Gene loci information

Transcript annotation

  • This transcript has been annotated as Inositol-trisphosphate 3-kinase B.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3321 g3321.t4 TTS g3321.t4 24633755 24633755
chr_3 g3321 g3321.t4 isoform g3321.t4 24633989 24635429
chr_3 g3321 g3321.t4 exon g3321.t4.exon1 24633989 24634312
chr_3 g3321 g3321.t4 cds g3321.t4.CDS1 24633989 24634312
chr_3 g3321 g3321.t4 exon g3321.t4.exon2 24634399 24634557
chr_3 g3321 g3321.t4 cds g3321.t4.CDS2 24634399 24634557
chr_3 g3321 g3321.t4 exon g3321.t4.exon3 24634648 24634737
chr_3 g3321 g3321.t4 cds g3321.t4.CDS3 24634648 24634737
chr_3 g3321 g3321.t4 exon g3321.t4.exon4 24634798 24634931
chr_3 g3321 g3321.t4 cds g3321.t4.CDS4 24634798 24634931
chr_3 g3321 g3321.t4 exon g3321.t4.exon5 24635008 24635241
chr_3 g3321 g3321.t4 cds g3321.t4.CDS5 24635008 24635083
chr_3 g3321 g3321.t4 exon g3321.t4.exon6 24635307 24635340
chr_3 g3321 g3321.t4 exon g3321.t4.exon7 24635408 24635429
chr_3 g3321 g3321.t4 TSS g3321.t4 24635430 24635430

Sequences

>g3321.t4 Gene=g3321 Length=997
TTTGTACTTAAGACTCAGAGAGTCAGTGGTTGGATGGAGGAAACTTAGAAATATAGTTCA
ATGGACACCATTTTTTCAAACGTATTCAAAAAATAAACAAAAATATCCATGGGTTCAACT
TGCTGGTCATCAGGGAAATTTTAAAGCAGGTCTTGATGCCGGAACTGTGCTAAAAAAATT
AACGCCAAAAGAAGAGATTTGTTTTAAAGAGCTCATGAAAGACGTACTAAGACCATATGT
ACCAGAATTCAGAGGCGTCTGTAATGTTGAAGGCAGTGACGATAATGAATCTCAATATTT
ACAGCTTCAAGATCTGTTGAGTGATTTCAATAAACCATTTTGTGTTATGGACATTAAAAT
CGGAGTGAGAACGTATTTAGAGGAAGAGTTGTTTAAGGCAAAAGAGAAACAAAAGTTAAG
AAAAGATATGTATGAAAAAATGATTCAGGTTGATCCAAATGCACCAAGTGCGGAAGAACA
TGAAGCCAAAGGTGTAACAAAACCACGTTATATGGTTTGGCGTGAAACGATTTCAAGTAC
GGCAAATTTAGGATTCCGCATCGAAGGTATTAAAAAAGACGATTTCAAGACGAAAGACTT
TAAAACGATAAAATCACGTGAGGACATCACTGAAATGTTTAAAGAGTTCTTCAAAGGTTA
CCCACTCGCATTGCGGAAATATATTCAGCGCCTCAAAGCAATTCGAGCCACACTTGAACA
TTCAGATTTCTTCAAGAGTCATGAAATCATTGGAAGTAGTCTTTTATTTGTGCATGATCG
CAATAATGCAAGCTGTTGGTTGATTGATTTTGCCAAAACGGGAGTTGTGCCTGAAAATAT
TAAAATTACGCACAAAGATCAATGGGAAGTCGGAAATCACGAGGATGGCTATCTAATTGG
ACTTAATAATATTATCGAAATGTTTGACGATATTGCAAGACAAACGGAAAATTTTCATAA
ATCTGATGACGATGATCAAACAGATTCGAGTGATTGA

>g3321.t4 Gene=g3321 Length=260
MKDVLRPYVPEFRGVCNVEGSDDNESQYLQLQDLLSDFNKPFCVMDIKIGVRTYLEEELF
KAKEKQKLRKDMYEKMIQVDPNAPSAEEHEAKGVTKPRYMVWRETISSTANLGFRIEGIK
KDDFKTKDFKTIKSREDITEMFKEFFKGYPLALRKYIQRLKAIRATLEHSDFFKSHEIIG
SSLLFVHDRNNASCWLIDFAKTGVVPENIKITHKDQWEVGNHEDGYLIGLNNIIEMFDDI
ARQTENFHKSDDDDQTDSSD

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g3321.t4 Gene3D G3DSA:1.10.510.50 - 1 243 0
2 g3321.t4 PANTHER PTHR12400:SF85 KINASE 1 250 0
3 g3321.t4 PANTHER PTHR12400 INOSITOL POLYPHOSPHATE KINASE 1 250 0
1 g3321.t4 Pfam PF03770 Inositol polyphosphate kinase 28 237 0
4 g3321.t4 SUPERFAMILY SSF56104 SAICAR synthase-like 2 240 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016301 kinase activity MF
GO:0032958 inositol phosphate biosynthetic process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values