General information for g275.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as PX domain-containing protein kinase-like protein.
Parent gene
- The parent gene g275 is located on chr_3: 2371470..2372133 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g275 | g275.t1 | isoform | g275.t1 | 2369210 | 2371470 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon1 | 2369210 | 2369225 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS1 | 2369210 | 2369225 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon2 | 2369597 | 2369656 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS2 | 2369597 | 2369656 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon3 | 2369841 | 2369882 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS3 | 2369841 | 2369882 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon4 | 2369982 | 2370588 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS4 | 2369982 | 2370588 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon5 | 2370648 | 2370796 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS5 | 2370648 | 2370796 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon6 | 2370852 | 2371084 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS6 | 2370852 | 2371084 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon7 | 2371156 | 2371242 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS7 | 2371156 | 2371242 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon8 | 2371300 | 2371396 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS8 | 2371300 | 2371396 |
| chr_3 | g275 | g275.t1 | exon | g275.t1.exon9 | 2371460 | 2371470 |
| chr_3 | g275 | g275.t1 | cds | g275.t1.CDS9 | 2371460 | 2371470 |
| chr_3 | g275 | g275.t1 | TTS | g275.t1 | 2371573 | 2371573 |
| chr_3 | g275 | g275.t1 | TSS | g275.t1 | NA | NA |
Sequences
>g275.t1 Gene=g275 Length=1302
ATGAATACAATCTTAGCATCGTCATTACCAACAAAAAAATTCATCGATCCAGATTCAATC
TCAATTCCATTTCATGATATTGCACATCAAAATGTGACAGCTTTATTGAAGAACGATAGT
GCATGGATATTGAAAAACTCTGTTGGACCTATTGGTTGGCGCGCTCGTAAACATTTTTTT
AAAGTCTCCCAAAAGACTCACACATGTCAGAAGCATAGCCAATTATCGAAGCTCGAGTCG
CAAGCGAGCACGTCAAGTTATAAAGAAGGCTCGAATAGTGATACTGAATATTTATGTAGT
TGGATTGAATTTGGTCAAGATAAATATGTTAACGATAAAGAACTTAATACAATTTTGAAG
AGTCTGGCATCAATTAAGCATCCATTTCTTTATCCAATTGAATATATTCAAGCGAATGAG
AATGGATGTATGGTTATTGTGAAATATCATAAGAAAGGAAGCCTAAAAGATTTGTTGTGT
GGTTGCGACAATCCATTGAATACTTTTTCATCAAAATATGGTACTACTAAAGGACGTATG
GTCAATGGACTGCCACTTAAAGATCTTGCAATGTATAGCAGACAAATTTTAGAGGCGATA
AGATTCTTACATTCTAAAGGCCTTCCATATGGACATCTTACTACGGCCAATATATTCATT
GACAAAGGAATTGCAAAATTGAGTGCTATTGAAAATTTTCTGTTAGGTGTTCCATCTTTT
TATCGGCCATTCTTCGTTCAAAATAACAAAATTCAAACGATGGAACAAGTCGATTTGTTT
ACCTTTGGCCATGTTGTTTTTGAAATGCAGTCAACATATTCACTGCAAGAACCATTTATT
CGTTCGGAAATTACTGATTGTCCTGTAGCTTTAAAATCCTTTTTGGAGATGATGATATCG
AAAGAATCATTAAAGTCAAATTTTGTAACAATGGAGCAAATTTTAAAACATCAGTTTTTT
ACTGAATTTGCGCAGTCATATACGAAGTTTCATGCGGAAGTAGAAGACATTATAAAGAAA
GCGTCAGCTGCAGATATTCATGGAAAAGATTTAATTGCAACAGTTGTTCAGAAGACAGAA
CAACGGTTAAAGGATGAACAGAAATTGGTTAAAAGTCAGAAACGTGTTGTTAGAGTTCAA
AACGAAATGATGACTTCAGGAGAAGAGGAAAAAAAGAAACAAATTAAACAAAAGTTAAAA
TCTCAATCATCACTTCAAAACGGACCAATAAATTTTAAGTTGAGCCTCTCTGAAAGTAGT
CAAGAGCAAGCTGAGAATTCCTCACCGAAAGATACTCGCTGA
>g275.t1 Gene=g275 Length=433
MNTILASSLPTKKFIDPDSISIPFHDIAHQNVTALLKNDSAWILKNSVGPIGWRARKHFF
KVSQKTHTCQKHSQLSKLESQASTSSYKEGSNSDTEYLCSWIEFGQDKYVNDKELNTILK
SLASIKHPFLYPIEYIQANENGCMVIVKYHKKGSLKDLLCGCDNPLNTFSSKYGTTKGRM
VNGLPLKDLAMYSRQILEAIRFLHSKGLPYGHLTTANIFIDKGIAKLSAIENFLLGVPSF
YRPFFVQNNKIQTMEQVDLFTFGHVVFEMQSTYSLQEPFIRSEITDCPVALKSFLEMMIS
KESLKSNFVTMEQILKHQFFTEFAQSYTKFHAEVEDIIKKASAADIHGKDLIATVVQKTE
QRLKDEQKLVKSQKRVVRVQNEMMTSGEEEKKKQIKQKLKSQSSLQNGPINFKLSLSESS
QEQAENSSPKDTR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g275.t1 | CDD | cd00180 | PKc | 97 | 317 | 2.23785E-15 |
| 6 | g275.t1 | Coils | Coil | Coil | 356 | 376 | - |
| 5 | g275.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 89 | 359 | 4.1E-16 |
| 9 | g275.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 381 | 433 | - |
| 8 | g275.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 399 | 427 | - |
| 2 | g275.t1 | PANTHER | PTHR22999:SF18 | PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN | 1 | 428 | 5.3E-90 |
| 3 | g275.t1 | PANTHER | PTHR22999 | PX SERINE/THREONINE KINASE PXK | 1 | 428 | 5.3E-90 |
| 1 | g275.t1 | Pfam | PF07714 | Protein tyrosine and serine/threonine kinase | 113 | 226 | 7.0E-6 |
| 10 | g275.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 45 | 363 | 11.906 |
| 4 | g275.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 110 | 325 | 1.46E-20 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K17543 (PX domain-containing protein kinase-like protein)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
