General information for g2763.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Lutropin-choriogonadotropic hormone receptor.
Parent gene
- The parent gene g2763 is located on chr_3: 20065044..20069178 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2763 | g2763.t1 | isoform | g2763.t1 | 20065044 | 20069178 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon1 | 20065044 | 20065340 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS1 | 20065044 | 20065340 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon2 | 20065398 | 20065546 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS2 | 20065398 | 20065546 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon3 | 20065610 | 20065684 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS3 | 20065610 | 20065684 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon4 | 20065755 | 20065832 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS4 | 20065755 | 20065832 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon5 | 20066220 | 20066297 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS5 | 20066220 | 20066297 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon6 | 20066472 | 20066537 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS6 | 20066472 | 20066537 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon7 | 20066602 | 20066670 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS7 | 20066602 | 20066670 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon8 | 20066739 | 20066813 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS8 | 20066739 | 20066813 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon9 | 20066872 | 20066989 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS9 | 20066872 | 20066989 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon10 | 20067052 | 20067452 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS10 | 20067052 | 20067452 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon11 | 20067519 | 20067613 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS11 | 20067519 | 20067613 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon12 | 20067684 | 20067884 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS12 | 20067684 | 20067884 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon13 | 20067962 | 20068190 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS13 | 20067962 | 20068190 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon14 | 20068409 | 20068464 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS14 | 20068409 | 20068464 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon15 | 20068532 | 20068677 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS15 | 20068532 | 20068677 |
| chr_3 | g2763 | g2763.t1 | exon | g2763.t1.exon16 | 20068741 | 20069178 |
| chr_3 | g2763 | g2763.t1 | cds | g2763.t1.CDS16 | 20068741 | 20069178 |
| chr_3 | g2763 | g2763.t1 | TSS | g2763.t1 | NA | NA |
| chr_3 | g2763 | g2763.t1 | TTS | g2763.t1 | NA | NA |
Sequences
>g2763.t1 Gene=g2763 Length=2571
ATGAAAATTGTGAAAAACACTTTAAAGTACAAATGGAAAATTTTATTTTTATTGTGCAAT
TGGATAAACTTTTTTATTACATCTTCATTCTATTTTAAATTTGCTGAGTGTGAAGTCTCA
TCGTCCACATATTTGGATCGAATAAAGTTTATGAATGAGAATTCAACATTTTTATACTCG
CTAATTAACACTAATGTCACAAAAACACCGCTAACTAATTTCACTGCAAATGATGAAATT
TCTGAACCCTGGAGATGTTTGTGTTCTAACGGATTGGAAGATCAGGACGCAAAAAATGGT
GAAATCGAATGCCATTGTGAGGGATTACCATTAAAAAATATTCCACAAAATCTCTTCAAT
TTTACAAGACTGTCTGTAGTAAATACAAATTTAAAACAATTGAGGGAAAGTGAATTAAGA
AAATATGCAGCCTTTATAAAAGATATATCATTAACAAATTTGAATGAATTTGAGAAAATT
GATTCAGATGCTTTCAAAAATACACGTCAATTACGAGCACTTGAGATTTCGCACGCCCCA
AAGCTCAAATCTATTGATAAAGAAACATTTCAGTATGTTACATATTCCTTCAAGATACTA
CGGATTGTTCACTCAGGCTTAGAACAAATCCCTGATGTAAGCTTCCTGCAGATAAATACG
AAAATTTTATTACAATTAGACTTTGAAGGAAACCAAATAACCAAAATTCCTGAAAATTCC
ATTCAGATAAGAACTGAACAATTAATTCTCGACAATAACAAACTAACAAAGGTAGAAAAG
