Gene loci information

Transcript annotation

  • This transcript has been annotated as Probable maleylacetoacetate isomerase 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3485 g3485.t2 isoform g3485.t2 25938860 25939939
chr_3 g3485 g3485.t2 exon g3485.t2.exon1 25938860 25939208
chr_3 g3485 g3485.t2 TSS g3485.t2 25938878 25938878
chr_3 g3485 g3485.t2 exon g3485.t2.exon2 25939437 25939939
chr_3 g3485 g3485.t2 cds g3485.t2.CDS1 25939587 25939937
chr_3 g3485 g3485.t2 TTS g3485.t2 25940278 25940278

Sequences

>g3485.t2 Gene=g3485 Length=852
GCACAACCGGTGGTGAAATAAATTGAAGGATAACAAAACAGAAAGAAAAATATTTTTACT
TAAAAATTAAAATATTTATTTTCTAACATTCCATATCTTTACAAAAAATTTCCAAAATTA
ATTACTCAAAGTACAATAACTCCCTGCAACCAGGGATTAAGGTAGTGAGTTCAAATAACA
TCAAAATCAGTAGATAAAGTTAAACTTTTGCTTGTGTGATTTATTTTTTACGCTCATAGT
ACGATTTGTTTACAAATTATTTTTATTTATTTTTGAGAGATTTTATGATTTGGTTATTTT
GTTTTTATCAAACCGCATTTTGTGTGATACATCATGAATAAACTGGCAACCAATACTTTA
TTCTTACTGGCGCTCGAGTTGCAGTTGGAGAGTCCGAATATGCCTCAATCTCAAGGAAAT
TCCTTATGATATAAAGCCAATTAGCTTGATCAAATCAGGCGGTGAGCAGCATTGTAATGA
ATATCGCGAAGTCAATCCAATGGAGCAAGTACCCGCATTACAAATTGATGGTCACACACT
CGTTGAATCACTGGCAATAATGCAGTATTTAGAAGAAACGCGACCACAACGTCCACTCAT
GCCGCAGGACTTCCATAAGCGAGCTAAAGTTCGTGAATTATGTGAAATTATTGCATCAGG
AATTCAACCATTGCAGAATTTGATTGTGCTGATTCATGTTGGTGAAGAAAAGAAAAAAGA
ATGGGCACAACATTGGATCACGAGAGGATTTAGAGCTGTTGAAAAACTTTTATCTACTAG
CGCTGGCAAGTATTGTGTCGGTGATGAAATCACCCTTGCTGACTGCTGTCTGATTCCTCA
AGTTTTTAATGC

>g3485.t2 Gene=g3485 Length=117
MEQVPALQIDGHTLVESLAIMQYLEETRPQRPLMPQDFHKRAKVRELCEIIASGIQPLQN
LIVLIHVGEEKKKEWAQHWITRGFRAVEKLLSTSAGKYCVGDEITLADCCLIPQVFN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g3485.t2 CDD cd03191 GST_C_Zeta 39 117 0.0000000
8 g3485.t2 Gene3D G3DSA:3.40.30.10 Glutaredoxin 1 39 0.0000000
7 g3485.t2 Gene3D G3DSA:1.20.1050.10 - 40 117 0.0000000
3 g3485.t2 PANTHER PTHR42673:SF4 MALEYLACETOACETATE ISOMERASE 1 117 0.0000000
4 g3485.t2 PANTHER PTHR42673 MALEYLACETOACETATE ISOMERASE 1 117 0.0000000
1 g3485.t2 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 32 0.0000009
2 g3485.t2 Pfam PF14497 Glutathione S-transferase, C-terminal domain 69 111 0.0000016
10 g3485.t2 ProSiteProfiles PS50404 Soluble glutathione S-transferase N-terminal domain profile. 1 32 13.9650000
9 g3485.t2 ProSiteProfiles PS50405 Soluble glutathione S-transferase C-terminal domain profile. 37 117 17.6550000
12 g3485.t2 SFLD SFLDG00358 Main (cytGST) 2 115 0.0000000
13 g3485.t2 SFLD SFLDS00019 Glutathione Transferase (cytosolic) 2 115 0.0000000
5 g3485.t2 SUPERFAMILY SSF52833 Thioredoxin-like 2 41 0.0000000
6 g3485.t2 SUPERFAMILY SSF47616 GST C-terminal domain-like 33 116 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006749 glutathione metabolic process BP
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values