Gene loci information

Transcript annotation

  • This transcript has been annotated as Inositol-trisphosphate 3-kinase B.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3321 g3321.t1 TTS g3321.t1 24633755 24633755
chr_3 g3321 g3321.t1 isoform g3321.t1 24633989 24638787
chr_3 g3321 g3321.t1 exon g3321.t1.exon1 24633989 24634312
chr_3 g3321 g3321.t1 cds g3321.t1.CDS1 24633989 24634312
chr_3 g3321 g3321.t1 exon g3321.t1.exon2 24634399 24634557
chr_3 g3321 g3321.t1 cds g3321.t1.CDS2 24634399 24634557
chr_3 g3321 g3321.t1 exon g3321.t1.exon3 24634648 24634737
chr_3 g3321 g3321.t1 cds g3321.t1.CDS3 24634648 24634737
chr_3 g3321 g3321.t1 exon g3321.t1.exon4 24634798 24634931
chr_3 g3321 g3321.t1 cds g3321.t1.CDS4 24634798 24634931
chr_3 g3321 g3321.t1 exon g3321.t1.exon5 24635008 24635241
chr_3 g3321 g3321.t1 cds g3321.t1.CDS5 24635008 24635241
chr_3 g3321 g3321.t1 exon g3321.t1.exon6 24635307 24635340
chr_3 g3321 g3321.t1 cds g3321.t1.CDS6 24635307 24635340
chr_3 g3321 g3321.t1 exon g3321.t1.exon7 24637132 24637661
chr_3 g3321 g3321.t1 cds g3321.t1.CDS7 24637132 24637661
chr_3 g3321 g3321.t1 exon g3321.t1.exon8 24638649 24638787
chr_3 g3321 g3321.t1 cds g3321.t1.CDS8 24638649 24638787
chr_3 g3321 g3321.t1 TSS g3321.t1 24638764 24638764

Sequences

>g3321.t1 Gene=g3321 Length=1644
ATGTACATGGCTTTGCCGTCTCTCAGTAATAATAATAGTACCAAACCAACCACAACAATT
AAATTCAATATACCAACTTTAACTATAATTGAAGATTTTGATAAATTGATTGCTAAAGAA
GTGATTTTTGACGAGTCAGGCGAGAAGCATATCGTCAAATTGCTTCATTTTCCAAATATC
ACACCGAGTGAACAGAAACGACTTCTCATGTCTGACAACGACGATTCAGGTTCAGGCTCA
GATAATGAAGAAGAGCAAAATGATGGAACATTTCATCAAAAAACACAAAGAAAAAAATCT
TCTACCAAAAGATCTCTCGATTTACAACGGAAAATTTCACAAAGCAAAATTAAAGAGGAG
AAAAGAGAAGCAAAACAGCACTCAAACAGCAATGGAATCCATGTGTCAGTAACAACTCAA
AACAACAGTTCAGAGCCAACCGCTCCTATTCAAATTCCCTCGATTTCATTGAAGCATGGT
CGAAGTCGAACGACACGAAATGGAAAAATATCAGGTGGCTATGAGCAGTTTAGTCAAAGT
CTTCTCACTGTGCCAATGCCCAAAGATTATTGTGATCCAAGCAGTGATGATTTGTCTAGT
GAATGGGATTCTGATTCAGTCAATGAGAGCAATAATAAAACAAATGGAACCACAAATAAG
GAACCTAAGTCAGTGGTTGGATGGAGGAAACTTAGAAATATAGTTCAATGGACACCATTT
TTTCAAACGTATTCAAAAAATAAACAAAAATATCCATGGGTTCAACTTGCTGGTCATCAG
GGAAATTTTAAAGCAGGTCTTGATGCCGGAACTGTGCTAAAAAAATTAACGCCAAAAGAA
GAGATTTGTTTTAAAGAGCTCATGAAAGACGTACTAAGACCATATGTACCAGAATTCAGA
GGCGTCTGTAATGTTGAAGGCAGTGACGATAATGAATCTCAATATTTACAGCTTCAAGAT
CTGTTGAGTGATTTCAATAAACCATTTTGTGTTATGGACATTAAAATCGGAGTGAGAACG
TATTTAGAGGAAGAGTTGTTTAAGGCAAAAGAGAAACAAAAGTTAAGAAAAGATATGTAT
GAAAAAATGATTCAGGTTGATCCAAATGCACCAAGTGCGGAAGAACATGAAGCCAAAGGT
GTAACAAAACCACGTTATATGGTTTGGCGTGAAACGATTTCAAGTACGGCAAATTTAGGA
TTCCGCATCGAAGGTATTAAAAAAGACGATTTCAAGACGAAAGACTTTAAAACGATAAAA
TCACGTGAGGACATCACTGAAATGTTTAAAGAGTTCTTCAAAGGTTACCCACTCGCATTG
CGGAAATATATTCAGCGCCTCAAAGCAATTCGAGCCACACTTGAACATTCAGATTTCTTC
AAGAGTCATGAAATCATTGGAAGTAGTCTTTTATTTGTGCATGATCGCAATAATGCAAGC
TGTTGGTTGATTGATTTTGCCAAAACGGGAGTTGTGCCTGAAAATATTAAAATTACGCAC
AAAGATCAATGGGAAGTCGGAAATCACGAGGATGGCTATCTAATTGGACTTAATAATATT
ATCGAAATGTTTGACGATATTGCAAGACAAACGGAAAATTTTCATAAATCTGATGACGAT
GATCAAACAGATTCGAGTGATTGA

>g3321.t1 Gene=g3321 Length=547
MYMALPSLSNNNSTKPTTTIKFNIPTLTIIEDFDKLIAKEVIFDESGEKHIVKLLHFPNI
TPSEQKRLLMSDNDDSGSGSDNEEEQNDGTFHQKTQRKKSSTKRSLDLQRKISQSKIKEE
KREAKQHSNSNGIHVSVTTQNNSSEPTAPIQIPSISLKHGRSRTTRNGKISGGYEQFSQS
LLTVPMPKDYCDPSSDDLSSEWDSDSVNESNNKTNGTTNKEPKSVVGWRKLRNIVQWTPF
FQTYSKNKQKYPWVQLAGHQGNFKAGLDAGTVLKKLTPKEEICFKELMKDVLRPYVPEFR
GVCNVEGSDDNESQYLQLQDLLSDFNKPFCVMDIKIGVRTYLEEELFKAKEKQKLRKDMY
EKMIQVDPNAPSAEEHEAKGVTKPRYMVWRETISSTANLGFRIEGIKKDDFKTKDFKTIK
SREDITEMFKEFFKGYPLALRKYIQRLKAIRATLEHSDFFKSHEIIGSSLLFVHDRNNAS
CWLIDFAKTGVVPENIKITHKDQWEVGNHEDGYLIGLNNIIEMFDDIARQTENFHKSDDD
DQTDSSD

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g3321.t1 Gene3D G3DSA:1.10.510.50 - 262 530 7.8E-111
9 g3321.t1 MobiDBLite mobidb-lite consensus disorder prediction 72 173 -
6 g3321.t1 MobiDBLite mobidb-lite consensus disorder prediction 85 128 -
7 g3321.t1 MobiDBLite mobidb-lite consensus disorder prediction 129 173 -
8 g3321.t1 MobiDBLite mobidb-lite consensus disorder prediction 192 223 -
5 g3321.t1 MobiDBLite mobidb-lite consensus disorder prediction 204 222 -
2 g3321.t1 PANTHER PTHR12400:SF85 KINASE 156 537 7.0E-172
3 g3321.t1 PANTHER PTHR12400 INOSITOL POLYPHOSPHATE KINASE 156 537 7.0E-172
1 g3321.t1 Pfam PF03770 Inositol polyphosphate kinase 315 524 2.5E-37
4 g3321.t1 SUPERFAMILY SSF56104 SAICAR synthase-like 251 528 1.14E-81

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016301 kinase activity MF
GO:0032958 inositol phosphate biosynthetic process BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values