Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Hexokinase type 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g2925 g2925.t9 TSS g2925.t9 21264718 21264718
chr_3 g2925 g2925.t9 isoform g2925.t9 21264957 21272788
chr_3 g2925 g2925.t9 exon g2925.t9.exon1 21264957 21264995
chr_3 g2925 g2925.t9 cds g2925.t9.CDS1 21264957 21264995
chr_3 g2925 g2925.t9 exon g2925.t9.exon2 21271023 21271185
chr_3 g2925 g2925.t9 cds g2925.t9.CDS2 21271023 21271185
chr_3 g2925 g2925.t9 exon g2925.t9.exon3 21271251 21271435
chr_3 g2925 g2925.t9 cds g2925.t9.CDS3 21271251 21271435
chr_3 g2925 g2925.t9 exon g2925.t9.exon4 21271497 21271674
chr_3 g2925 g2925.t9 cds g2925.t9.CDS4 21271497 21271674
chr_3 g2925 g2925.t9 exon g2925.t9.exon5 21272698 21272788
chr_3 g2925 g2925.t9 cds g2925.t9.CDS5 21272698 21272711
chr_3 g2925 g2925.t9 TTS g2925.t9 NA NA

Sequences

>g2925.t9 Gene=g2925 Length=656
ATGTCCAAAGGTGTAGTAATGACTAAACCAACAAAAGAGATCAAGGAAGCCTGTCAGGAG
TTGATATTGGATGACAAAACAATGAGAGAAATCATGAAGAGATTTCTTCATGAAATTCAA
CTTGGGTTAAAGAAAGAGACACATCCAGCAGCTGACATTAAGTGCTTCATAACTTACGTT
CAAGATTTGCCAAATGGAAAAGAAAAAGGCAGATTCCTTGCATTGGATTTAGGTGGTACG
AATTTCCGTGTCCTTCTTATTCATCTCAAAGGTGACAGTGAGTTCGAAATGCAATCAAAG
ATTTACGCCATCCCACAAAGTATTATGATTGGTTCGGGAACACAATTGTTTGACCATATT
GCTGAATGTCTTGCAAATTTCATCAAGGAACATAAACTTCAAAATGAACGGCTGCCATTA
GGTTTTACTTTCTCCTTCCCTCTTAAACAGTTAGGTTTAACAAAGGGTATTTTAATCAGA
TGGACTAAAGGTTTCAATTGTGAGGGAGTTGTTGATCGTGATGTCGTTGAACTGTTAGAA
GAGGCATTAAAAAGACGTGGAGTGAGATGTTTCTATTGAAATTTGTGCTATTCTTAATGA
TACAACTGGAACTCTTATGTCATGTGCCTGGAAAAATCACAACTGTAAAATCGGAG

>g2925.t9 Gene=g2925 Length=192
MSKGVVMTKPTKEIKEACQELILDDKTMREIMKRFLHEIQLGLKKETHPAADIKCFITYV
QDLPNGKEKGRFLALDLGGTNFRVLLIHLKGDSEFEMQSKIYAIPQSIMIGSGTQLFDHI
AECLANFIKEHKLQNERLPLGFTFSFPLKQLGLTKGILIRWTKGFNCEGVVDRDVVELLE
EALKRRGVRCFY

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g2925.t9 CDD cd00012 NBD_sugar-kinase_HSP70_actin 73 161 4.41381E-6
8 g2925.t9 Gene3D G3DSA:3.40.367.20 - 19 57 1.3E-68
7 g2925.t9 Gene3D G3DSA:3.30.420.40 - 58 187 1.3E-68
2 g2925.t9 PANTHER PTHR19443:SF4 HEXOKINASE-2 11 187 3.2E-69
3 g2925.t9 PANTHER PTHR19443 HEXOKINASE 11 187 3.2E-69
5 g2925.t9 PRINTS PR00475 Hexokinase family signature 73 89 4.9E-20
4 g2925.t9 PRINTS PR00475 Hexokinase family signature 140 165 4.9E-20
1 g2925.t9 Pfam PF00349 Hexokinase 14 188 1.3E-62
10 g2925.t9 ProSitePatterns PS00378 Hexokinase domain signature. 140 165 -
11 g2925.t9 ProSiteProfiles PS51748 Hexokinase domain profile. 8 192 22.118
6 g2925.t9 SUPERFAMILY SSF53067 Actin-like ATPase domain 6 187 5.3E-68

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0001678 cellular glucose homeostasis BP
GO:0005524 ATP binding MF
GO:0016773 phosphotransferase activity, alcohol group as acceptor MF
GO:0006096 glycolytic process BP
GO:0005975 carbohydrate metabolic process BP
GO:0005536 glucose binding MF
GO:0004396 hexokinase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed