Gene loci information

Transcript annotation

  • This transcript has been annotated as Calcium/calmodulin-dependent protein kinase type II alpha chain.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2642 g2642.t1 TTS g2642.t1 19274177 19274177
chr_3 g2642 g2642.t1 isoform g2642.t1 19274327 19275072
chr_3 g2642 g2642.t1 exon g2642.t1.exon1 19274327 19274361
chr_3 g2642 g2642.t1 cds g2642.t1.CDS1 19274327 19274361
chr_3 g2642 g2642.t1 exon g2642.t1.exon2 19274435 19274547
chr_3 g2642 g2642.t1 cds g2642.t1.CDS2 19274435 19274547
chr_3 g2642 g2642.t1 exon g2642.t1.exon3 19274672 19274786
chr_3 g2642 g2642.t1 cds g2642.t1.CDS3 19274672 19274786
chr_3 g2642 g2642.t1 exon g2642.t1.exon4 19274866 19274960
chr_3 g2642 g2642.t1 cds g2642.t1.CDS4 19274866 19274960
chr_3 g2642 g2642.t1 exon g2642.t1.exon5 19275020 19275072
chr_3 g2642 g2642.t1 cds g2642.t1.CDS5 19275020 19275072
chr_3 g2642 g2642.t1 TSS g2642.t1 NA NA

Sequences

>g2642.t1 Gene=g2642 Length=411
ATGACTGAACAATTGATTGAAGCCATAAATAATGGTGATTTTGATGCATATACCAAAATA
TGTGATCCTCATGTAACTGCATTCGAGCCAGAATCGCTTGGTAATTTAGTAGAGGGAATG
GACTTTCATAAATTCTATTTTGAGAATGTGCTAGGAAAGAATTGCAAGGCTATTAATACA
ACCATTCTAAATCCTCATGTTCATCTATTGGGCGATGAAACTGCATGTATTGCATATGTT
CGACTAACTCAATACATTGATAAACAAGGTCACGCTCACACTCATCAATCGGAAGAGACT
CGTGTTTGGCACAAGCGTGATGGAAAATGGCAGAACGTTCACATTCATCGTAGCTATACA
GGCAATTTGAGTGGAGCAACACCATTTGATTTTGGTCACGGTAGTAAATGA

>g2642.t1 Gene=g2642 Length=136
MTEQLIEAINNGDFDAYTKICDPHVTAFEPESLGNLVEGMDFHKFYFENVLGKNCKAINT
TILNPHVHLLGDETACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDGKWQNVHIHRSYT
GNLSGATPFDFGHGSK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g2642.t1 Gene3D G3DSA:3.10.450.50 - 1 123 0
2 g2642.t1 PANTHER PTHR24347 SERINE/THREONINE-PROTEIN KINASE 1 101 0
3 g2642.t1 PANTHER PTHR24347:SF398 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT GAMMA 1 101 0
1 g2642.t1 Pfam PF08332 Calcium/calmodulin dependent protein kinase II association domain 1 119 0
4 g2642.t1 SUPERFAMILY SSF54427 NTF2-like 2 118 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004683 calmodulin-dependent protein kinase activity MF
GO:0006468 protein phosphorylation BP
GO:0005516 calmodulin binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values