General information for g3702.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Wolframin.
Parent gene
- The parent gene g3702 is located on chr_3: 27558179..27558888 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g3702 | g3702.t1 | TTS | g3702.t1 | 27555975 | 27555975 |
| chr_3 | g3702 | g3702.t1 | isoform | g3702.t1 | 27556092 | 27558888 |
| chr_3 | g3702 | g3702.t1 | exon | g3702.t1.exon1 | 27556092 | 27556494 |
| chr_3 | g3702 | g3702.t1 | cds | g3702.t1.CDS1 | 27556092 | 27556494 |
| chr_3 | g3702 | g3702.t1 | exon | g3702.t1.exon2 | 27556557 | 27558588 |
| chr_3 | g3702 | g3702.t1 | cds | g3702.t1.CDS2 | 27556557 | 27558588 |
| chr_3 | g3702 | g3702.t1 | exon | g3702.t1.exon3 | 27558654 | 27558727 |
| chr_3 | g3702 | g3702.t1 | cds | g3702.t1.CDS3 | 27558654 | 27558727 |
| chr_3 | g3702 | g3702.t1 | exon | g3702.t1.exon4 | 27558794 | 27558888 |
| chr_3 | g3702 | g3702.t1 | cds | g3702.t1.CDS4 | 27558794 | 27558888 |
| chr_3 | g3702 | g3702.t1 | TSS | g3702.t1 | 27558967 | 27558967 |
Sequences
>g3702.t1 Gene=g3702 Length=2604
ATGGCTAATTGGTTAAATGGTGCAAACAATCAAGATAAATCAAAGCAACGCAAACGATGG
GAAATAGAAGACAAGAAATTGCTTAAAAACTTAAGAATGAAACTGGCAGATGATGGAAAC
AGTGATTGTCAATTTGAAGCTGCAAAAATGCTATTGGATGACACAGATGATCTCGATTCA
TCTTGTCAAGTTCAGGGAATTAATTACCTCAAAAAGGCAGCATCGCAAGGTCATGAAATG
GCGCTTGAATTATTAGGAGCATGCTATCGAACAAGACGAGGTATAAATTCAAGTAATGAA
AGTGAGATCAAAGAATTTTTGTCTCTTACACCAGCTGAGAGAACGGCTCGACATGCAGCT
CATGAACTTTTCAATAGTCTATGCAATGGAAATGAATATGTTACGGTTGAACAATTAGAA
AAACGAATGAGAGAAATTTATAAATTACAAAAGAAAAAGAAGAAACATGATGATGGAAGA
GTATATGATAATGAAGAAATTTTAGACCAAGAGGAAATAGAAGAAGCCAATATTAGCAGT
AGCAACAAAACGTCTTCATCGTCCTTTTATATTAGAAAACAAAGACGTTTAAATCATGAC
GAAAGTCATATTTCTAAAGAAAATTTATTGGTAGCTGCTGATAATTACAGTCATGGAGAA
TTGCCTCAAGTCAATAATGCATTGACACTCTCAATTCCTCATCCTCATGCACTTCAACAC
GTTCCATATTTTCATCGACCATTTTTTCATCCTGCAATGTTCTTTTCACTGCTCTATCAT
CGATTCATTAAAATATTTTCATCATTTCCAAGTGATCTATTTAATAAGTATCAAATTCTC
TTCGCATTGCTCATGTACGCATTACTTTCAACAAACACAAATCTTTTGATTTCACTTCCA
ACGGTAGTATATTACATTTCACTCTTTATCATGGTAGTTGCAAGTTTCAAAATGCTAAAA
AGCAAACATGAATTCATAGATTTTCGCATATGGTCAGGATTATTTCTTTCATACAATGAG
AATGTTTATGCCGACAATTCAGAAAATCAATTTCTTCGGAATAATTTAAAACCTTACTTT
TGGTTTTTCCTTGCATTTGCGGTAAATTTGATGATTTATCCGCTAATTTCGGATCAATGG
CTTCCAAATTCTGAAATTACTGTGGTATCATTGACATTAATGTTTCTTACACTTGTATGT
TTCATTAATACATCATCGCATTCGGGTCTTCCTGACTTCATAACATTAATGTCATTTGCT
GTTAATATAGTAGCAAAATATCCGGACAGTGTTGTGAGTAGCAAATGGAGATTTTTGGAT
TTGAAAATTCCTGAAATTCCTAGTTTTATGATTGGTAGTGGAATAGAATTTTCAATGAAT
TGTCGTGGTATGTTGTATATCGTGATAATCATATTTATGTTAATTCTTGCACGACGAAGA
AATTGGCATGGAATTTATCAATTTTTGATTCCTCATTGCGTAACATTAGCATGGATGCAA
ATTAGTTTAATCAACTCACAATCGGCAACAACTTTTGGATTAATGCGATCCTGTTTAGGA
CTAGCTGGAATTATTTTCTTTTTACCCGCATTTGGCTTAGCTACTTTGTTTATACCAGTC
TTTGCTGCAGTTGAATGGATTTCAGTTAAAGATTCAACCAACAAATTATTCATAACAATA
TCAACAAGTCTTATAGCAATATTAGGTTCTTGTTTTATGGCAATATCACATCGTACTGGG
AAATATGTTACATATGTTCAAATACTTTTATGTGTATGTGCATGCTTTTTCTTATGTACA
CCCTACATGAAAATGAATGACGAAAATCCTTATGCTTCCTATTTACAAGAAGCCAAAGTC
ATTTCAAATGTTGACATTGAAGAGACCACAATTGATTGGAAAACATTTTATAAATATTGC
TTAGAATCTTCGGATGGAAATAAAATAAATTTGCAAATGAGATGTAGACATTTAGATGGA
ATAAAAATTAACTGGGATGGAATTGTAAGTGATGTAGAAATATCACAAATACGAAACTGG
AGAAAAGATTTTTTAGAAAGATTCTTACCTGATTTCATATCAAAACACATCATATGCTAT
TTTGGAGAAATAAATAAAGCAGAATGCTTCAATAATGAAAACTGTGAAATTAAAGAATTC
ATTGAAAATCAAAAGCAATGTAATCTTGATAAATGGAATATTTATGAATATGCGATAACA
GTAAATATTCAATCAAAAAGTTCAGGATTGCTCAATTATAATACGAAACAAGATTCAAAA
GTTGTACTAAAAGCTCATCATATATTTGGAAATTTCACAACACGACTCAATTCGTCTGAC
AAAATTTGGTTCAAAGGAGCTTTAAAAACTTTTCCATCATCATCACATAATCATGAAATA
AGCGATCTCTTAGCATGTAAAAATGATAAACATACTCGAATTGAAGTTAATTCTATTGGA
TGTCTTCAATGTTTAGATAAAAATCTTTTGCCTGTCACTCAAAATTCAATGTTTAACATA
GATAATCAGCCGTTAGAAAGCCTTAGGCGAGGATTTAAGTATTTGTTAAATAGTTTATTT
TATCCCATGATCACTTTCAAATAA
>g3702.t1 Gene=g3702 Length=867
MANWLNGANNQDKSKQRKRWEIEDKKLLKNLRMKLADDGNSDCQFEAAKMLLDDTDDLDS
SCQVQGINYLKKAASQGHEMALELLGACYRTRRGINSSNESEIKEFLSLTPAERTARHAA
HELFNSLCNGNEYVTVEQLEKRMREIYKLQKKKKKHDDGRVYDNEEILDQEEIEEANISS
SNKTSSSSFYIRKQRRLNHDESHISKENLLVAADNYSHGELPQVNNALTLSIPHPHALQH
VPYFHRPFFHPAMFFSLLYHRFIKIFSSFPSDLFNKYQILFALLMYALLSTNTNLLISLP
TVVYYISLFIMVVASFKMLKSKHEFIDFRIWSGLFLSYNENVYADNSENQFLRNNLKPYF
WFFLAFAVNLMIYPLISDQWLPNSEITVVSLTLMFLTLVCFINTSSHSGLPDFITLMSFA
VNIVAKYPDSVVSSKWRFLDLKIPEIPSFMIGSGIEFSMNCRGMLYIVIIIFMLILARRR
NWHGIYQFLIPHCVTLAWMQISLINSQSATTFGLMRSCLGLAGIIFFLPAFGLATLFIPV
FAAVEWISVKDSTNKLFITISTSLIAILGSCFMAISHRTGKYVTYVQILLCVCACFFLCT
PYMKMNDENPYASYLQEAKVISNVDIEETTIDWKTFYKYCLESSDGNKINLQMRCRHLDG
IKINWDGIVSDVEISQIRNWRKDFLERFLPDFISKHIICYFGEINKAECFNNENCEIKEF
IENQKQCNLDKWNIYEYAITVNIQSKSSGLLNYNTKQDSKVVLKAHHIFGNFTTRLNSSD
KIWFKGALKTFPSSSHNHEISDLLACKNDKHTRIEVNSIGCLQCLDKNLLPVTQNSMFNI
DNQPLESLRRGFKYLLNSLFYPMITFK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 24 | g3702.t1 | Gene3D | G3DSA:1.25.40.10 | - | 12 | 195 | 1.2E-7 |
| 1 | g3702.t1 | PANTHER | PTHR13098 | WOLFRAMIN | 11 | 867 | 2.3E-168 |
| 2 | g3702.t1 | PANTHER | PTHR13098:SF3 | WOLFRAMIN | 11 | 867 | 2.3E-168 |
| 13 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 67 | 88 | 6.3E-91 |
| 6 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 93 | 106 | 6.3E-91 |
| 14 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 110 | 128 | 6.3E-91 |
| 11 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 204 | 222 | 6.3E-91 |
| 3 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 235 | 252 | 6.3E-91 |
| 10 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 354 | 374 | 6.3E-91 |
| 8 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 374 | 394 | 6.3E-91 |
| 9 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 436 | 452 | 6.3E-91 |
| 5 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 482 | 500 | 6.3E-91 |
| 7 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 510 | 529 | 6.3E-91 |
