General information for g3270.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Inosine-5’-monophosphate dehydrogenase.
Parent gene
- The parent gene g3270 is located on chr_3: 24105687..24107455 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3270 | g3270.t5 | isoform | g3270.t5 | 24105687 | 24107455 |
| chr_3 | g3270 | g3270.t5 | exon | g3270.t5.exon1 | 24105687 | 24107455 |
| chr_3 | g3270 | g3270.t5 | cds | g3270.t5.CDS1 | 24105810 | 24106832 |
| chr_3 | g3270 | g3270.t5 | TTS | g3270.t5 | 24107451 | 24107451 |
| chr_3 | g3270 | g3270.t5 | TSS | g3270.t5 | NA | NA |
Sequences
>g3270.t5 Gene=g3270 Length=1769
AATGGCTTCACTGGCTATCCCATCACTGAAAATGGCAAACTTGGTGGAAAACTTGTCGGC
ATAGTAACATCGCGTGACATTGATTTTCGTGAAAAAGATATTGATTTGAAACTTGAGGAT
GTGATGACAAAACTCGATGACATGGTCACAGCAAAACAAGGCATCAAATTGCAACAAGCT
AATGAAATTCTCGAAAAAAGCAAAAAGGGAAAATTGCCAATTATAAATCAAAATGGTGAA
CTTGTTGCTCTTATAGCACGAACTGATTTAAAGAAAGCTCGAAGCTATCCAAATGCGTCA
AAAGATAGCAACAAGCAATTGTTAGTTGGTGCAGCAATGGGAACACGTGAAGAAGATAAA
GATCGATTAAAACTTTTAGTTCAAGCCGGTGTTGATGTTGTCATTTTGGACTCATCGCAA
GGAAATTCACGCTATCAAATTGAAATGATTCATTATATAAAATCGACATATCCAGATTTG
CAAGTTGTTGCTGGAAATGTTGTAACACGAGCTCAAGCTAAAAACTTGATCGATGCTGGA
TGCGATGGTTTAAGAGTTGGCATGGGTTGCGGATCGATTTGTATTACACAAGAAGTTATG
GCCTGTGGCTGTCCACAAGCGACTGCTGTTTATCAAGTTGCAAGTTATGCTCGCAAATTT
AATGTACCAATCATTGCTGATGGTGGAATTCAAAATATTGGTCATATTATGAAAGCATTG
AGTCTTGGTGCATCTACTGTTATGATGGGTTCACTTTTGGCTGGAACATCGGAAGCACCA
GGCGACTATTTCTTCTCTGATGGTGTTCGTTTGAAGAAATATCGTGGAATGGGCAGCTTA
GAAGCAATGGAAAGAAAAGATGCGAAAGGTGCAGCAATGTCACGTTATTATCACAATGAA
ATGGACAAACTTCGAGTTGCACAAGGTGTTTCAGGAAACATTGTCGATAAAGGCTCAGTG
TTACGTTTCTTGCCATATTTAGAGTGCGGACTACAACATAGCTGTCAAGATCTTGGTGCT
CGGTCGCTTACTCACTTGAGTGAAATGATTTATTCAAATGAACTACGATTCATGAAAAGA
ACACATTCAGCACAGGCTGAAGGCAATGTTCACAGCTTGTTCTCATATGAAAAGAGACTT
TTCTAACAACCAACTCAAGAAATGATGAAGTCTACATGTGAGTGAGCAAAGGGACTAAAT
TTTTTTTCCTTAATTTTTTCCCTTATTTTATTATTATCATAAGTGATGAAAAATAGTTTC
ATATGTATTTCTAAATTTCATCTGACTGCAATAAACTTAATTTACAAAAATATTCCAACA
TACAAAATTTACTTAACTTTTCTGTGACAAAAATCAATTAGACTATTTTTACACACAAAC
AATTTGCTTAACGTCGCGGAATGTGACTTTAAAATTTACACAATGAAATTGTATCTAGTG
ATTCCCTTGATGAAAAAATTTAAATTACCTTTTAGTTTTTAATGAAATGAAAAATTGTGA
AAATTTTTGTCTAATCATTATTGATAGAAAATCATGATAAAAAAAAATATGAATGTGTTA
AGAAGAAAGAAAAGAAAATATTTAATGTTGAATTATTGAACTAGTAAGTATATATACTTA
TTAGAAAATAAATTGTAAAACTTACTTACTTACTTTTGATGTTTTCCACTAACTATGTAA
CTTTTAATTTGTATTAGATAAAAGAAAATTATTAAAAGAATTGTAGTGAAAATGAAGAGA
TAAATAAAGTAAAATTATATCAATAGAAA
>g3270.t5 Gene=g3270 Length=340
MTKLDDMVTAKQGIKLQQANEILEKSKKGKLPIINQNGELVALIARTDLKKARSYPNASK
DSNKQLLVGAAMGTREEDKDRLKLLVQAGVDVVILDSSQGNSRYQIEMIHYIKSTYPDLQ
VVAGNVVTRAQAKNLIDAGCDGLRVGMGCGSICITQEVMACGCPQATAVYQVASYARKFN
VPIIADGGIQNIGHIMKALSLGASTVMMGSLLAGTSEAPGDYFFSDGVRLKKYRGMGSLE
AMERKDAKGAAMSRYYHNEMDKLRVAQGVSGNIVDKGSVLRFLPYLECGLQHSCQDLGAR
SLTHLSEMIYSNELRFMKRTHSAQAEGNVHSLFSYEKRLF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g3270.t5 | CDD | cd04601 | CBS_pair_IMPDH | 1 | 51 | 4.23903E-22 |
| 7 | g3270.t5 | CDD | cd00381 | IMPDH | 64 | 308 | 3.06876E-131 |
| 5 | g3270.t5 | Gene3D | G3DSA:3.20.20.70 | Aldolase class I | 4 | 340 | 7.8E-140 |
| 2 | g3270.t5 | PANTHER | PTHR11911:SF129 | INOSINE-5’-MONOPHOSPHATE DEHYDROGENASE 1B | 1 | 340 | 5.2E-174 |
| 3 | g3270.t5 | PANTHER | PTHR11911 | INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED | 1 | 340 | 5.2E-174 |
| 1 | g3270.t5 | Pfam | PF00478 | IMP dehydrogenase / GMP reductase domain | 27 | 330 | 3.2E-103 |
| 8 | g3270.t5 | ProSitePatterns | PS00487 | IMP dehydrogenase / GMP reductase signature. | 143 | 155 | - |
| 11 | g3270.t5 | ProSiteProfiles | PS51371 | CBS domain profile. | 1 | 59 | 11.351 |
| 10 | g3270.t5 | SMART | SM01240 | IMPDH_2 | 2 | 330 | 4.6E-143 |
| 9 | g3270.t5 | SMART | SM00116 | cbs_1 | 6 | 54 | 4.6E-6 |
| 4 | g3270.t5 | SUPERFAMILY | SSF51412 | Inosine monophosphate dehydrogenase (IMPDH) | 17 | 338 | 5.76E-105 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003824 | catalytic activity | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
