Gene loci information

Transcript annotation

  • This transcript has been annotated as Dihydrolipoyl dehydrogenase, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2842 g2842.t7 TSS g2842.t7 20511705 20511705
chr_3 g2842 g2842.t7 isoform g2842.t7 20512170 20513272
chr_3 g2842 g2842.t7 exon g2842.t7.exon1 20512170 20513272
chr_3 g2842 g2842.t7 cds g2842.t7.CDS1 20512288 20513271
chr_3 g2842 g2842.t7 TTS g2842.t7 20513825 20513825

Sequences

>g2842.t7 Gene=g2842 Length=1103
CGCTCAAGTTGGACTTAACACAGTTTGTATTGAAAAGAATGATACACTCGGTGGCACTTG
TCTCAATGTTGGATGCATTCCTTCAAAAGCTCTTCTCAACAACTCGCATTATTATCATAT
GGCACACTCTGGTGACCTCAATAATCGCGGTATCACTGTTGGAAATGTGTCATTAGACTT
GGAGAAAATGATGGGTCAAAAGTCAAACGCCGTAAAGTCACTGACCGGAGGAATTGCACA
GTTATTTAAAAAGAACAAAGTTACACATCTCAACGGTTGGGGACAAATCACAGGTCCAAA
TCAAGTTCAAGCAAAAATGAAGGATGGTTCAGTCGAGACAGTAAATACAAAATACATGAT
CATTGCTAGCGGTTCTGAAGTCACACCTTTCCCAGGAGTAACAATTGATGAGGAAGTTAT
TGTGTCAAGTACTGGTGCTTTGAGTTTAAAACAAGTTCCTAAGAAAATGGTCGTAATTGG
AGCTGGTGTTATTGGTCTCGAATTAGGATCAGTTTGGTCACGTCTTGGCGCAGAAGTTAT
TGCCGTTGAATTCTTAAATAGCATTGGAGGAGTTGGAATTGATGGTGAAGTATCAAAAAC
CTTCCAAAAAGTTCTCACAAAACAAGGAATGCAATTTAGACTCGGTACAAAAGTGACTGG
TGCACAACGTACTGGCAATGGAGCTGTAGTCTCAGTCGAATCAGTAAAAGACGGTTCAAA
GGAAGATATTGAATGTGATGTTCTTCTTGTTTGTATTGGTCGTCGTCCATTTACAGAAGG
ATTAGGTCTCGAAAATGTTGGAATTGCAACTGACGATCGTGGTAGAATCCCTGTTAATGC
AATGCTTCAAACTATTGTACCTAATATTCATGCAATCGGCGATGTAATTCATGGACCTAT
GTTGGCGCACAAAGCTGAAGATGAGGGAATAATCTGTGTTGAAGGAATTATGGGTGGTCA
CGTACATCTTGATTATAATTGTGTGCCCTCAGTTGTATATACACATCCAGAAGTTGCATG
GGTTGGAAAATCTGAAGAGGATCTGAAAAAAGAAGGAGTCGAATACAAAGTTGGCAAATT
TCCATACATGGCAAACTCTCGTG

>g2842.t7 Gene=g2842 Length=328
MAHSGDLNNRGITVGNVSLDLEKMMGQKSNAVKSLTGGIAQLFKKNKVTHLNGWGQITGP
NQVQAKMKDGSVETVNTKYMIIASGSEVTPFPGVTIDEEVIVSSTGALSLKQVPKKMVVI
GAGVIGLELGSVWSRLGAEVIAVEFLNSIGGVGIDGEVSKTFQKVLTKQGMQFRLGTKVT
GAQRTGNGAVVSVESVKDGSKEDIECDVLLVCIGRRPFTEGLGLENVGIATDDRGRIPVN
AMLQTIVPNIHAIGDVIHGPMLAHKAEDEGIICVEGIMGGHVHLDYNCVPSVVYTHPEVA
WVGKSEEDLKKEGVEYKVGKFPYMANSR

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g2842.t7 Gene3D G3DSA:3.50.50.60 - 2 271 0
16 g2842.t7 Gene3D G3DSA:3.50.50.60 - 89 213 0
17 g2842.t7 Gene3D G3DSA:3.30.390.30 - 286 328 0
3 g2842.t7 PANTHER PTHR22912:SF151 DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL 2 328 0
4 g2842.t7 PANTHER PTHR22912 DISULFIDE OXIDOREDUCTASE 2 328 0
7 g2842.t7 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 77 95 0
11 g2842.t7 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 80 89 0
6 g2842.t7 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 0
13 g2842.t7 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 116 141 0
8 g2842.t7 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 206 222 0
9 g2842.t7 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 207 221 0
5 g2842.t7 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 257 0
10 g2842.t7 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 250 257 0
12 g2842.t7 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 285 306 0
1 g2842.t7 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 25 270 0
2 g2842.t7 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 289 328 0
14 g2842.t7 SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain 17 307 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0050660 flavin adenine dinucleotide binding MF
GO:0055114 NA NA
GO:0045454 cell redox homeostasis BP
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values