Gene loci information

Transcript annotation

  • This transcript has been annotated as DNA polymerase iota.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2750 g2750.t3 TSS g2750.t3 19976885 19976885
chr_3 g2750 g2750.t3 isoform g2750.t3 19977510 19981098
chr_3 g2750 g2750.t3 exon g2750.t3.exon1 19977510 19977924
chr_3 g2750 g2750.t3 exon g2750.t3.exon2 19977986 19978327
chr_3 g2750 g2750.t3 exon g2750.t3.exon3 19979783 19979948
chr_3 g2750 g2750.t3 exon g2750.t3.exon4 19980016 19980677
chr_3 g2750 g2750.t3 cds g2750.t3.CDS1 19980035 19980677
chr_3 g2750 g2750.t3 exon g2750.t3.exon5 19980953 19981098
chr_3 g2750 g2750.t3 cds g2750.t3.CDS2 19980953 19980963
chr_3 g2750 g2750.t3 TTS g2750.t3 19981358 19981358

Sequences

>g2750.t3 Gene=g2750 Length=1731
ATTTTTTTATTTTTCCTTGGTTTTAGATTTTTCATAATATACTGTTCGAAATCATGCTAT
AATATTAACAGAAAAATTTGATTTGATGAAAATAGGACATAAACAAATTTATTTTTATCT
GAATTTTTAATGGCTCAGAAGTAATTTTAAAAAATAAACACATAAGTTGACGAAAAATTT
ATGAAGAAGTTAAATAAAAAACCCAATTTACTTTTCTTCACACCAGGTGTTTTCTTTACG
AACTTGTTCTTCTTCAGCTGGTGAAAAGTCATTCTTAATGTTAAACGTCTTGCGGATTTC
ATCTGGTGTCTTTCCTTTAATCATATTTGCAACAGTCTTGCATGTAACATCCAAAAGACT
TCGAATGTCTAAATAATTTGCTGCGAGAATAAGTTCAAATAATGTTCCTTGATCGACCTT
TAAGAAATCTGCATCCCATGATGTGATATCATCAGTACGCTTTTCCTTATTTTCGTCATC
ATCGGTACTCGATGGAACTGGATCATCTTTATGATAAGTGCAAAATTGAATCACTTTACG
AAGAATAGCCGAATTAACATTTGGAAGAGGAACAACTTCATCCTCACTGGATTCATCGAT
TCCTAAATCCTCCAGCATTGTTCGAATTGTTCCAGAGCACTTAGCAACAGCTAAATCGCA
TTCGAAAATTTCACTGTCAGATGATTGTAATTTGATGTTTTGCATTTTTTAGGAGTTTAT
TTTTAAAATAGCTCTATGTAAAAAGTGAAGTTTTGAACTTACTTGTTCAGTAGGAATAGC
TCATAATAAATTATTATCAAAGCTTGTAGGTCAAATGAACAAGCCTAATAATCAAACAGT
TTTAGCACCTACAGCAGCAAAAGCATTCATGTGTGAACTTCGTAATCTTCGCAGTATTAC
AGGTATTGGTGAGAAGACGGCAGAAAGAAATTTGGAAACGATATGGCACAGCGACTTAAA
GAAATGTCTCTCGGAATAGATTCATCTGATTTTAAACCATCTGGAAAGCCAAAAACAGTC
GGTCTCGAAGACTCATTTCGTCCAATCTCAATTCGTAGTGATGCAGCAGAAAAATTTCAT
GCTCTCTTATCTCGACTTATGATACAAATCCAAGATGACGGTAGAGTGCCACAGTCGATA
AAAGTAACAGTGAGGAAATATGATCCAGCAAAGAAAAACAGTATTCGTGAGACGAAACAA
TGTACATTAGCACCATCACTCTTTCGATGTAGTGATGGTAAAATTCAATTAACAGAAGGT
GCTGAACAAAAAATTATCAAGAATGTATTGATGCTTTTCGATCGAATGGTTGATTTGAAG
CAACAGTTTAATATTACACTATTAGGGTTGTGCTTTAGCAAATTTCAAGAACAGAAACGT
GGTCCAGCATCAATTGCAAACTACCTTATGAAGAAGCAAGATGTTGAGGTACAATCAATA
ACGAATTTAAGTAATGAAACATGTAGTTCATTTAATGATAGCTTCAGATCAAAAACTGCT
TCACCATCTTCATCATTAATGGACTTTGAAACAATATCTAACAATTCATTAGACTTATCG
GGTTCAGAAGAATCGGAAGAGCCTTACATACCATGAATGTTGTGTTGATTTTCCTTTATA
GTGTGGCAGGAGCTTCCACTAGATGTCCAACGTGAATTAATGATGAATTGGCAGACAACT
ACTTCTGCTCCTTCGTCTACAACTGGCACAACATCCATTCCAAAAACAAAA

>g2750.t3 Gene=g2750 Length=217
MAQRLKEMSLGIDSSDFKPSGKPKTVGLEDSFRPISIRSDAAEKFHALLSRLMIQIQDDG
RVPQSIKVTVRKYDPAKKNSIRETKQCTLAPSLFRCSDGKIQLTEGAEQKIIKNVLMLFD
RMVDLKQQFNITLLGLCFSKFQEQKRGPASIANYLMKKQDVEVQSITNLSNETCSSFNDS
FRSKTASPSSSLMDFETISNNSLDLSGSEESEEPYIP

Protein features from InterProScan

Transcript Database ID Name Start End E.value
4 g2750.t3 Gene3D G3DSA:3.30.1490.100 - 23 147 0
2 g2750.t3 PANTHER PTHR46404 DNA POLYMERASE IOTA 2 187 0
1 g2750.t3 Pfam PF11799 impB/mucB/samB family C-terminal domain 19 144 0
3 g2750.t3 SUPERFAMILY SSF100879 Lesion bypass DNA polymerase (Y-family), little finger domain 24 142 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006281 DNA repair BP
GO:0003684 damaged DNA binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed