Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Hexokinase type 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2925 g2925.t23 TSS g2925.t23 21267310 21267310
chr_3 g2925 g2925.t23 isoform g2925.t23 21267719 21271507
chr_3 g2925 g2925.t23 exon g2925.t23.exon1 21267719 21267778
chr_3 g2925 g2925.t23 cds g2925.t23.CDS1 21267719 21267778
chr_3 g2925 g2925.t23 exon g2925.t23.exon2 21271023 21271185
chr_3 g2925 g2925.t23 cds g2925.t23.CDS2 21271023 21271185
chr_3 g2925 g2925.t23 exon g2925.t23.exon3 21271251 21271435
chr_3 g2925 g2925.t23 cds g2925.t23.CDS3 21271251 21271435
chr_3 g2925 g2925.t23 exon g2925.t23.exon4 21271497 21271507
chr_3 g2925 g2925.t23 cds g2925.t23.CDS4 21271497 21271505
chr_3 g2925 g2925.t23 TTS g2925.t23 NA NA

Sequences

>g2925.t23 Gene=g2925 Length=419
ATGGATTTGATAAAAAATATAAAGGACATAATTATTGGAGAACGAAGTAATTCGGATCTC
ATCAAGGAAGCCTGTCAGGAGTTGATATTGGATGACAAAACAATGAGAGAAATCATGAAG
AGATTTCTTCATGAAATTCAACTTGGGTTAAAGAAAGAGACACATCCAGCAGCTGACATT
AAGTGCTTCATAACTTACGTTCAAGATTTGCCAAATGGAAAAGAAAAAGGCAGATTCCTT
GCATTGGATTTAGGTGGTACGAATTTCCGTGTCCTTCTTATTCATCTCAAAGGTGACAGT
GAGTTCGAAATGCAATCAAAGATTTACGCCATCCCACAAAGTATTATGATTGGTTCGGGA
ACACAATTGTTTGACCATATTGCTGAATGTCTTGCAAATTTCATCAAGGAACATAAACT

>g2925.t23 Gene=g2925 Length=139
MDLIKNIKDIIIGERSNSDLIKEACQELILDDKTMREIMKRFLHEIQLGLKKETHPAADI
KCFITYVQDLPNGKEKGRFLALDLGGTNFRVLLIHLKGDSEFEMQSKIYAIPQSIMIGSG
TQLFDHIAECLANFIKEHK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g2925.t23 Gene3D G3DSA:3.40.367.20 - 26 64 0.000
5 g2925.t23 Gene3D G3DSA:3.30.420.40 - 65 139 0.000
2 g2925.t23 PANTHER PTHR19443:SF4 HEXOKINASE-2 21 138 0.000
3 g2925.t23 PANTHER PTHR19443 HEXOKINASE 21 138 0.000
1 g2925.t23 Pfam PF00349 Hexokinase 21 138 0.000
7 g2925.t23 ProSiteProfiles PS51748 Hexokinase domain profile. 15 139 13.584
4 g2925.t23 SUPERFAMILY SSF53067 Actin-like ATPase domain 18 138 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0001678 cellular glucose homeostasis BP
GO:0005524 ATP binding MF
GO:0016773 phosphotransferase activity, alcohol group as acceptor MF
GO:0005975 carbohydrate metabolic process BP
GO:0005536 glucose binding MF
GO:0004396 hexokinase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed