General information for g351.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1.
Parent gene
- The parent gene g351 is located on chr_3: 2818910..2822934 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g351 | g351.t1 | TSS | g351.t1 | 2818853 | 2818853 |
| chr_3 | g351 | g351.t1 | isoform | g351.t1 | 2818910 | 2820729 |
| chr_3 | g351 | g351.t1 | exon | g351.t1.exon1 | 2818910 | 2818982 |
| chr_3 | g351 | g351.t1 | cds | g351.t1.CDS1 | 2818910 | 2818982 |
| chr_3 | g351 | g351.t1 | exon | g351.t1.exon2 | 2819060 | 2819454 |
| chr_3 | g351 | g351.t1 | cds | g351.t1.CDS2 | 2819060 | 2819454 |
| chr_3 | g351 | g351.t1 | exon | g351.t1.exon3 | 2819542 | 2819813 |
| chr_3 | g351 | g351.t1 | cds | g351.t1.CDS3 | 2819542 | 2819813 |
| chr_3 | g351 | g351.t1 | exon | g351.t1.exon4 | 2820078 | 2820729 |
| chr_3 | g351 | g351.t1 | cds | g351.t1.CDS4 | 2820078 | 2820729 |
| chr_3 | g351 | g351.t1 | TTS | g351.t1 | NA | NA |
Sequences
>g351.t1 Gene=g351 Length=1392
ATGACTAACAAAGTGATGTTAATTGCGTGCGGTTCTTATAATCCCGTAACGCCAATGCAT
CTAAGAATGTTTGAAATTGCCAATGATCATTTTACACAATTGGGTACAACTGAAGTAGTC
GGAGGCATTGTATCGCCTGTGCATGATTTATATGGAAAGAAAGGTCTTGCTTCACAAACT
CACAGAATTGCAATGCTCAAATTAGCTTTAAAAACTTCCAACTGGATTCGCGTTTCTGAA
TGGGAGACACAACAAGAAGGATGGACGAGAACTAGAAATACTCTGCAATATCATCAAAAT
TATCTCAACTCAATTATCCGTGATTTAAATGGCATGAATTCGTCTAATTTGCCCAGTTGG
GTTCCAGAAAATATACGTCAAATTAAGGAGCCAGTACAATTGAAATTACTTTGTGGTGCT
GATTTATTGGAATCATTTGCTACGCCTGGCTTATGGGAGAAAGAAGATCTTGAGGCGATA
CTTGGTCAACATGGAATTGTGGTTATTTCACGTAACGGCTCAGATGTTGAGCGCTTTATC
TTTGAATCAGACCTTCTAAGTCAATATCGACCGAATATCAATATAGTTACAAATTGGATT
GCGAATGAAGTGTCATCTACACTAGCTCGACGCTTCATCAGTCGAGGACTTTCTGTGAAA
TACATAATTGATGATTATGTAATTGAATACATCAACAAACATGGACTTTATCGCACATTA
ACGACGACTGCTGATGAAACAAGTAAATTCATTTTACCTCCAACATCAACAACAACCACG
GAAATTAGTGTGATCGATCTAACACCTATATCACCAGAAAGTGAATCTTCGACTTTTAAT
GAGAGCTATGTAAAGAAGCAAAACGAAAAGAATGAAAGTTCAGTAGTGGAAGAATATGAA
AGTATGGATGAAACAGATTTTCCGCCGCCACCACCACCAATTGCATCAACCAAATCGAGC
TTAACTGTTGACTACATAACTGGCAGTTCAAGTTCATTACAGAAAGTATTTTGCTGTGCA
TCGAGTGATGGAACAGCTATTCGACTAATGCGACCAGGAAGTGCTGTTCAAGTACATGAT
GATGAAAAGGAAGATAATGATAAAAGTGATAAGGTCAGTGAAAATGAACAATATGATGCA
CAAACACATCCTATAAATACTCCGGACGATGATTATGGAGCAGCCGATGACACACCAACA
CCTTCACCTCGCTCACCTGAGCAAATTGAAATAATTGCACCAGATGAAGATCAAACTGAC
TCTGAATCGCTTAATGCACCAATTTCTAAAGCACACGGACGTTTTAGTCCAAAAAGTTAT
GATGAAATGATTAAATTTGTCTTCACAGAGCACGGCATAAGGGTTATTTCTGATAAAGAA
TATGTCGTTTAA
>g351.t1 Gene=g351 Length=463
MTNKVMLIACGSYNPVTPMHLRMFEIANDHFTQLGTTEVVGGIVSPVHDLYGKKGLASQT
HRIAMLKLALKTSNWIRVSEWETQQEGWTRTRNTLQYHQNYLNSIIRDLNGMNSSNLPSW
VPENIRQIKEPVQLKLLCGADLLESFATPGLWEKEDLEAILGQHGIVVISRNGSDVERFI
FESDLLSQYRPNINIVTNWIANEVSSTLARRFISRGLSVKYIIDDYVIEYINKHGLYRTL
TTTADETSKFILPPTSTTTTEISVIDLTPISPESESSTFNESYVKKQNEKNESSVVEEYE
SMDETDFPPPPPPIASTKSSLTVDYITGSSSSLQKVFCCASSDGTAIRLMRPGSAVQVHD
DEKEDNDKSDKVSENEQYDAQTHPINTPDDDYGAADDTPTPSPRSPEQIEIIAPDEDQTD
SESLNAPISKAHGRFSPKSYDEMIKFVFTEHGIRVISDKEYVV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g351.t1 | CDD | cd09286 | NMNAT_Eukarya | 5 | 237 | 1.35557E-113 |
| 7 | g351.t1 | Gene3D | G3DSA:3.40.50.620 | HUPs | 1 | 237 | 9.8E-81 |
| 6 | g351.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 276 | 311 | - |
| 5 | g351.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 351 | 430 | - |
| 4 | g351.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 355 | 377 | - |
| 2 | g351.t1 | PANTHER | PTHR12039 | NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE | 3 | 243 | 3.7E-93 |
| 1 | g351.t1 | Pfam | PF01467 | Cytidylyltransferase-like | 8 | 211 | 1.1E-26 |
| 3 | g351.t1 | SUPERFAMILY | SSF52374 | Nucleotidylyl transferase | 5 | 240 | 2.65E-52 |
| 8 | g351.t1 | TIGRFAM | TIGR00482 | TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase | 8 | 237 | 4.3E-44 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009058 | biosynthetic process | BP |
| GO:0016779 | nucleotidyltransferase activity | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0009435 | NAD biosynthetic process | BP |
KEGG
Orthology
- This transcript has been annotated with K06210 (nicotinamide mononucleotide adenylyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
