 | g2640 | g2640.t3 | TTS | g2640.t3 | NA | NA |
Sequences
>g2640.t3 Gene=g2640 Length=1388
TTTGTTTACCTCTCTCTGACTGTGTTTTAAAATTTTTTGTTTTTCTTATTTTTCACCTTA
AAACTGATTAATTCATCAATAAACTGTTCGAGGTCGATAGATGTGATAAGAGAAAAGTGA
AAAGAAGCGATCGTCTGATTTTATAATAATTATTTATATAAATTTTTATTGAAATTTCAT
TGCCGCTTTTTATTAACATTCTCTTTCAATGTGTTGAGTGTTGAAGTTAAAATTAAATAA
TTAATTTGATATGCAAATAAGCTTATAAAAAGAACATTGAACTTTCAAGAATTTTGACTA
CACAAAGACAATTGTGTGACGTTAAAAGAATTTTTGTTTCTTGGAATACAAATGCAAAAG
TACTGAGTTTCATTTGACCTGTTGATTCTTTTACGCTATTTGTGATTTCATCGGCTTGTG
ACGTAGATATCGTTCTTTTATACGTACACATTTTTTCAACTCTTTACTGTAAAATATTAG
AGAGAGCAAAAGAGAGAGAAAAAACATTGATGGTCAATAAAAACGAAAGAAAAAGTCTAC
GAGTGTGCTGTGTTGTGTTATTTGAGCTTGCCAAGTGATTAGACGTACATTAGTTATTAC
TCTGTAAATTTAATATTCGCGGAAAAAGGAAAAAAAATAGAGATTAAAAATTGCATCTCA
TGTGATTTTGTCGACTCGAACTTGAAGAGAACTTACACAAATTTTCAGTTGACAATTGCT
TCTCGTGAAGGAAAGTTGAACGACACCTATAGCTTTATATATATTTATCTACAAGCTAGT
CTGCCTGCTTATCTAAACAGTTTTTGAAACAAATATATTTTTTGTGTAGACAGCAAAGAC
AACGGTAACCGACAAGATGATGCAAAATAACGTATCTCAAAAAATCAATCTACTAAATCA
ACTTACGAGGCAGAATAGCAACGGCAGTAATAACGGCAATATGAATAATCAAAAAACTCT
CGATATTATCCGTGAGGATCTTGGTCATCTAGTTGAAACGGAAGGCACATACTGGGACAG
TCGACATCCGCATATTTTTGTTGTTATGGGTGCTTCGGGAGATTTGGCAAAGAAGAAAAT
TTATCCAACACTCTGGTGGCTTTATCGTGACAATTTATTGCCGCCTGCGACAATTTTCAT
TGGTTACGCCCGTAGCAAACTTTCCATCGAAGAGTTACGCAGCAAGTGTGATCAGTACAT
GAAGGTGAAAGATGATGAAAAGGAAAAATACGAGCAATTTTGGAAGATTAATTACTACGT
TGTTGGCTCTTATACTGAGCGTCGTGATTTTGAAATGTTGAATCAAGAAATGTCGAAGCA
TGATAATCTATCGACTGCTAATCGTCTCTTCTATCTCGCCCTACCGCCGTCTGTATTTGA
ATCTGTTA
>g2640.t3 Gene=g2640 Length=149
MNNQKTLDIIREDLGHLVETEGTYWDSRHPHIFVVMGASGDLAKKKIYPTLWWLYRDNLL
PPATIFIGYARSKLSIEELRSKCDQYMKVKDDEKEKYEQFWKINYYVVGSYTERRDFEML
NQEMSKHDNLSTANRLFYLALPPSVFESV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g2640.t3 | Coils | Coil | Coil | 76 | 96 | - |
| 5 | g2640.t3 | Gene3D | G3DSA:3.40.50.720 | - | 27 | 149 | 5.9E-38 |
| 2 | g2640.t3 | PANTHER | PTHR23429:SF0 | GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE | 30 | 149 | 4.9E-37 |
| 3 | g2640.t3 | PANTHER | PTHR23429 | GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD | 30 | 149 | 4.9E-37 |
| 1 | g2640.t3 | Pfam | PF00479 | Glucose-6-phosphate dehydrogenase, NAD binding domain | 34 | 149 | 3.5E-31 |
| 4 | g2640.t3 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 28 | 149 | 1.22E-50 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0050661 | NADP binding | MF |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | MF |
| GO:0006006 | glucose metabolic process | BP |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
