General information for g3506.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aspartate aminotransferase, cytoplasmic.
Parent gene
- The parent gene g3506 is located on chr_3: 26058947..26060274 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3506 | g3506.t1 | TTS | g3506.t1 | 26058902 | 26058902 |
| chr_3 | g3506 | g3506.t1 | isoform | g3506.t1 | 26058947 | 26060274 |
| chr_3 | g3506 | g3506.t1 | exon | g3506.t1.exon1 | 26058947 | 26060100 |
| chr_3 | g3506 | g3506.t1 | cds | g3506.t1.CDS1 | 26058947 | 26060100 |
| chr_3 | g3506 | g3506.t1 | exon | g3506.t1.exon2 | 26060157 | 26060274 |
| chr_3 | g3506 | g3506.t1 | cds | g3506.t1.CDS2 | 26060157 | 26060274 |
| chr_3 | g3506 | g3506.t1 | TSS | g3506.t1 | 26060325 | 26060325 |
Sequences
>g3506.t1 Gene=g3506 Length=1272
ATGAAGAAATCAAGTGTTTTTGAAAATGTTGAACCTGGACATCCAGTTGAAATGAATTTG
TTGATTAAACGATATATGGAAGATAAAAATGAAAACAAAGTTAATTTAAGCATAGGCGTC
TACAGGACAGAAGAAGGAAAGTCTTATGTTCTGCCTTTTGTTAAACAAGTTGAAAAAGAA
ATTGTGAATGATCCAAATTTGAATTATGATTATCAGCCAATACTTGGTACTGATAGTTTC
TTCAATATTGCAACACAACTGCTTTTAGGTGAAGATTCCATTCACATTAGGAACAAAAAT
GCTTTTGGTTTACAAGCATTGAGTGGAACTGGTGGACTAAGAAGTGGTGCAGAATTTCTT
GCACGAATTATGGGTTACACGACTTTTTATTATTCAGATCCATCTTGGGAAAATCATCCA
AACATTTTCAATGCAGCTGGCTTTACAAATGAGAAAACATATAGATATTTTGATAGAAAA
ACCTTTGGCCTTGATTTTGATGGAATGATTGAAGATTTACAAAACGCACCTGAAAAAGCT
GTAATTATTTTGCAAATTTGTGGTCATAATCCATGTGCAGTTGATCCTACAAAAGAACAG
TGGATGAAAATTGCAGATGTAATTGAGGAGAAAAAACTTTTTCCATTTTTTGATGCTGCT
TATCATGGCTTTGGTACTGGTGATCTTGACGAAGATGTTTTTCCAGTACGTTATTTTGCT
GATCGCAGAATTGAATTTTTCTGTTCACAATCATTTGCCAAAAATTTTGGAATTTATAAC
ATTCGTTGTGGTGCTTTGACTGTTTTTACTAACGATCCTTCAAAAATTTCTGCAATTTTA
TCACAAATGACTTTACGAATTTATTTTCTTTATGAAACTCCACCAGCGTGTGGCCCAAGG
ATAGTTTCGAGAATTCTTCAAAATGCTAATTTGAAGAAACAATGGATTGATACATTAAAA
ATTATGACAGCAAGAATAACAAGAATGAGACAAAAGTTTCAAGATGAAATGATTCGATTA
AAGACTCCAGGTAAATGGGATTACATAACTAAACATCGAGGTATGTTTGCTTTTACAGGT
ATTACACCTGAACAAGCTGAAATTTTAGTTGATAAATATCACATTTATGTATTGAAATGT
GGACGAATTAATATTTGTGGAATAACTGATGAAAATCTTTCCTATGTTACAAAATCAATT
CATGAAGTTGTCTCAATGACAGCTTCAAAAGTCAATGACATAGTTGAGCATGAGAAAATA
ATTCAGTATTAA
>g3506.t1 Gene=g3506 Length=423
MKKSSVFENVEPGHPVEMNLLIKRYMEDKNENKVNLSIGVYRTEEGKSYVLPFVKQVEKE
IVNDPNLNYDYQPILGTDSFFNIATQLLLGEDSIHIRNKNAFGLQALSGTGGLRSGAEFL
ARIMGYTTFYYSDPSWENHPNIFNAAGFTNEKTYRYFDRKTFGLDFDGMIEDLQNAPEKA
VIILQICGHNPCAVDPTKEQWMKIADVIEEKKLFPFFDAAYHGFGTGDLDEDVFPVRYFA
DRRIEFFCSQSFAKNFGIYNIRCGALTVFTNDPSKISAILSQMTLRIYFLYETPPACGPR
IVSRILQNANLKKQWIDTLKIMTARITRMRQKFQDEMIRLKTPGKWDYITKHRGMFAFTG
ITPEQAEILVDKYHIYVLKCGRINICGITDENLSYVTKSIHEVVSMTASKVNDIVEHEKI
IQY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g3506.t1 | CDD | cd00609 | AAT_like | 34 | 392 | 0 |
| 8 | g3506.t1 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 23 | 401 | 0 |
| 9 | g3506.t1 | Gene3D | G3DSA:3.40.640.10 | - | 50 | 323 | 0 |
| 2 | g3506.t1 | PANTHER | PTHR11879 | ASPARTATE AMINOTRANSFERASE | 2 | 404 | 0 |
| 4 | g3506.t1 | PRINTS | PR00799 | Aspartate aminotransferase signature | 182 | 201 | 0 |
| 6 | g3506.t1 | PRINTS | PR00799 | Aspartate aminotransferase signature | 213 | 225 | 0 |
| 5 | g3506.t1 | PRINTS | PR00799 | Aspartate aminotransferase signature | 281 | 306 | 0 |
| 3 | g3506.t1 | PRINTS | PR00799 | Aspartate aminotransferase signature | 349 | 367 | 0 |
| 1 | g3506.t1 | Pfam | PF00155 | Aminotransferase class I and II | 32 | 400 | 0 |
| 7 | g3506.t1 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 5 | 404 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009058 | biosynthetic process | BP |
| GO:0006520 | cellular amino acid metabolic process | BP |
| GO:0008483 | transaminase activity | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
- This transcript has been annotated with K14455 (aspartate aminotransferase, mitochondrial)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
