Gene loci information

Transcript annotation

  • This transcript has been annotated as Dihydrolipoyl dehydrogenase, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2842 g2842.t2 TSS g2842.t2 20511705 20511705
chr_3 g2842 g2842.t2 isoform g2842.t2 20511806 20512728
chr_3 g2842 g2842.t2 exon g2842.t2.exon1 20511806 20511847
chr_3 g2842 g2842.t2 cds g2842.t2.CDS1 20511806 20511847
chr_3 g2842 g2842.t2 exon g2842.t2.exon2 20511981 20512071
chr_3 g2842 g2842.t2 cds g2842.t2.CDS2 20511981 20512071
chr_3 g2842 g2842.t2 exon g2842.t2.exon3 20512136 20512728
chr_3 g2842 g2842.t2 cds g2842.t2.CDS3 20512136 20512728
chr_3 g2842 g2842.t2 TTS g2842.t2 NA NA

Sequences

>g2842.t2 Gene=g2842 Length=726
ATGCAAGCAAACATTAGACAAGTTGCTTCATTATTTTCAAAGCTAAATATCAATACAATC
CATCGTTCAGCCGCTGTACTTCAATGTCGTGCTTATTCGACAACGCATGATGCCGATTTA
GTTGTTATTGGAGGTGGTCCAGGAGGATATGTCGCAGCAATTAAGGGCGCTCAAGTTGGA
CTTAACACAGTTTGTATTGAAAAGAATGATACACTCGGTGGCACTTGTCTCAATGTTGGA
TGCATTCCTTCAAAAGCTCTTCTCAACAACTCGCATTATTATCATATGGCACACTCTGGT
GACCTCAATAATCGCGGTATCACTGTTGGAAATGTGTCATTAGACTTGGAGAAAATGATG
GGTCAAAAGTCAAACGCCGTAAAGTCACTGACCGGAGGAATTGCACAGTTATTTAAAAAG
AACAAAGTTACACATCTCAACGGTTGGGGACAAATCACAGGTCCAAATCAAGTTCAAGCA
AAAATGAAGGATGGTTCAGTCGAGACAGTAAATACAAAATACATGATCATTGCTAGCGGT
TCTGAAGTCACACCTTTCCCAGGAGTAACAATTGATGAGGAAGTTATTGTGTCAAGTACT
GGTGCTTTGAGTTTAAAACAAGTTCCTAAGAAAATGGTCGTAATTGGAGCTGGTGTTATT
GGTCTCGAATTAGGATCAGTTTGGTCACGTCTTGGCGCAGAAGTTATTGCCGTTGAATTC
TTAAAT

>g2842.t2 Gene=g2842 Length=242
MQANIRQVASLFSKLNINTIHRSAAVLQCRAYSTTHDADLVVIGGGPGGYVAAIKGAQVG
LNTVCIEKNDTLGGTCLNVGCIPSKALLNNSHYYHMAHSGDLNNRGITVGNVSLDLEKMM
GQKSNAVKSLTGGIAQLFKKNKVTHLNGWGQITGPNQVQAKMKDGSVETVNTKYMIIASG
SEVTPFPGVTIDEEVIVSSTGALSLKQVPKKMVVIGAGVIGLELGSVWSRLGAEVIAVEF
LN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
14 g2842.t2 Gene3D G3DSA:3.50.50.60 - 39 183 1.4E-75
13 g2842.t2 Gene3D G3DSA:3.50.50.60 - 184 240 1.4E-75
2 g2842.t2 PANTHER PTHR22912:SF151 DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL 34 241 1.4E-91
3 g2842.t2 PANTHER PTHR22912 DISULFIDE OXIDOREDUCTASE 34 241 1.4E-91
8 g2842.t2 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 61 2.5E-39
6 g2842.t2 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 40 59 7.0E-20
9 g2842.t2 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 72 87 2.5E-39
5 g2842.t2 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 7.0E-20
7 g2842.t2 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 184 2.5E-39
4 g2842.t2 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 229 7.0E-20
10 g2842.t2 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 211 236 2.5E-39
1 g2842.t2 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 39 239 3.8E-34
12 g2842.t2 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 73 83 -
11 g2842.t2 SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain 36 241 4.75E-47

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed