General information for g2727.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine/threonine-protein kinase Tao.
Parent gene
- The parent gene g2727 is located on chr_3: 19908534..19911408 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2727 | g2727.t3 | isoform | g2727.t3 | 19903200 | 19906122 |
| chr_3 | g2727 | g2727.t3 | exon | g2727.t3.exon1 | 19903200 | 19903579 |
| chr_3 | g2727 | g2727.t3 | exon | g2727.t3.exon2 | 19904864 | 19905710 |
| chr_3 | g2727 | g2727.t3 | cds | g2727.t3.CDS1 | 19905148 | 19905710 |
| chr_3 | g2727 | g2727.t3 | exon | g2727.t3.exon3 | 19905793 | 19906122 |
| chr_3 | g2727 | g2727.t3 | cds | g2727.t3.CDS2 | 19905793 | 19906120 |
| chr_3 | g2727 | g2727.t3 | TTS | g2727.t3 | 19906222 | 19906222 |
| chr_3 | g2727 | g2727.t3 | TSS | g2727.t3 | NA | NA |
Sequences
>g2727.t3 Gene=g2727 Length=1557
CGTATATATTTTACTTTAAAATAAATTCTGTATACCATTGGTATATATGCATGAGTAAGT
GACACCCGCAAATAGTGTTTCTATACATAAAAGTGTTATTTCCCCTAGAGGGGCTTTGTC
GATTTTTCACTTCATTTTTTCAAAAGTTGAGAGAAATAAAAAATTTGCAAATGAACACAA
AATCAGTGAAAAATTAAGACAAAAAACTACGAGAAGGACTCTAATAAAGACAAAGAAATT
GAACAAATGGATAGAAAAGAGTCCAGGCATGAAAGAAAAGTGAAAAATTGAAAGTAATAG
TTTGAATGAAAAAAATGGGCTGGATTAAATTTTTTTTGAAAAAATAAAAAAGTAGAATCA
TTAGTGTTTCAAAATATCAGAAAATATGACGATATTGGAATAGCGCGAAAGTAAATCATC
AATCTTTTCTTCAATCTCTCCTTTTTGAATGCCAAATATATAAATTTATTTCATTATAAT
AGTGTATACAATAATACCTTGAAAAAGAGAAGAAAATCGATAAAATTCATTGTGAATGAA
TACATGACAATAAGAAGTTATAAAAGAATCTATCAAAACATAAGGATTGCGATTATTATC
ATCATCAATTAAACGCCGAATAAAAAAGTGTTAGGTGAAAATTATTCATTAAAGAGAAGA
AGAAATGGCGCCTGCACCTCGTCCTGGTAGTCTCAAAGATCCCGAGATCGCAGAACTCTT
CAACAAGCATGATCCGGATAAAATATTCGAAGATTTGCGAGAAATTGGACATGGATCTTT
TGGTGCTGTATATTATGCACGATGCAATCTTACACGAGAGATTGTAGCTATTAAGAAAAT
GTCCTATCTGGGAAAACAAAGTTTAGAAAAGTGGCAAGACATTCTAAAAGAAATTCGTTT
CCTGCGTCAATTAAATCATCCGAATACAATAGAGTATAAGGGATGTTATTTGCATGAAAA
TACAGCATGGCTCGTGATGGAATATTGTGTTGGATCTGCTTCAGATATTATTGAAGTTCA
TAAGCGACCTTTGAAGGAGGATGAGATTGCAGCAATTTGTGATGGAGTATTACATGGACT
GAGTTACTTGCATCTTTTGGGACGAATTCATAGAGACATCAAAGCGGGAAATATTTTATT
AACTGAACAGGGTGTTGTCAAATTAGCAGATTTTGGAAGTGCTGCTATAAAATGTCCTGC
AAATTCTTTTGTTGGTACACCATATTGGATGGCACCTGAAGTTATTTTAGCAATGGACGA
GGGTCAATACGATGGAAAAGTGGATGTGTGGTCATGCGGAATAACATGCATTGAGTTAGC
TGAGAGAAAACCACCTTATTTTAATATGAATGCCATGTCTGCTCTTTATCATATTGCCCA
AAATGATGCGCCCATTCTACAAGTTCAAACACCCGATTGGTCTCATCTATTTAGAAATTT
TGTTGAAGTATGTTTGAAAAAATCACCTCTGGATCGACCCACTTCAAGTGAACTTCTTGC
TCACGCATTTGTATCTCGACAACGTTCACCAACTGTTCTCGTAGATTTGATTGCTAG
>g2727.t3 Gene=g2727 Length=297
MAPAPRPGSLKDPEIAELFNKHDPDKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMS
YLGKQSLEKWQDILKEIRFLRQLNHPNTIEYKGCYLHENTAWLVMEYCVGSASDIIEVHK
RPLKEDEIAAICDGVLHGLSYLHLLGRIHRDIKAGNILLTEQGVVKLADFGSAAIKCPAN
SFVGTPYWMAPEVILAMDEGQYDGKVDVWSCGITCIELAERKPPYFNMNAMSALYHIAQN
DAPILQVQTPDWSHLFRNFVEVCLKKSPLDRPTSSELLAHAFVSRQRSPTVLVDLIA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g2727.t3 | CDD | cd06607 | STKc_TAO | 26 | 285 | 0.0 |
| 4 | g2727.t3 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 12 | 107 | 2.9E-34 |
| 5 | g2727.t3 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 108 | 297 | 3.2E-59 |
| 2 | g2727.t3 | PANTHER | PTHR47167 | SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN | 1 | 296 | 1.3E-183 |
| 6 | g2727.t3 | PIRSF | PIRSF000654 | ILK | 6 | 281 | 6.2E-28 |
| 1 | g2727.t3 | Pfam | PF00069 | Protein kinase domain | 28 | 282 | 7.1E-63 |
| 8 | g2727.t3 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 34 | 58 | - |
| 10 | g2727.t3 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 28 | 283 | 45.644 |
| 9 | g2727.t3 | SMART | SM00220 | serkin_6 | 28 | 283 | 8.4E-85 |
| 3 | g2727.t3 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 24 | 290 | 1.3E-80 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
