Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Hexokinase type 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2925 g2925.t39 isoform g2925.t39 21273203 21274145
chr_3 g2925 g2925.t39 exon g2925.t39.exon1 21273203 21273542
chr_3 g2925 g2925.t39 cds g2925.t39.CDS1 21273213 21273542
chr_3 g2925 g2925.t39 exon g2925.t39.exon2 21273600 21274145
chr_3 g2925 g2925.t39 cds g2925.t39.CDS2 21273600 21273776
chr_3 g2925 g2925.t39 TTS g2925.t39 21274517 21274517
chr_3 g2925 g2925.t39 TSS g2925.t39 NA NA

Sequences

>g2925.t39 Gene=g2925 Length=886
AGTTGAAAAGATGATTTCGGGAATGTATATGGGTGAATTAGTGAGACTTGCACTTGTTAG
ATTCACAAAAGAAGGACTTTTGTTTGGTGGACAAGGATCTGATTTACTCTTCAAACGTTA
CCAATTTTTCACAAAATACGTGTCTGAAATTGAGAGCGATAAGCCTGGAACTTTCTTTAA
TTGTTATGATGTGCTTGAGGAAATTGGAATTTTCCATGCCACTGATGAGGACTGTGCAAA
TGTGAGATATATTTGCGAGTGCATTTCAAGTCGTGCTGCTCATTTATCATCAGCTGGTAT
TGCCACGCTTATAAACAAAATGAATGATCCAAGTGTTACTGTCGGTGTTGATGGATCTGT
CTATCGTTTCCATCCTAAATTCCATGATTTAATGATGGTAAAAATTCGTGAACTTGTTCA
TGATCACATTCAATTTGACATCATGCTGTCTGAAGATGGGTCTGGAAGAGGAGCTGCTCT
TGTTGCTGCTGTTGCTTCACGTGATGCACATGAATAAGACTCTTATGTGTAATGAGAATC
TTTAAACAAAATAACTCTCGAGACGAACAATTCTGAAACGGGAGTCTAAATCATTTTAAT
TTTTAGTTGTAAGAATCAAAAAGTGTTTAAATTTTATTGTTTTGTATTAGTTCTTAGTAT
GTAGTCGTATGCAATGTGGAGTGCATGGATATTTTTGTAAAAAATCTCTTGTGAATCGCT
CGATTTTGAGGTTGATGCAAAAAAAATAAATTTTTTATTATTTATTATAATTTTTCTTGT
CGTACTCTTCATTTCAAAACAAGATCATACATATAGTTCCAACTGATAAAAAAATATTAA
AATAACCTTTTAAAGAAGCAATAACTTTAACATCCAGCCGATTACA

>g2925.t39 Gene=g2925 Length=168
MISGMYMGELVRLALVRFTKEGLLFGGQGSDLLFKRYQFFTKYVSEIESDKPGTFFNCYD
VLEEIGIFHATDEDCANVRYICECISSRAAHLSSAGIATLINKMNDPSVTVGVDGSVYRF
HPKFHDLMMVKIRELVHDHIQFDIMLSEDGSGRGAALVAAVASRDAHE

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g2925.t39 Gene3D G3DSA:3.40.367.20 - 1 168 0.000
2 g2925.t39 PANTHER PTHR19443:SF33 PHOSPHOTRANSFERASE 1 166 0.000
3 g2925.t39 PANTHER PTHR19443 HEXOKINASE 1 166 0.000
1 g2925.t39 Pfam PF03727 Hexokinase 1 161 0.000
6 g2925.t39 ProSiteProfiles PS51748 Hexokinase domain profile. 1 160 16.837
4 g2925.t39 SUPERFAMILY SSF53067 Actin-like ATPase domain 1 165 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0001678 cellular glucose homeostasis BP
GO:0005524 ATP binding MF
GO:0016773 phosphotransferase activity, alcohol group as acceptor MF
GO:0005975 carbohydrate metabolic process BP
GO:0005536 glucose binding MF
GO:0004396 hexokinase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values