General information for g267.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Alpha-1,3-fucosyltransferase C.
Parent gene
- The parent gene g267 is located on chr_3: 2166147..2167537 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g267 | g267.t1 | isoform | g267.t1 | 2166147 | 2167537 |
| chr_3 | g267 | g267.t1 | exon | g267.t1.exon1 | 2166147 | 2166595 |
| chr_3 | g267 | g267.t1 | cds | g267.t1.CDS1 | 2166147 | 2166595 |
| chr_3 | g267 | g267.t1 | exon | g267.t1.exon2 | 2166650 | 2166828 |
| chr_3 | g267 | g267.t1 | cds | g267.t1.CDS2 | 2166650 | 2166828 |
| chr_3 | g267 | g267.t1 | exon | g267.t1.exon3 | 2166927 | 2167537 |
| chr_3 | g267 | g267.t1 | cds | g267.t1.CDS3 | 2166927 | 2167537 |
| chr_3 | g267 | g267.t1 | TTS | g267.t1 | 2167722 | 2167722 |
| chr_3 | g267 | g267.t1 | TSS | g267.t1 | NA | NA |
Sequences
>g267.t1 Gene=g267 Length=1239
ATGTCACATTATTCTGACAGATTCAAATTAGGTCCAGAAAAAAATGTTAAACCACTTTCA
CTTTCAACGAAAGGAAAGAAATTTTTCACTTATCTTTTAATTGCATCAATCGTGATTTTA
TTTTATTTTGCATCATTAAGAAATTTCACTGCAGATGAAAACATTTTCTTAAGACCATTT
ATTGTAAAGCCAAAACCAATGAAAAACATTTTATTTTGGTCTAAATATTTCGGTGATACA
ACTTGGTATTCTGGAAGTGATGAAGCTGGCAAAGAAGTTTTAAAATCAGTTGAATGTCCA
GTTACAAATTGCTTTTTTACACATGATTATAATTTTCTAGATAATGTCACAAAATTTGAT
GCAATTGCATTTCATGGACCTGAACTTATAAGAAATATTGTTCCTTTAAATAGAAATCAA
AATCAAATTTATATTTTTGTTGATTTAGAAGCTCCAACTGCCGTGAGAGATTTATCAGAA
TTTGAAAACTTTTTCAATCTTACAATGCATTATCGACTTGATTCTGACATTGAATTTGAC
TATGGGAAAGTTGTGGCAATAAATTCAGTCAAAGCTATTGCTCCTTCTAAAAATCCTAAT
TGGATGAAAGTTGATGAAGATTTTTATGATGAAGAATTTTTAAAAATCTTTGAGAAAAAG
AAGAAAAACATTGCCTGGTTTGTATCACATTGTGAAACATTTTCAAGACGTGAACTTTTA
GTTGAGCATATGCAAAATTTTACAACAATTGATATTTATGGTCAATGTGGTCCATTCAAA
TGTCCAAGATTTTCAGATAAATGTTCAAAAATGTTGACTGATGATTACAAATTTTATTTA
TCATTTGAAAATTCTTTATGTGATGATTATGTAACTGAAAAATTATTTAATTCAATGACT
GAATTTGTAATTCCAATTGTCTTTAATGGTGCCAACATGAATAATTTTCTCCCACCAAAA
TCTTATATTAATGCCAATGATTTTGAAACTGTTGAAGATCTTGTTGATTATCTAAATTTT
TTAAGTGAAAATCCTAAAGAATACATCAAATATTTTTGGTGGAGGCAATATTATAAAATT
TTACCTCATCCAGTTTTTTCTTATGCTCTCTGTGATATTTGTAAGAAATTAAATGATGAA
AATTTCATAGAAACACGGCATATTTATACTGATCTTAATTCTTGGTTTAGAGATAAAAAA
TGCAACCAACAAGCTCACATAAAGTTCAGAAATTTATGA
>g267.t1 Gene=g267 Length=412
MSHYSDRFKLGPEKNVKPLSLSTKGKKFFTYLLIASIVILFYFASLRNFTADENIFLRPF
IVKPKPMKNILFWSKYFGDTTWYSGSDEAGKEVLKSVECPVTNCFFTHDYNFLDNVTKFD
AIAFHGPELIRNIVPLNRNQNQIYIFVDLEAPTAVRDLSEFENFFNLTMHYRLDSDIEFD
YGKVVAINSVKAIAPSKNPNWMKVDEDFYDEEFLKIFEKKKKNIAWFVSHCETFSRRELL
VEHMQNFTTIDIYGQCGPFKCPRFSDKCSKMLTDDYKFYLSFENSLCDDYVTEKLFNSMT
EFVIPIVFNGANMNNFLPPKSYINANDFETVEDLVDYLNFLSENPKEYIKYFWWRQYYKI
LPHPVFSYALCDICKKLNDENFIETRHIYTDLNSWFRDKKCNQQAHIKFRNL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g267.t1 | Gene3D | G3DSA:3.40.50.11660 | - | 156 | 367 | 7.3E-38 |
| 3 | g267.t1 | PANTHER | PTHR11929:SF217 | ALPHA 1,3 FUCOSYLTRANSFERASE-RELATED | 65 | 405 | 8.3E-102 |
| 4 | g267.t1 | PANTHER | PTHR11929 | ALPHA- 1,3 -FUCOSYLTRANSFERASE | 65 | 405 | 8.3E-102 |
| 2 | g267.t1 | Pfam | PF17039 | Fucosyltransferase, N-terminal | 67 | 182 | 1.8E-22 |
| 1 | g267.t1 | Pfam | PF00852 | Glycosyltransferase family 10 (fucosyltransferase) C-term | 220 | 396 | 4.6E-59 |
| 8 | g267.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 27 | - |
| 10 | g267.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 28 | 46 | - |
| 9 | g267.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 47 | 412 | - |
| 6 | g267.t1 | SUPERFAMILY | SSF53756 | UDP-Glycosyltransferase/glycogen phosphorylase | 54 | 397 | 1.44E-81 |
| 5 | g267.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 29 | 51 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0008417 | fucosyltransferase activity | MF |
| GO:0006486 | protein glycosylation | BP |
KEGG
Orthology
- This transcript has been annotated with K14464 (alpha-1,3-fucosyltransferase [EC:2.4.1.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed