Gene loci information

Transcript annotation

  • This transcript has been annotated as Toll-like receptor 6.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3317 g3317.t1 isoform g3317.t1 24592325 24596218
chr_3 g3317 g3317.t1 exon g3317.t1.exon1 24592325 24596218
chr_3 g3317 g3317.t1 cds g3317.t1.CDS1 24592325 24596218
chr_3 g3317 g3317.t1 TSS g3317.t1 NA NA
chr_3 g3317 g3317.t1 TTS g3317.t1 NA NA

Sequences

>g3317.t1 Gene=g3317 Length=3894
ATGAAGCATCGAAGATATTCTTTTATGACTTCGACAGTCATTTATTGCTGTCTTATTCTT
GTACTGAATCACAAAATTTCATCAATAGCACAGTCAACATCGAATGAAGAATGCAGTTAT
GAAACAATCGATGAGTCATTACTGATGACATTATCAAATGATCAAAATATTTCTAATACT
AAGCTCCTATCATGTAGATTTAAGAAACTACCAAAAACCTTCCCCATAGCTTCCGCTAAA
AGTGTAGAAAATTTAAAAATTATTTGTGATAAACTTTTATTTGCCAATGGTGGTGATAGT
GGCAGCAAGTCTTCGAATTTTTTTGATAATTTTGAAAATTTGAAAAATTTATTTCTTGAG
AATTGTGATGGAAATTTTTTGAGAAATTTTAATTCGTTAAAGTCACTAAATGGTCTTACG
ATTCGAAATTATAAAACTTTTTGGGGTCGATATGATGAAGTGATGGATGATTTTGGAACG
TCAAATGATTATGAGCCATTTGATAATTTGCAAAATATTAAGAGTCTAGACATAAGTGAT
AACGGTATTCAAGAACTTCATCGAAATTTCTTTTGTGATTTTCATAAATTAAGTTTCCTC
AATATTTCATCAAATCAAATTTACAATTTGACAAACTTTCAATTTTCTTCGACACCAATA
AAGAATTGTGTCTTTTCTATGTCGTATCTTATATTGACGAACAATCAACTCAATTTCCTT
CCGTTCTCATTCTTCTCAAATTTTGTCAATCTAAAAGTTCTCAGACTCAATCGCAATTCT
ATATCATTCATAGAGAATTTTGTGTTTTCAAATTTAAAGCAATTGGACATGCTCGATTTA
AGTGAGAATAAAATTCAGAGCATTCAACCAGAATTATTTGACAATTTGCAAAATTTACGA
ACACTCAATCTCGAGAAAAATTCAATGAAAATACTTCCACCCGAATTACTTGCTAATTTG
AAAAAGCTCGAGCTATTAAATTTATCATCCAATTTCCTCTCATCGAATTGGATTAATTTC
ATGACCTTCAAGAATTTATTCAACTTGCGACTACTCGATTTATCCTATAATAAGCTCACT
GCGCTTGAAAATTCAGTTTTTGCTGATTTGGCAGCACTCGAAGTACTCGACTTGAAGAAC
AATCTTATTGAGAGCATTGCGATGGATACTTTTGCCAATCTGACATCACTCTCATCGCTC
GTTCTTTCACATAATTTCATCAAAAATGTCAATTTTTCTCTCAACTCGTTGACGAATCTC
AACGTACTATCGCTAGATTTTAATGAAATTTATTCTGTTGAGAAGCATTTAGTCGCGAAT
TCTATGAAACTCGTCGACCTTCATCTCAACAACAATAAATTCTTTCGTGTACCAACTTTT
GTTGAGAATTTTCAATTTCTCAAGTTTCTTGACCTCGGCGAAAATTTTATAAAAAATCTC
TCAGACTTGGAAAATCTTCCAAATCTTAAATATCTTTACGGCTTACGCTTGACCGAGAAT
CAAATTGAAACGCTCGAGAAGAATCATTTTGTTCATTTAAAGAATCTACAGATAGTTAAT
TTATCGAAAAATCGAATTCGTCACATTGATCGTGAGTCATTTGCCGCTAATGAATTCTTA
CAGGCAATTCGACTTGATGGAAATTCAATCAAAAATATTGACTATATGTTCGAGAACCTC
ACACAACTCGTCTTCCTTAATATCTCTGAAAATGCACTTGAAGTGTTTGATTACGAAAAC
TTTCCCAAAAATCTTCAGTTCCTCGATATCTCCAAAAATCAGATCAATGTGATTAAAAAT
CCAAATGAAATATCGCAGAACCTTAAGACACTCAATCTCAATTACAATCATTTAACCGAA
ATTTCTGCTTTTGTGCTACCGCGCAATCTCGAAGATCTCTATCTTCAGTCAAATCTCATT
GAAAAAATTTCTCCATACACGTTCATCAAGAAGTCATTCCTTAAGACTGTCGATTTAAAG
CACAATCGAATTGCACATCTTAACGAAAATGCATTAAGAATTTCATCGACAAAGAGTGAT
GAAAAATTGCCGGAATTTCATCTTGCAGGCAATCCGCTGGTTTGTGATTGTCACTTAAAA
TGGATGTGGCAGGACAATATAAGCGGTGGGATTAATGTAAATAATGCAATTGCATTTGGT
CACATTGAAAATCCCGAACAATTTCCGTATTTGTTAGAGGAACAAGTAAATGTAGATGAT
TCAAGAAATTATCCCTCGTATGCTGCACAGAAAATGGATGATTTCGATAACAATTATCCT
CCTATAATGGAACAACAACAGCACAATCATGTCGATAATCCGAGGCAATTCAATTTGCCA
AATGCTGTACGCACGCAACCAAAAATTGTCGATTTCGATCAAATGACGTGTCTATTCGGT
GGCAATGTACATAATAAAATTCCAATTCGTAAATTGAATCCAAATCTCTTTCTTTGCAAA
TATACAAATGTGTGCATGAAAAGCTGTCAATGTTGCGAAAATTTCTCATGTGATTGTCAA
CAAAAATGTCCAGATAGATGTAACTGTTATCACAATACAAATTGGGATGTTAATTTTGTG
AACTGTTCTTCAGCCAACTACACAAAATCATTTCCCAATCTCATTCCTATGGAGGCTACT
CATCTCCATCTAGACGGCAATCACTTTGAAATGATTAAAGATTTTTCATTCATTGGAAGA
CGTGCGTTACGTATTCTCTATCTAAATCATTCACATATTCAACAATTGACAAATCGCACG
TTTTTTGGACTCAAGCATCTAGAGCTATTGAGTTTAAAGAGCAATGAGTTGCAACAACTC
AATGGTGACGAGTTCAATGAGCTTGAAAGTGTCAAGTATCTATTTCTACAGTACAATCAT
ATAAAGTTCATTGAGCGCAAAACATTTGGACAATTACGTCAGCTGCAAGTGCTCAAGCTC
AATGGCAACATGCTTATGACACTCAATCTTCAATTTCTGCCTCAAAATGTCGCACAAATA
GACATTAGCGAAAATCTTCTTGAATGCGATTGTGAACTTATAAAAAGTCTCAAGGTGCAT
CATGCTATTGACTATCGTGACTCACTTAAGTGCCATCCAAATCAAACTTATCATGAGTAC
TTTTATGTTATGAACGAGACAAACTTTTGCAATGAGAAGCTGGCACTTGAGAATATTTTC
TTTTTTGAAAAGAATCTACCAATATTTCTCATTGTATTTCTCTGTTGTCTCTTCCTTATC
GTGCTAGTCTTTATTTTTAATCAACACATAATGTTTTGTTGCTATAAAAAGTTCAATTTG
AGATTCTTTAAGAAGCGTAATGATAAGAATAAATTCTTTGATGGATTTCTAGTTTTTAGT
AAAAAGGATGAAAATTTTTTGCTCGATGAGTTCCTTAAGCATTTTGAAACAGAAGGAAAT
TATTATAAATTCTTTCTCTTCTTCCACGATTTTTCAATTTTCAATGAACAGATATTGAAG
AATTCGGAAAATTCGCAGAAAATTATTCTCTTTTTATCAGAGAACTTTCTTAAGAACGAA
TGGAAGAAAATTGAGTTTAAGAAAATTTTCTATGAAATACTTAAGACAAAGAAGCGAAAG
AAGCTCATAATTGTGTTCCTTGATAATTTCGATAATAAAAACTTTGATCCCGAGCTCAAG
CTCATTCTCAAGACCAACTTCATTTTACGATGGAACGAAAAGTTGTTTTGGGAGAAGTTT
AAATTTTTCTTGCCAAGTCTAAATCGTAATGCTCAGTTGCAAACTCAACAACAACAAACA
ACGTCATCTCATCATGACCCCGAAAACTTTTGTCAAAATTTCCATCTAAATAATCTTCAT
AACAATCACCATCATCCAAGTCCTCAGCGCAATCTTACATCAATTCATATTTAG

>g3317.t1 Gene=g3317 Length=1297
MKHRRYSFMTSTVIYCCLILVLNHKISSIAQSTSNEECSYETIDESLLMTLSNDQNISNT
KLLSCRFKKLPKTFPIASAKSVENLKIICDKLLFANGGDSGSKSSNFFDNFENLKNLFLE
NCDGNFLRNFNSLKSLNGLTIRNYKTFWGRYDEVMDDFGTSNDYEPFDNLQNIKSLDISD
NGIQELHRNFFCDFHKLSFLNISSNQIYNLTNFQFSSTPIKNCVFSMSYLILTNNQLNFL
PFSFFSNFVNLKVLRLNRNSISFIENFVFSNLKQLDMLDLSENKIQSIQPELFDNLQNLR
TLNLEKNSMKILPPELLANLKKLELLNLSSNFLSSNWINFMTFKNLFNLRLLDLSYNKLT
ALENSVFADLAALEVLDLKNNLIESIAMDTFANLTSLSSLVLSHNFIKNVNFSLNSLTNL
NVLSLDFNEIYSVEKHLVANSMKLVDLHLNNNKFFRVPTFVENFQFLKFLDLGENFIKNL
SDLENLPNLKYLYGLRLTENQIETLEKNHFVHLKNLQIVNLSKNRIRHIDRESFAANEFL
QAIRLDGNSIKNIDYMFENLTQLVFLNISENALEVFDYENFPKNLQFLDISKNQINVIKN
PNEISQNLKTLNLNYNHLTEISAFVLPRNLEDLYLQSNLIEKISPYTFIKKSFLKTVDLK
HNRIAHLNENALRISSTKSDEKLPEFHLAGNPLVCDCHLKWMWQDNISGGINVNNAIAFG
HIENPEQFPYLLEEQVNVDDSRNYPSYAAQKMDDFDNNYPPIMEQQQHNHVDNPRQFNLP
NAVRTQPKIVDFDQMTCLFGGNVHNKIPIRKLNPNLFLCKYTNVCMKSCQCCENFSCDCQ
QKCPDRCNCYHNTNWDVNFVNCSSANYTKSFPNLIPMEATHLHLDGNHFEMIKDFSFIGR
RALRILYLNHSHIQQLTNRTFFGLKHLELLSLKSNELQQLNGDEFNELESVKYLFLQYNH
IKFIERKTFGQLRQLQVLKLNGNMLMTLNLQFLPQNVAQIDISENLLECDCELIKSLKVH
HAIDYRDSLKCHPNQTYHEYFYVMNETNFCNEKLALENIFFFEKNLPIFLIVFLCCLFLI
VLVFIFNQHIMFCCYKKFNLRFFKKRNDKNKFFDGFLVFSKKDENFLLDEFLKHFETEGN
YYKFFLFFHDFSIFNEQILKNSENSQKIILFLSENFLKNEWKKIEFKKIFYEILKTKKRK
KLIIVFLDNFDNKNFDPELKLILKTNFILRWNEKLFWEKFKFFLPSLNRNAQLQTQQQQT
TSSHHDPENFCQNFHLNNLHNNHHHPSPQRNLTSIHI

Protein features from InterProScan

Transcript Database ID Name Start End E.value
21 g3317.t1 Gene3D G3DSA:3.80.10.10 Ribonuclease Inhibitor 10 219 5.6E-12
24 g3317.t1 Gene3D G3DSA:3.80.10.10 Ribonuclease Inhibitor 220 337 8.6E-24
23 g3317.t1 Gene3D G3DSA:3.80.10.10 Ribonuclease Inhibitor 338 457 6.1E-23
20 g3317.t1 Gene3D G3DSA:3.80.10.10 Ribonuclease Inhibitor 458 600 2.8E-24
22 g3317.t1 Gene3D G3DSA:3.80.10.10 Ribonuclease Inhibitor 601 723 9.4E-23
19 g3317.t1 Gene3D G3DSA:3.80.10.10 Ribonuclease Inhibitor 842 942 6.3E-18
18 g3317.t1 Gene3D G3DSA:3.80.10.10 Ribonuclease Inhibitor 943 1053 5.6E-14
17 g3317.t1 Gene3D G3DSA:3.40.50.10140 - 1102 1251 4.8E-24
8 g3317.t1 PANTHER PTHR45836:SF8 TOLL-LIKE RECEPTOR 6 39 704 2.5E-203
10 g3317.t1 PANTHER PTHR45836 SLIT HOMOLOG 39 704 2.5E-203
7 g3317.t1 PANTHER PTHR45836:SF8 TOLL-LIKE RECEPTOR 6 782 1289 2.5E-203
9 g3317.t1 PANTHER PTHR45836 SLIT HOMOLOG 782 1289 2.5E-203
1 g3317.t1 Pfam PF13855 Leucine rich repeat 165 207 9.2E-7
3 g3317.t1 Pfam PF13855 Leucine rich repeat 274 331 7.9E-13
5 g3317.t1 Pfam PF13855 Leucine rich repeat 348 405 1.5E-14
2 g3317.t1 Pfam PF13855 Leucine rich repeat 492 550 1.4E-10
4 g3317.t1 Pfam PF13855 Leucine rich repeat 926 985 4.1E-11
6 g3317.t1 Pfam PF01582 TIR domain 1116 1235 4.7E-6
27 g3317.t1 Phobius SIGNAL_PEPTIDE Signal peptide region 1 30 -
28 g3317.t1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 10 -
29 g3317.t1 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 11 22 -
31 g3317.t1 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 23 30 -
26 g3317.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 31 1067 -
