General information for g2727.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine/threonine-protein kinase Tao.
Parent gene
- The parent gene g2727 is located on chr_3: 19908534..19911408 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2727 | g2727.t1 | isoform | g2727.t1 | 19905148 | 19908718 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon1 | 19905148 | 19905710 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS1 | 19905148 | 19905710 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon2 | 19905793 | 19906122 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS2 | 19905793 | 19906122 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon3 | 19906181 | 19907194 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS3 | 19906181 | 19907194 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon4 | 19907262 | 19907412 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS4 | 19907262 | 19907412 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon5 | 19907475 | 19907547 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS5 | 19907475 | 19907547 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon6 | 19907607 | 19907656 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS6 | 19907607 | 19907656 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon7 | 19907718 | 19907834 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS7 | 19907718 | 19907834 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon8 | 19907900 | 19908073 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS8 | 19907900 | 19908073 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon9 | 19908134 | 19908355 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS9 | 19908134 | 19908355 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon10 | 19908416 | 19908534 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS10 | 19908416 | 19908534 |
| chr_3 | g2727 | g2727.t1 | exon | g2727.t1.exon11 | 19908595 | 19908718 |
| chr_3 | g2727 | g2727.t1 | cds | g2727.t1.CDS11 | 19908595 | 19908718 |
| chr_3 | g2727 | g2727.t1 | TSS | g2727.t1 | NA | NA |
| chr_3 | g2727 | g2727.t1 | TTS | g2727.t1 | NA | NA |
Sequences
>g2727.t1 Gene=g2727 Length=2937
ATGGCGCCTGCACCTCGTCCTGGTAGTCTCAAAGATCCCGAGATCGCAGAACTCTTCAAC
AAGCATGATCCGGATAAAATATTCGAAGATTTGCGAGAAATTGGACATGGATCTTTTGGT
GCTGTATATTATGCACGATGCAATCTTACACGAGAGATTGTAGCTATTAAGAAAATGTCC
TATCTGGGAAAACAAAGTTTAGAAAAGTGGCAAGACATTCTAAAAGAAATTCGTTTCCTG
CGTCAATTAAATCATCCGAATACAATAGAGTATAAGGGATGTTATTTGCATGAAAATACA
GCATGGCTCGTGATGGAATATTGTGTTGGATCTGCTTCAGATATTATTGAAGTTCATAAG
CGACCTTTGAAGGAGGATGAGATTGCAGCAATTTGTGATGGAGTATTACATGGACTGAGT
TACTTGCATCTTTTGGGACGAATTCATAGAGACATCAAAGCGGGAAATATTTTATTAACT
GAACAGGGTGTTGTCAAATTAGCAGATTTTGGAAGTGCTGCTATAAAATGTCCTGCAAAT
TCTTTTGTTGGTACACCATATTGGATGGCACCTGAAGTTATTTTAGCAATGGACGAGGGT
CAATACGATGGAAAAGTGGATGTGTGGTCATGCGGAATAACATGCATTGAGTTAGCTGAG
AGAAAACCACCTTATTTTAATATGAATGCCATGTCTGCTCTTTATCATATTGCCCAAAAT
GATGCGCCCATTCTACAAGTTCAAACACCCGATTGGTCTCATCTATTTAGAAATTTTGTT
GAAGTATGTTTGAAAAAATCACCTCTGGATCGACCCACTTCAAGTGAACTTCTTGCTCAC
GCATTTGTATCTCGACAACGTTCACCAACTGTTCTCGTAGATTTGATTGCTAGAACAAAA
GCAGCAGTTCGTGAGTTGGACAATTTAAATTACCGTAAAATGAAAAAAATTCTAATGGTT
GACAATTGTGAAACTGAAAGTAATGTGGGTGATGCAGATGATACGCCGGATGATCAAGTT
GGTGGTGACAGTAGTAAGAGCAACAGTATCACATCTGAACATTCAATGCAATCAATCGGC
GGTATAGTTCCAAATAGTCAAAGTTCTTCTAGTAATTCAATTCCACCAAACCAAATTGAT
CAGCAAGGTAATTTGCATCGAAATTCCTCGCGACATCGACTACCAATGGCATTGCCACAG
CATCAACCGCAGTACGTAAATGCAATGGCTGCTGCAGCAGTAGCAGCAGGTTCAGGTCAT
CATATGTCTAGTAATTATGCAAATCATCATCACCATCATCATGCACAACAGCAAGCTCAC
ATGCAAGCATCAGCCTCAGGAACGAGTACGACATCAAGAGAACATCAACATCATCATCAA
ATGCAACAAATGTATGGAGGCATGCATCATAATCAAGCAAATCAAGCTGCAGTCAATGCT
ATCGCGGAGCATGGACCAAATAATTTTGCAACAATTCGAACAACAAGTATCGTAACAAAA
CAGCAAAAAGAGCATATGCAAGAAGATATGCATGAACAAATGTCAGGCTATAAACGAATG
AGACGTGAACATCAGGCTGCTTTATTAAAATTAGAAGAAAAATGTAAAGTTGAAATGGAA
GCTCATAAAGCTGCTTTAGATAAAGAGTACGATTTATTGCTACATAATTTTACAAGAGAA
TTAGAAAAACTCGCAGTCAAGCATCAGCAAGAACTCGAAAAGAGAGTAAAGCAAAATAAC
GTTGCTGAAAAGAAGCTCTTTAAAGAAATTCAGTTACGTCAAGAGGGTGACAGAAAAGCA
TTCGATACTCATCGTAAAAAAGAGTATAAGGCTAACAAAGAAAGATGGAAGCGAGAGCTT
TCAATGGATGATACAACGCCAAAAAGGCAAAGAGATGCCACTCTACAGTCTCAAAAGGAG
AATTTGAAAATGGCTGAAGCAGCCGAAGAGCAACGACTCCTTCGAGTACAGAAAAATTAT
ATTGAATTGGAAATGCGCAAATTTAAACGAAAAAAGATGTGTTCACTTCATGATTTAGAA
AATCAACTGTTGAGAGATGAGCTAAGTAAGAAACAACAGCAACTTGAACAAGCCCATGCC
ATGCTATTGAGACATCATGAAAAAACACAAGATCTTGAATATAAGCAGCAACGGAATGTT
CACTCTCTTAGGGAAGACCAGATTTGCAACCAACATGAAAGTGAATTGAAAAATCAAAAG
GATTATATGGAGCGTGCTGAACGCGAATTATTGCGTAAACACGCAACTGAATTGAAACAG
CAACCTAAAAGTCTCAAACAAAAGGAGCTTCAAATATGGAAACAGTTTCGTGAAACTTGC
AAAACACAAACACGCCAATATAAGGCATTAAAAGCACAAATTCTGCAAACAACACCTAAA
GATGAGCAAAAAGCTGTGATAAAGAAATTAAAGGAGGAACAACAACGAAAATTGGCACTT
CTCGGTGATCAATATGAACAAAGTATTAATGATATGCTGCAAAAACAGTCATTGCGTTTA
GATGAGAGTCAAGAGGGTGAATGTGCTCAATTGAGAGATCGTTTGCAATATGAGCTGAAT
ATTTTGACAGCGTATCAGGAAAAGAATAGATTGCAGGCTCAGTCTCAACGTGATCGAGAA
AGAAAAGAATTGGAAGAACGTGTGAGCGTTCGAAGAGCATTGCTTGAGAGCAAGATGGAA
ACAGAATTGCAACAATTTAATCAAGAGCGATCTGAACGAATTCGTTTATTAAGAGAGAAA
CAAGATCGACAATTAGAGCAATTCGATGTTGAATCTGCTAACATGGGTTTCAGTGCTCTT
GCATTGGCTGAAGCAAGTCAAGAAACTTATCCAGAAGAAGAAGGAAGTTTGAGTGGAAGT
ATGTTATCTCTTGCTCACAGCAATTCATCTACAAGTTTTCCGGCTGGTTCGCTATAG
>g2727.t1 Gene=g2727 Length=978
MAPAPRPGSLKDPEIAELFNKHDPDKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMS
YLGKQSLEKWQDILKEIRFLRQLNHPNTIEYKGCYLHENTAWLVMEYCVGSASDIIEVHK
RPLKEDEIAAICDGVLHGLSYLHLLGRIHRDIKAGNILLTEQGVVKLADFGSAAIKCPAN
SFVGTPYWMAPEVILAMDEGQYDGKVDVWSCGITCIELAERKPPYFNMNAMSALYHIAQN
DAPILQVQTPDWSHLFRNFVEVCLKKSPLDRPTSSELLAHAFVSRQRSPTVLVDLIARTK
AAVRELDNLNYRKMKKILMVDNCETESNVGDADDTPDDQVGGDSSKSNSITSEHSMQSIG
GIVPNSQSSSSNSIPPNQIDQQGNLHRNSSRHRLPMALPQHQPQYVNAMAAAAVAAGSGH
HMSSNYANHHHHHHAQQQAHMQASASGTSTTSREHQHHHQMQQMYGGMHHNQANQAAVNA
IAEHGPNNFATIRTTSIVTKQQKEHMQEDMHEQMSGYKRMRREHQAALLKLEEKCKVEME
AHKAALDKEYDLLLHNFTRELEKLAVKHQQELEKRVKQNNVAEKKLFKEIQLRQEGDRKA
FDTHRKKEYKANKERWKRELSMDDTTPKRQRDATLQSQKENLKMAEAAEEQRLLRVQKNY
IELEMRKFKRKKMCSLHDLENQLLRDELSKKQQQLEQAHAMLLRHHEKTQDLEYKQQRNV
HSLREDQICNQHESELKNQKDYMERAERELLRKHATELKQQPKSLKQKELQIWKQFRETC
KTQTRQYKALKAQILQTTPKDEQKAVIKKLKEEQQRKLALLGDQYEQSINDMLQKQSLRL
DESQEGECAQLRDRLQYELNILTAYQEKNRLQAQSQRDRERKELEERVSVRRALLESKME
TELQQFNQERSERIRLLREKQDRQLEQFDVESANMGFSALALAEASQETYPEEEGSLSGS
MLSLAHSNSSTSFPAGSL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g2727.t1 | CDD | cd06607 | STKc_TAO | 26 | 285 | 0.0 |
| 6 | g2727.t1 | Coils | Coil | Coil | 514 | 534 | - |
| 9 | g2727.t1 | Coils | Coil | Coil | 554 | 574 | - |
| 8 | g2727.t1 | Coils | Coil | Coil | 676 | 701 | - |
| 7 | g2727.t1 | Coils | Coil | Coil | 729 | 749 | - |
| 4 | g2727.t1 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 12 | 107 | 2.0E-33 |
| 5 | g2727.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 108 | 322 | 4.2E-61 |
| 15 | g2727.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 328 | 357 | - |
| 19 | g2727.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 341 | 357 | - |
| 14 | g2727.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 428 | 462 | - |
| 13 | g2727.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 597 | 636 | - |
| 18 | g2727.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 597 | 637 | - |
| 16 | g2727.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 944 | 978 | - |
| 17 | g2727.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 951 | 978 | - |
| 2 | g2727.t1 | PANTHER | PTHR47167 | SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN | 1 | 963 | 0.0 |
| 1 | g2727.t1 | Pfam | PF00069 | Protein kinase domain | 28 | 282 | 1.4E-61 |
| 12 | g2727.t1 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 34 | 58 | - |
| 20 | g2727.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 28 | 283 | 45.644 |
| 11 | g2727.t1 | SMART | SM00220 | serkin_6 | 28 | 283 | 8.4E-85 |
| 3 | g2727.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 28 | 284 | 1.89E-80 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K04429 (thousand and one amino acid protein kinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