GCAGCTTTTAATGGATCTGAAATTGGAAAATTGAGTTTAAAGGGCAATACAAAATTGCGA
TTTCTGCATGTGCGTGCATTTGAGGGAATTAAAAACATCAGAGAATTAGATTTGTCGAGT
ACATTTATTGAAAGCTTACCCACGCTTGGACTTAATAAATTAGAAACACTTCGCATACAA
AATACTCGATCATTGAAGCATATTCCATCCGTTTTTGAACTTATGAATCTTGAAAAGGCA
TGGCTCACTCATTCCTTTCATTGTTGTGCATTTAAATTTCCACAACGACATGATCCTACT
CGTCATGAAAAGCACTTGCAGCTTATTGAAAGTTTCAAAAATGAATGCAAAGAGAAGGGC
TACTCATCAACATCCCAAGAATTTGTTGCGAATAGTGATATTGTTAGGGAAAAATATGTT
TTTGAAAGACAGAAAAGGTCAAGCTTTTACATGACGAAGGCTGACGATGTTGTAAATAAT
AAAACGAAAGAAATTATTCCAATCCTCAGTGAGGATGAAACAACAGACGATTTTGAGATA
GATCCTGTAGAAGGTGAATTTCATAAACCAGTGACGATTGTGAAAAATGCAACACTGGAA
GCCATGTGCGGTTCTATATCATTAAAAGTACGAGATGTACAGTGCTTTCCAAAACCTGAC
GCTCTCAATCCATGTGAGGATGTGATGGGCAGCAGTTGGCTGAGGGCATCTGTATGGATA
GTTGTGTCATTAGCAGTCATTGGAAATGTAGCAGTATTAGTAGTTTTATTATCAAATCGA
TCAGAATTTACTGTTCCAAAATTCCTAATGTGTAATTTAGCATTAGCAGATTTTTGCATG
GGAATTTATTTACTTCTTATTGCATCAATTGATCTACATTCAATGGGAGAATATTTTAAT
CTTGCATTCGATTGGCAATATGGTATTGGCTGCAAGACAGCTGGATGGCTAACTGTATTT
GCAGGTCATCTTTCTATTTTCACACTCACAATTATTACGGTTGAACGATGGTTTGCCATA
ACACATGCAATCTATTTAAATAAACGTTTAAAGCATCGCACTGCAGTTTATATCATGATA
TGTGGATGGCTTTATTCTATAATAATGGCTATTATGCCACTTTATGGAATCTCAAATTAT
TCGTCTACTAGCATTTGTCTTCCTATGGAAGCGAAAGATACAGCCGACGTGATTTATTTG
ATAACAGTATTGGCCGTGAATGGTTTGGGATTTTTCATTGTAGTCATATGCTACGCACAA
ATATATTTCTCTTTGGGAAAAGAGACTAGGCAGCGTGGAATGGGAAGTGGTGGGCGTTCA
GAAATGACTGTTGCAAAGAAAATGGCACTTTTGGTATTTACGAATTTCGCATGTTGGGCA
CCGATTGCATTTTTTGGTCTCACTGCGCTTGCTGGCTATCCTTTGATTAATGTAACCAAA
TCTAAAATACTCTTGGTGTTTTTTTATCCGATTAATTCTTGTGCAAATCCATATCTATAT
GCGATTCTTACGTCACAATATCGCCGCGATTTATTCCAACTATTATCGAAATTTGGCATG
TGCACACAACGTGCACAAAAATATAGAATGAACTATAGTAACAATCCAACACATACAATT
CCATTAAACATGCTATCAAGCATTCGTACTTCCAACTCAATTAATTTTCAATATCGTCGC
ACTAATAGCAACATAAAATCAAATGCTGAGCAACTACTAATTACAGACAATGCAACCCTA
ATGCATAGCGACGTTCATGTAAATGGAAAAAATTTGTGTGATGATTCTTAA
>g2763.t1 Gene=g2763 Length=856
MKIVKNTLKYKWKILFLLCNWINFFITSSFYFKFAECEVSSSTYLDRIKFMNENSTFLYS
LINTNVTKTPLTNFTANDEISEPWRCLCSNGLEDQDAKNGEIECHCEGLPLKNIPQNLFN
FTRLSVVNTNLKQLRESELRKYAAFIKDISLTNLNEFEKIDSDAFKNTRQLRALEISHAP
KLKSIDKETFQYVTYSFKILRIVHSGLEQIPDVSFLQINTKILLQLDFEGNQITKIPENS
IQIRTEQLILDNNKLTKVEKAAFNGSEIGKLSLKGNTKLRFLHVRAFEGIKNIRELDLSS
TFIESLPTLGLNKLETLRIQNTRSLKHIPSVFELMNLEKAWLTHSFHCCAFKFPQRHDPT
RHEKHLQLIESFKNECKEKGYSSTSQEFVANSDIVREKYVFERQKRSSFYMTKADDVVNN
KTKEIIPILSEDETTDDFEIDPVEGEFHKPVTIVKNATLEAMCGSISLKVRDVQCFPKPD
ALNPCEDVMGSSWLRASVWIVVSLAVIGNVAVLVVLLSNRSEFTVPKFLMCNLALADFCM
GIYLLLIASIDLHSMGEYFNLAFDWQYGIGCKTAGWLTVFAGHLSIFTLTIITVERWFAI
THAIYLNKRLKHRTAVYIMICGWLYSIIMAIMPLYGISNYSSTSICLPMEAKDTADVIYL
ITVLAVNGLGFFIVVICYAQIYFSLGKETRQRGMGSGGRSEMTVAKKMALLVFTNFACWA
PIAFFGLTALAGYPLINVTKSKILLVFFYPINSCANPYLYAILTSQYRRDLFQLLSKFGM
CTQRAQKYRMNYSNNPTHTIPLNMLSSIRTSNSINFQYRRTNSNIKSNAEQLLITDNATL
MHSDVHVNGKNLCDDS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 40 | g2763.t1 | CDD | cd15136 | 7tmA_Glyco_hormone_R | 492 | 771 | 2.52629E-160 |
| 22 | g2763.t1 | Gene3D | G3DSA:1.20.1070.10 | - | 492 | 778 | 1.6E-45 |
| 3 | g2763.t1 | PANTHER | PTHR24372:SF74 | LP13728P | 188 | 832 | 1.5E-196 |
| 4 | g2763.t1 | PANTHER | PTHR24372 | GLYCOPROTEIN HORMONE RECEPTOR | 188 | 832 | 1.5E-196 |
| 17 | g2763.t1 | PRINTS | PR00373 | Glycoprotein hormone receptor signature | 482 | 499 | 9.6E-49 |
| 11 | g2763.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 493 | 517 | 7.6E-23 |
| 16 | g2763.t1 | PRINTS | PR00373 | Glycoprotein hormone receptor signature | 518 | 531 | 9.6E-49 |
| 8 | g2763.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 526 | 547 | 7.6E-23 |
| 18 | g2763.t1 | PRINTS | PR00373 | Glycoprotein hormone receptor signature | 558 | 571 | 9.6E-49 |
| 14 | g2763.t1 | PRINTS | PR00373 | Glycoprotein hormone receptor signature | 571 | 585 | 9.6E-49 |
| 9 | g2763.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 578 | 600 | 7.6E-23 |
| 7 | g2763.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 614 | 635 | 7.6E-23 |
| 13 | g2763.t1 | PRINTS | PR00373 | Glycoprotein hormone receptor signature | 632 | 643 | 9.6E-49 |
| 5 | g2763.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 659 | 682 | 7.6E-23 |
| 15 | g2763.t1 | PRINTS | PR00373 | Glycoprotein hormone receptor signature | 700 | 718 | 9.6E-49 |
| 10 | g2763.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 704 | 728 | 7.6E-23 |
| 12 | g2763.t1 | PRINTS | PR00373 | Glycoprotein hormone receptor signature | 734 | 750 | 9.6E-49 |
| 6 | g2763.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 742 | 768 | 7.6E-23 |
| 19 | g2763.t1 | PRINTS | PR00373 | Glycoprotein hormone receptor signature | 763 | 782 | 9.6E-49 |
| 1 | g2763.t1 | Pfam | PF13855 | Leucine rich repeat | 246 | 301 | 5.4E-9 |
| 2 | g2763.t1 | Pfam | PF00001 | 7 transmembrane receptor (rhodopsin family) | 508 | 760 | 9.7E-36 |
| 23 | g2763.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 11 | - |
| 39 | g2763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 32 | - |
| 30 | g2763.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 33 | 492 | - |
| 36 | g2763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 493 | 517 | - |
| 27 | g2763.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 518 | 528 | - |
| 38 | g2763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 529 | 550 | - |
| 29 | g2763.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 551 | 573 | - |
| 34 | g2763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 574 | 594 | - |
| 24 | g2763.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 595 | 614 | - |
| 32 | g2763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 615 | 637 | - |
| 28 | g2763.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 638 | 656 | - |
| 37 | g2763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 657 | 683 | - |
| 26 | g2763.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 684 | 708 | - |
| 33 | g2763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 709 | 731 | - |
| 31 | g2763.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 732 | 742 | - |
| 35 | g2763.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 743 | 763 | - |
| 25 | g2763.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 764 | 856 | - |
| 49 | g2763.t1 | ProSitePatterns | PS00237 | G-protein coupled receptors family 1 signature. | 584 | 600 | - |
| 50 | g2763.t1 | ProSiteProfiles | PS50262 | G-protein coupled receptors family 1 profile. | 508 | 760 | 31.485 |
| 21 | g2763.t1 | SUPERFAMILY | SSF52058 | L domain-like | 105 | 354 | 1.36E-22 |
| 20 | g2763.t1 | SUPERFAMILY | SSF81321 | Family A G protein-coupled receptor-like | 482 | 784 | 8.79E-53 |
| 46 | g2763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 31 | - |
| 44 | g2763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 496 | 518 | - |
| 43 | g2763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 531 | 553 | - |
| 47 | g2763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 573 | 595 | - |
| 41 | g2763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 615 | 637 | - |
| 45 | g2763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 657 | 679 | - |
| 48 | g2763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 711 | 733 | - |
| 42 | g2763.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 743 | 762 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007186 | G protein-coupled receptor signaling pathway | BP |
| GO:0005515 | protein binding | MF |
| GO:0016500 | protein-hormone receptor activity | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0004930 | G protein-coupled receptor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K04249 (thyrotropin receptor)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