| 4 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 647 | 667 | 6.3E-91 |
| 12 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 727 | 743 | 6.3E-91 |
| 15 | g3702.t1 | PRINTS | PR02060 | Wolframin family signature | 763 | 784 | 6.3E-91 |
| 35 | g3702.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 247 | - |
| 43 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 248 | 267 | - |
| 27 | g3702.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 268 | 278 | - |
| 41 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 279 | 297 | - |
| 34 | g3702.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 298 | 302 | - |
| 46 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 303 | 319 | - |
| 26 | g3702.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 320 | 358 | - |
| 42 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 359 | 376 | - |
| 33 | g3702.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 377 | 381 | - |
| 39 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 382 | 402 | - |
| 29 | g3702.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 403 | 408 | - |
| 38 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 409 | 427 | - |
| 32 | g3702.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 428 | 456 | - |
| 47 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 457 | 477 | - |
| 25 | g3702.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 478 | 483 | - |
| 44 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 484 | 501 | - |
| 36 | g3702.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 502 | 520 | - |
| 45 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 521 | 544 | - |
| 30 | g3702.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 545 | 555 | - |
| 40 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 556 | 576 | - |
| 31 | g3702.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 577 | 581 | - |
| 37 | g3702.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 582 | 603 | - |
| 28 | g3702.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 604 | 867 | - |
| 22 | g3702.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 294 | 316 | - |
| 21 | g3702.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 359 | 376 | - |
| 20 | g3702.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 386 | 405 | - |
| 18 | g3702.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 463 | 480 | - |
| 16 | g3702.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 484 | 506 | - |
| 17 | g3702.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 519 | 541 | - |
| 23 | g3702.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 556 | 575 | - |
| 19 | g3702.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 582 | 604 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K14020 (wolfamin)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