30 g3317.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 1068 1095 -
25 g3317.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 1096 1297 -
96 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 113 137 4.901
90 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 172 193 6.326
94 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 196 217 7.466
79 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 226 247 4.87
98 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 250 271 7.335
77 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 274 295 7.496
91 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 298 319 5.979
84 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 322 342 5.525
101 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 348 369 7.727
86 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 372 393 7.08
83 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 396 418 6.688
92 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 419 440 6.002
88 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 443 464 5.394
82 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 466 487 8.598
97 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 491 512 5.109
99 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 515 536 7.158
103 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 539 561 5.263
102 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 562 583 4.909
93 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 584 605 6.957
81 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 607 628 7.781
78 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 629 650 8.112
95 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 653 674 5.756
89 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 878 899 4.978
87 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 902 923 5.325
100 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 926 947 6.141
80 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 950 971 5.463
85 g3317.t1 ProSiteProfiles PS51450 Leucine-rich repeat profile. 974 994 6.218
104 g3317.t1 ProSiteProfiles PS50104 TIR domain profile. 1111 1247 16.79
33 g3317.t1 SMART SM00364 LRR_bac_2 170 189 480.0
54 g3317.t1 SMART SM00369 LRR_typ_2 170 193 5.4
75 g3317.t1 SMART SM00365 LRR_sd22_2 170 188 110.0
39 g3317.t1 SMART SM00364 LRR_bac_2 194 213 180.0
45 g3317.t1 SMART SM00369 LRR_typ_2 194 217 110.0
72 g3317.t1 SMART SM00365 LRR_sd22_2 194 215 700.0
48 g3317.t1 SMART SM00369 LRR_typ_2 224 247 40.0
50 g3317.t1 SMART SM00369 LRR_typ_2 248 271 1.3
63 g3317.t1 SMART SM00365 LRR_sd22_2 248 269 180.0
52 g3317.t1 SMART SM00369 LRR_typ_2 272 295 0.0077
62 g3317.t1 SMART SM00365 LRR_sd22_2 272 298 13.0
37 g3317.t1 SMART SM00364 LRR_bac_2 296 316 440.0
51 g3317.t1 SMART SM00369 LRR_typ_2 296 319 0.26
55 g3317.t1 SMART SM00369 LRR_typ_2 320 345 340.0
73 g3317.t1 SMART SM00365 LRR_sd22_2 320 342 770.0
60 g3317.t1 SMART SM00369 LRR_typ_2 346 369 0.004
71 g3317.t1 SMART SM00365 LRR_sd22_2 346 367 120.0
53 g3317.t1 SMART SM00369 LRR_typ_2 370 393 0.24
68 g3317.t1 SMART SM00365 LRR_sd22_2 370 391 260.0
49 g3317.t1 SMART SM00369 LRR_typ_2 394 414 180.0
69 g3317.t1 SMART SM00365 LRR_sd22_2 394 412 320.0
57 g3317.t1 SMART SM00369 LRR_typ_2 417 440 8.3
67 g3317.t1 SMART SM00365 LRR_sd22_2 417 435 740.0
35 g3317.t1 SMART SM00364 LRR_bac_2 464 483 27.0
61 g3317.t1 SMART SM00365 LRR_sd22_2 464 485 25.0
42 g3317.t1 SMART SM00369 LRR_typ_2 486 512 150.0
43 g3317.t1 SMART SM00369 LRR_typ_2 513 536 0.04
74 g3317.t1 SMART SM00365 LRR_sd22_2 513 534 490.0
58 g3317.t1 SMART SM00369 LRR_typ_2 560 583 300.0
34 g3317.t1 SMART SM00364 LRR_bac_2 582 601 510.0
65 g3317.t1 SMART SM00365 LRR_sd22_2 582 603 18.0
36 g3317.t1 SMART SM00364 LRR_bac_2 605 624 2.0
59 g3317.t1 SMART SM00369 LRR_typ_2 606 626 110.0
66 g3317.t1 SMART SM00365 LRR_sd22_2 627 648 22.0
44 g3317.t1 SMART SM00369 LRR_typ_2 628 650 27.0
41 g3317.t1 SMART SM00369 LRR_typ_2 652 674 370.0
56 g3317.t1 SMART SM00369 LRR_typ_2 901 923 56.0
47 g3317.t1 SMART SM00369 LRR_typ_2 924 947 34.0
64 g3317.t1 SMART SM00365 LRR_sd22_2 924 945 100.0
40 g3317.t1 SMART SM00369 LRR_typ_2 948 971 3.9
70 g3317.t1 SMART SM00365 LRR_sd22_2 948 969 280.0
46 g3317.t1 SMART SM00369 LRR_typ_2 972 994 59.0
38 g3317.t1 SMART SM00364 LRR_bac_2 994 1013 220.0
76 g3317.t1 SMART SM00255 till_3 1112 1247 1.8E-10
13 g3317.t1 SUPERFAMILY SSF52058 L domain-like 103 492 2.38E-47
14 g3317.t1 SUPERFAMILY SSF52058 L domain-like 391 705 9.86E-46
12 g3317.t1 SUPERFAMILY SSF52058 L domain-like 844 1026 9.07E-24
11 g3317.t1 SUPERFAMILY SSF52200 Toll/Interleukin receptor TIR domain 1106 1248 1.06E-19
16 g3317.t1 SignalP_EUK SignalP-noTM SignalP-noTM 1 28 -
15 g3317.t1 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM 1 30 -
32 g3317.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 1065 1087 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0007165 signal transduction BP
GO:0005515 protein binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed