General information for g3365.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 6-phosphogluconate dehydrogenase, decarboxylating.
Parent gene
- The parent gene g3365 is located on chr_3: 24878799..24880042 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3365 | g3365.t3 | TTS | g3365.t3 | 24877436 | 24877436 |
| chr_3 | g3365 | g3365.t3 | isoform | g3365.t3 | 24877527 | 24878679 |
| chr_3 | g3365 | g3365.t3 | exon | g3365.t3.exon1 | 24877527 | 24878453 |
| chr_3 | g3365 | g3365.t3 | cds | g3365.t3.CDS1 | 24877527 | 24878453 |
| chr_3 | g3365 | g3365.t3 | exon | g3365.t3.exon2 | 24878524 | 24878679 |
| chr_3 | g3365 | g3365.t3 | cds | g3365.t3.CDS2 | 24878524 | 24878616 |
| chr_3 | g3365 | g3365.t3 | TSS | g3365.t3 | NA | NA |
Sequences
>g3365.t3 Gene=g3365 Length=1083
TTATTGTTTGTTGGTTCAGGTGTAAGCGGAGGTGAAGAAGGTGCACGTTATGGACCATCA
TTAATGCCTGGCGGTAATCCTGAAGCTTGGCCACATATTAAAGACATTTTCCAATCAATC
TGTGCACGTGCTGACAATGAACCTTGTTGTGAGTGGGTCGGTGAAGGCGGTAGCGGTCAT
TTTGTTAAAATGGTACATAATGGAATTGAGTATGGTGATATGCAACTAATTTGTGAAGCA
TATGATTTAATGAAAGCAATGGGTATGAGTCAAAAAGAAATGGCTGATGCATTTACTGAA
TGGAACAAAGGCGAACTTGATTCTTTCCTCATTGAAATTACCAGTAGTATTCTCAATTAT
AAAGATAAGGAAGGATATTTGCTTGAACGTATTCGTGACACTGCTGGTCAAAAAGGTACT
GGGAAATGGACTGCAATTGCTGCTCTTCAATACGGTGTACCCGTTACTCTAATTGGTGAA
GCTGTCTTCTCTCGTTGCTTATCTGCTCTTAAAAGTGAACGAGTTGCTGCAAGCAAAGTA
CTGAATGGTCCAGACACAAAACCAACTGTCGCTAACAAGGCTGAATTCTTGAATCACATT
AAGAATGCTCTTTATTGTGCAAAAATTGTTTCATATGCTCAAGGTTTTATGTTGATGCGT
GAGGCTGCAAAGGAAAATGGCTGGCACTTAAATTATGGCGGTATTGCTTTGATGTGGAGA
GGTGGTTGCATCATAAGAAGTGTATTCTTAGGAAACATTAAAGAAGCATTCACTCGTAAT
CCACAATTATCAAATTTATTACTTGATGACTTTTTCAAGAATGCAATTACTAAAAATCAA
AATTCCTGGCGACAAGTTGTATCAAATGCGACACTTTGGGGAATTCCAGTTCCAGCACTT
TCAGCTGCTCTTGCCTTCTTTGACGGCTATCGTGCTGATCGTCTTCCGGCTAATCTATTG
CAAGCACAAAGAGACTTCTTTGGTGCTCATACATATGAATTGTTAGGTCAAGAGGGCAAA
TTTGTTCATACAAATTGGACTGGAACTGGTGGAAATGTTAGTGCATCATCATATAATGCA
TAA
>g3365.t3 Gene=g3365 Length=339
MPGGNPEAWPHIKDIFQSICARADNEPCCEWVGEGGSGHFVKMVHNGIEYGDMQLICEAY
DLMKAMGMSQKEMADAFTEWNKGELDSFLIEITSSILNYKDKEGYLLERIRDTAGQKGTG
KWTAIAALQYGVPVTLIGEAVFSRCLSALKSERVAASKVLNGPDTKPTVANKAEFLNHIK
NALYCAKIVSYAQGFMLMREAAKENGWHLNYGGIALMWRGGCIIRSVFLGNIKEAFTRNP
QLSNLLLDDFFKNAITKNQNSWRQVVSNATLWGIPVPALSAALAFFDGYRADRLPANLLQ
AQRDFFGAHTYELLGQEGKFVHTNWTGTGGNVSASSYNA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g3365.t3 | Gene3D | G3DSA:3.40.50.720 | - | 1 | 41 | 4.7E-7 |
| 10 | g3365.t3 | Gene3D | G3DSA:1.10.1040.10 | - | 42 | 292 | 3.2E-110 |
| 9 | g3365.t3 | Gene3D | G3DSA:1.20.5.320 | - | 293 | 339 | 2.8E-25 |
| 2 | g3365.t3 | PANTHER | PTHR11811:SF50 | 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING | 1 | 338 | 1.9E-158 |
| 3 | g3365.t3 | PANTHER | PTHR11811 | 6-PHOSPHOGLUCONATE DEHYDROGENASE | 1 | 338 | 1.9E-158 |
| 5 | g3365.t3 | PRINTS | PR00076 | 6-phosphogluconate dehydrogenase signature | 27 | 55 | 1.9E-36 |
| 6 | g3365.t3 | PRINTS | PR00076 | 6-phosphogluconate dehydrogenase signature | 106 | 133 | 1.9E-36 |
| 4 | g3365.t3 | PRINTS | PR00076 | 6-phosphogluconate dehydrogenase signature | 214 | 236 | 1.9E-36 |
| 1 | g3365.t3 | Pfam | PF00393 | 6-phosphogluconate dehydrogenase, C-terminal domain | 38 | 325 | 9.8E-130 |
| 11 | g3365.t3 | ProSitePatterns | PS00461 | 6-phosphogluconate dehydrogenase signature. | 110 | 122 | - |
| 12 | g3365.t3 | SMART | SM01350 | 6PGD_2 | 38 | 326 | 1.3E-214 |
| 7 | g3365.t3 | SUPERFAMILY | SSF48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like | 36 | 329 | 1.9E-129 |
| 13 | g3365.t3 | TIGRFAM | TIGR00873 | gnd: 6-phosphogluconate dehydrogenase (decarboxylating) | 1 | 326 | 2.1E-152 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006098 | pentose-phosphate shunt | BP |
| GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
