Gene loci information

Transcript annotation

  • This transcript has been annotated as Wolframin.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3702 g3702.t16 isoform g3702.t16 27557073 27558888
chr_3 g3702 g3702.t16 exon g3702.t16.exon1 27557073 27558588
chr_3 g3702 g3702.t16 cds g3702.t16.CDS1 27557075 27558588
chr_3 g3702 g3702.t16 exon g3702.t16.exon2 27558654 27558888
chr_3 g3702 g3702.t16 cds g3702.t16.CDS2 27558654 27558726
chr_3 g3702 g3702.t16 TSS g3702.t16 27558967 27558967
chr_3 g3702 g3702.t16 TTS g3702.t16 NA NA

Sequences

>g3702.t16 Gene=g3702 Length=1751
ATGGCTAATTGGTTAAATGGTGCAAACAATCAAGATAAATCAAAGCAACGCAAACGATGG
GAAATAGAAGACAAGAAATTGCTTAAAAACTTAAGGTGAATTAGTTATTTTCAATATTTT
TACAACAACAGTTCAACATAAATTGTAATTTTTCTTGGAAGAATGAAACTGGCAGATGAT
GGAAACAGTGATTGTCAATTTGAAGCTGCAAAAATGCTATTGGATGACACAGATGATCTC
GATTCATCTTGTCAAGTTCAGGGAATTAATTACCTCAAAAAGGCAGCATCGCAAGGTCAT
GAAATGGCGCTTGAATTATTAGGAGCATGCTATCGAACAAGACGAGGTATAAATTCAAGT
AATGAAAGTGAGATCAAAGAATTTTTGTCTCTTACACCAGCTGAGAGAACGGCTCGACAT
GCAGCTCATGAACTTTTCAATAGTCTATGCAATGGAAATGAATATGTTACGGTTGAACAA
TTAGAAAAACGAATGAGAGAAATTTATAAATTACAAAAGAAAAAGAAGAAACATGATGAT
GGAAGAGTATATGATAATGAAGAAATTTTAGACCAAGAGGAAATAGAAGAAGCCAATATT
AGCAGTAGCAACAAAACGTCTTCATCGTCCTTTTATATTAGAAAACAAAGACGTTTAAAT
CATGACGAAAGTCATATTTCTAAAGAAAATTTATTGGTAGCTGCTGATAATTACAGTCAT
GGAGAATTGCCTCAAGTCAATAATGCATTGACACTCTCAATTCCTCATCCTCATGCACTT
CAACACGTTCCATATTTTCATCGACCATTTTTTCATCCTGCAATGTTCTTTTCACTGCTC
TATCATCGATTCATTAAAATATTTTCATCATTTCCAAGTGATCTATTTAATAAGTATCAA
ATTCTCTTCGCATTGCTCATGTACGCATTACTTTCAACAAACACAAATCTTTTGATTTCA
CTTCCAACGGTAGTATATTACATTTCACTCTTTATCATGGTAGTTGCAAGTTTCAAAATG
CTAAAAAGCAAACATGAATTCATAGATTTTCGCATATGGTCAGGATTATTTCTTTCATAC
AATGAGAATGTTTATGCCGACAATTCAGAAAATCAATTTCTTCGGAATAATTTAAAACCT
TACTTTTGGTTTTTCCTTGCATTTGCGGTAAATTTGATGATTTATCCGCTAATTTCGGAT
CAATGGCTTCCAAATTCTGAAATTACTGTGGTATCATTGACATTAATGTTTCTTACACTT
GTATGTTTCATTAATACATCATCGCATTCGGGTCTTCCTGACTTCATAACATTAATGTCA
TTTGCTGTTAATATAGTAGCAAAATATCCGGACAGTGTTGTGAGTAGCAAATGGAGATTT
TTGGATTTGAAAATTCCTGAAATTCCTAGTTTTATGATTGGTAGTGGAATAGAATTTTCA
ATGAATTGTCGTGGTATGTTGTATATCGTGATAATCATATTTATGTTAATTCTTGCACGA
CGAAGAAATTGGCATGGAATTTATCAATTTTTGATTCCTCATTGCGTAACATTAGCATGG
ATGCAAATTAGTTTAATCAACTCACAATCGGCAACAACTTTTGGATTAATGCGATCCTGT
TTAGGACTAGCTGGAATTATTTTCTTTTTACCCGCATTTGGCTTAGCTACTTTGTTTATA
CCAGTCTTTGCTGCAGTTGAATGGATTTCAGTTAAAGATTCAACCAACAAATTATTCATA
ACAATATCAAC

>g3702.t16 Gene=g3702 Length=529
MKLADDGNSDCQFEAAKMLLDDTDDLDSSCQVQGINYLKKAASQGHEMALELLGACYRTR
RGINSSNESEIKEFLSLTPAERTARHAAHELFNSLCNGNEYVTVEQLEKRMREIYKLQKK
KKKHDDGRVYDNEEILDQEEIEEANISSSNKTSSSSFYIRKQRRLNHDESHISKENLLVA
ADNYSHGELPQVNNALTLSIPHPHALQHVPYFHRPFFHPAMFFSLLYHRFIKIFSSFPSD
LFNKYQILFALLMYALLSTNTNLLISLPTVVYYISLFIMVVASFKMLKSKHEFIDFRIWS
GLFLSYNENVYADNSENQFLRNNLKPYFWFFLAFAVNLMIYPLISDQWLPNSEITVVSLT
LMFLTLVCFINTSSHSGLPDFITLMSFAVNIVAKYPDSVVSSKWRFLDLKIPEIPSFMIG
SGIEFSMNCRGMLYIVIIIFMLILARRRNWHGIYQFLIPHCVTLAWMQISLINSQSATTF
GLMRSCLGLAGIIFFLPAFGLATLFIPVFAAVEWISVKDSTNKLFITIS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
19 g3702.t16 Gene3D G3DSA:1.25.40.10 - 1 176 1.7E-8
1 g3702.t16 PANTHER PTHR13098 WOLFRAMIN 2 527 2.0E-113
2 g3702.t16 PANTHER PTHR13098:SF3 WOLFRAMIN 2 527 2.0E-113
9 g3702.t16 PRINTS PR02060 Wolframin family signature 35 56 1.0E-70
11 g3702.t16 PRINTS PR02060 Wolframin family signature 61 74 1.0E-70
6 g3702.t16 PRINTS PR02060 Wolframin family signature 78 96 1.0E-70
4 g3702.t16 PRINTS PR02060 Wolframin family signature 172 190 1.0E-70
3 g3702.t16 PRINTS PR02060 Wolframin family signature 203 220 1.0E-70
10 g3702.t16 PRINTS PR02060 Wolframin family signature 322 342 1.0E-70
8 g3702.t16 PRINTS PR02060 Wolframin family signature 342 362 1.0E-70
7 g3702.t16 PRINTS PR02060 Wolframin family signature 404 420 1.0E-70
5 g3702.t16 PRINTS PR02060 Wolframin family signature 450 468 1.0E-70
12 g3702.t16 PRINTS PR02060 Wolframin family signature 478 497 1.0E-70
26 g3702.t16 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 215 -
33 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 216 235 -
21 g3702.t16 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 236 246 -
37 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 247 265 -
27 g3702.t16 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 266 270 -
32 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 271 287 -
24 g3702.t16 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 288 326 -
34 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 327 344 -
29 g3702.t16 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 345 349 -
38 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 350 370 -
20 g3702.t16 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 371 376 -
31 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 377 395 -
28 g3702.t16 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 396 424 -
35 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 425 445 -
23 g3702.t16 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 446 451 -
30 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 452 472 -
25 g3702.t16 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 473 491 -
36 g3702.t16 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 492 515 -
22 g3702.t16 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 516 529 -
17 g3702.t16 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 262 284 -
14 g3702.t16 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 327 344 -
18 g3702.t16 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 356 378 -
16 g3702.t16 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 423 445 -
15 g3702.t16 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 450 472 -
13 g3702.t16 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 487 509 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values