General information for g2924.t12
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Inositol-3-phosphate synthase.
Parent gene
- The parent gene g2924 is located on chr_3: 21259921..21267778 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g2924 | g2924.t12 | TTS | g2924.t12 | 21259729 | 21259729 |
| chr_3 | g2924 | g2924.t12 | isoform | g2924.t12 | 21259921 | 21267778 |
| chr_3 | g2924 | g2924.t12 | exon | g2924.t12.exon1 | 21259921 | 21261459 |
| chr_3 | g2924 | g2924.t12 | cds | g2924.t12.CDS1 | 21259921 | 21261396 |
| chr_3 | g2924 | g2924.t12 | exon | g2924.t12.exon2 | 21267703 | 21267778 |
| chr_3 | g2924 | g2924.t12 | TSS | g2924.t12 | 21267855 | 21267855 |
Sequences
>g2924.t12 Gene=g2924 Length=1615
GAGATCCGAATTACTTCGTTCTCCAATAATTATGTCCTTTATATTTTTTATCAAATCCAT
CAGGAGATAGCTTAAGGTTCATCCGATTACGAAGAGAATTGATATACGAACGGAGCGAAA
TGTACCAAAGCTAGGTCTGATGTTAGTGGGTATGGGTGGAAATAATGGATCAACTCTCAT
TGCTGCTCTTGAAGCTAATCGTCAAAAATTGACATGGCGCACAAAAGAAGGTCTAAAAGA
AGCTAATTGGTTTGGATCGATCACTCAATCAGCAACAGTTTTACTTGGTTCAGACTTTGA
GGGCAAAGATGTTTATGCACCAATGAATGAATTTGTTCCAATGGTCAATCCTGAAAATAT
TATTGTTGATGGTTGGGATATCAGTTCAATGAATATTGGTGATGCTATGAGGCGGGCAAA
AGTATTAGATGTCAACTTGCAAGATCAACTTTATAAAAAACTCTCACAAATTTCTCCTCG
ACCATCGATTTATTTTCCAGACTTTATTGCTGCTAATCAATTAGATCGTGCTGACAACTT
GATTTTAGGCACCAAGTACGAACAGTTTATGAAAATTCGCGATGACATTCGTGAGTTTAA
AAAGACCAATGAAGTTGATAAGGTTGTTGTTTTATGGACAGCTAATACTGAACGTTTTTG
TGATGTACGTGAGGGTTTGAATTCTACTATGCAAGAATTAGAGACGTCATTGAAAAATAA
TGAGAGCGAAATCTCACCATCAACTATTTTTGCTATGGCTGCAATTTTGGAAGGATGCAT
TTACATTAATGGTTCACCGCAAAATACTTTTGTGCCTGGAGTAATCGAAATGGCTGAAAA
ATATGGAGCTTTCATTGCTGGTGATGATTTTAAATCAGGACAAACAAAATTAAAATCAGT
ACTTGTTGATTTTCTTGTTGGAGCCGGTATCAAACCTGTCTCTATTGTCAGCTACAATCA
TTTGGGCAATAATGACGGAAAGAATCTCAATTCACCATCACAATTTCGCTCAAAAGAAAT
TTCAAAGAGTAATGTTGTGGATGATATGGTTGAAAGCAATGAAATTTTATACAAGCCAAA
GGAGCATCCAGATCATTGCGTTGTTATCAAGTATGTGCCATATGTTGGTGATAGCAAGCG
CGCAATGGATGAATACACGAGCGAAATAATGATGGGTGGACATAACACACTTGTAATTCA
TAACACATGCGAAGATTCACTCTTGGCAACTCCATTAATTCTTGATCTCGTTATTTTGGG
CGAATTGTGTTCACGAATTAAAATCAGAGATCATACCAAATCAGATGCCAAATTTGAGTC
GTGCAAATCAGTTCTTTCTCTTCTATCATATTTATGTAAAGCACCACTTGTACCAAAAGG
AAGTCAAGTTGTTAATTCACTATTTCGTCAACGTGCTGCTATTGAAAACATTTTGAGAGC
TTGTGTCGGCTTGTCTCCAAACAGTCATATGGCACTTGAACATAGATTTGATTTTTCATC
CATTCCAATCAATCAAAAAACTGTCGAATCAAGTTTAAAATTAAATGGCTATACAAATGG
ATTTCATGAAGAAAAAACATCAAATGGAATTGTTGTCGAGAATGGCATACATTAA
>g2924.t12 Gene=g2924 Length=491
MLVGMGGNNGSTLIAALEANRQKLTWRTKEGLKEANWFGSITQSATVLLGSDFEGKDVYA
PMNEFVPMVNPENIIVDGWDISSMNIGDAMRRAKVLDVNLQDQLYKKLSQISPRPSIYFP
DFIAANQLDRADNLILGTKYEQFMKIRDDIREFKKTNEVDKVVVLWTANTERFCDVREGL
NSTMQELETSLKNNESEISPSTIFAMAAILEGCIYINGSPQNTFVPGVIEMAEKYGAFIA
GDDFKSGQTKLKSVLVDFLVGAGIKPVSIVSYNHLGNNDGKNLNSPSQFRSKEISKSNVV
DDMVESNEILYKPKEHPDHCVVIKYVPYVGDSKRAMDEYTSEIMMGGHNTLVIHNTCEDS
LLATPLILDLVILGELCSRIKIRDHTKSDAKFESCKSVLSLLSYLCKAPLVPKGSQVVNS
LFRQRAAIENILRACVGLSPNSHMALEHRFDFSSIPINQKTVESSLKLNGYTNGFHEEKT
SNGIVVENGIH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g2924.t12 | Coils | Coil | Coil | 177 | 197 | - |
| 7 | g2924.t12 | Gene3D | G3DSA:3.40.50.720 | - | 1 | 447 | 2.0E-232 |
| 8 | g2924.t12 | Gene3D | G3DSA:3.30.360.10 | Dihydrodipicolinate Reductase; domain 2 | 253 | 365 | 2.0E-232 |
| 3 | g2924.t12 | PANTHER | PTHR11510:SF5 | INOSITOL-3-PHOSPHATE SYNTHASE 1 | 1 | 449 | 7.1E-237 |
| 4 | g2924.t12 | PANTHER | PTHR11510 | MYO-INOSITOL-1 PHOSPHATE SYNTHASE | 1 | 449 | 7.1E-237 |
| 10 | g2924.t12 | PIRSF | PIRSF015578 | Myoinositol-ppht_synth | 1 | 450 | 3.2E-184 |
| 2 | g2924.t12 | Pfam | PF07994 | Myo-inositol-1-phosphate synthase | 1 | 433 | 1.9E-137 |
| 1 | g2924.t12 | Pfam | PF01658 | Myo-inositol-1-phosphate synthase | 247 | 360 | 5.9E-44 |
| 5 | g2924.t12 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 1 | 449 | 6.62E-140 |
| 6 | g2924.t12 | SUPERFAMILY | SSF55347 | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 246 | 359 | 1.57E-41 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008654 | phospholipid biosynthetic process | BP |
| GO:0006021 | inositol biosynthetic process | BP |
| GO:0004512 | inositol-3-phosphate synthase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01858 (myo-inositol-1-phosphate synthase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
