General information for g3365.t17
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 6-phosphogluconate dehydrogenase, decarboxylating.
Parent gene
- The parent gene g3365 is located on chr_3: 24878799..24880042 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3365 | g3365.t17 | isoform | g3365.t17 | 24878561 | 24879862 |
| chr_3 | g3365 | g3365.t17 | exon | g3365.t17.exon1 | 24878561 | 24878810 |
| chr_3 | g3365 | g3365.t17 | cds | g3365.t17.CDS1 | 24878563 | 24878810 |
| chr_3 | g3365 | g3365.t17 | exon | g3365.t17.exon2 | 24879231 | 24879345 |
| chr_3 | g3365 | g3365.t17 | cds | g3365.t17.CDS2 | 24879231 | 24879345 |
| chr_3 | g3365 | g3365.t17 | exon | g3365.t17.exon3 | 24879649 | 24879757 |
| chr_3 | g3365 | g3365.t17 | cds | g3365.t17.CDS3 | 24879649 | 24879757 |
| chr_3 | g3365 | g3365.t17 | exon | g3365.t17.exon4 | 24879855 | 24879862 |
| chr_3 | g3365 | g3365.t17 | cds | g3365.t17.CDS4 | 24879855 | 24879862 |
| chr_3 | g3365 | g3365.t17 | TSS | g3365.t17 | 24879992 | 24879992 |
| chr_3 | g3365 | g3365.t17 | TTS | g3365.t17 | NA | NA |
Sequences
>g3365.t17 Gene=g3365 Length=482
ATGGCACAAAAAGCTGATATCGCATTAATTGGGCTCGCAGTGATGGGTCAAAATTTGATA
CTTAATATGGATTCAAAAGGTTTCGTTGTGTGTGCATTTAATCGTACTGTCGATAAGGTC
AAGCAATTTTTGGAAAATGAGGCAAAGGGAACAAAAATAATCGGTGCAACATCAATGGAA
GATATGGTTAGCAAATTGAAGACTCCTCGACGTGTTATGCTTCTGGTCAAAGCTGGGAGT
GCTGTTGATGATTTTATCAAACAATTAACTCCATTACTTTCACCTGGTGATATCATCATT
GATGGTGGAAATTCTGAATATCAAGATACTGCAAGACGTGTTGAAGAATGCAAAAAGAAT
AAATTATTGTTTGTTGGTTCAGGTGTAAGCGGAGGTGAAGAAGGTGCACGTTATGGACCA
TCATTAATGCCTGGCGGTAATCCTGAAGCTTGGCCACATATTAAAGACATTTTCCAATCA
AT
>g3365.t17 Gene=g3365 Length=160
MAQKADIALIGLAVMGQNLILNMDSKGFVVCAFNRTVDKVKQFLENEAKGTKIIGATSME
DMVSKLKTPRRVMLLVKAGSAVDDFIKQLTPLLSPGDIIIDGGNSEYQDTARRVEECKKN
KLLFVGSGVSGGEEGARYGPSLMPGGNPEAWPHIKDIFQS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g3365.t17 | Gene3D | G3DSA:3.40.50.720 | - | 1 | 160 | 0 |
| 2 | g3365.t17 | PANTHER | PTHR11811:SF50 | 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING | 4 | 159 | 0 |
| 3 | g3365.t17 | PANTHER | PTHR11811 | 6-PHOSPHOGLUCONATE DEHYDROGENASE | 4 | 159 | 0 |
| 5 | g3365.t17 | PRINTS | PR00076 | 6-phosphogluconate dehydrogenase signature | 5 | 28 | 0 |
| 6 | g3365.t17 | PRINTS | PR00076 | 6-phosphogluconate dehydrogenase signature | 68 | 97 | 0 |
| 4 | g3365.t17 | PRINTS | PR00076 | 6-phosphogluconate dehydrogenase signature | 121 | 146 | 0 |
| 1 | g3365.t17 | Pfam | PF03446 | NAD binding domain of 6-phosphogluconate dehydrogenase | 6 | 159 | 0 |
| 7 | g3365.t17 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 5 | 159 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0050661 | NADP binding | MF |
| GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
