Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Wolframin.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3702 g3702.t17 isoform g3702.t17 27558179 27558888
chr_3 g3702 g3702.t17 exon g3702.t17.exon1 27558179 27558588
chr_3 g3702 g3702.t17 cds g3702.t17.CDS1 27558179 27558588
chr_3 g3702 g3702.t17 exon g3702.t17.exon2 27558654 27558727
chr_3 g3702 g3702.t17 cds g3702.t17.CDS2 27558654 27558727
chr_3 g3702 g3702.t17 exon g3702.t17.exon3 27558794 27558888
chr_3 g3702 g3702.t17 cds g3702.t17.CDS3 27558794 27558888
chr_3 g3702 g3702.t17 TSS g3702.t17 27558967 27558967
chr_3 g3702 g3702.t17 TTS g3702.t17 NA NA

Sequences

>g3702.t17 Gene=g3702 Length=579
ATGGCTAATTGGTTAAATGGTGCAAACAATCAAGATAAATCAAAGCAACGCAAACGATGG
GAAATAGAAGACAAGAAATTGCTTAAAAACTTAAGAATGAAACTGGCAGATGATGGAAAC
AGTGATTGTCAATTTGAAGCTGCAAAAATGCTATTGGATGACACAGATGATCTCGATTCA
TCTTGTCAAGTTCAGGGAATTAATTACCTCAAAAAGGCAGCATCGCAAGGTCATGAAATG
GCGCTTGAATTATTAGGAGCATGCTATCGAACAAGACGAGGTATAAATTCAAGTAATGAA
AGTGAGATCAAAGAATTTTTGTCTCTTACACCAGCTGAGAGAACGGCTCGACATGCAGCT
CATGAACTTTTCAATAGTCTATGCAATGGAAATGAATATGTTACGGTTGAACAATTAGAA
AAACGAATGAGAGAAATTTATAAATTACAAAAGAAAAAGAAGAAACATGATGATGGAAGA
GTATATGATAATGAAGAAATTTTAGACCAAGAGGAAATAGAAGAAGCCAATATTAGCAGT
AGCAACAAAACGTCTTCATCGTCCTTTTATATTAGAAAA

>g3702.t17 Gene=g3702 Length=193
MANWLNGANNQDKSKQRKRWEIEDKKLLKNLRMKLADDGNSDCQFEAAKMLLDDTDDLDS
SCQVQGINYLKKAASQGHEMALELLGACYRTRRGINSSNESEIKEFLSLTPAERTARHAA
HELFNSLCNGNEYVTVEQLEKRMREIYKLQKKKKKHDDGRVYDNEEILDQEEIEEANISS
SNKTSSSSFYIRK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g3702.t17 Gene3D G3DSA:1.25.40.10 - 4 188 0
1 g3702.t17 PANTHER PTHR13098 WOLFRAMIN 11 168 0
2 g3702.t17 PANTHER PTHR13098:SF3 WOLFRAMIN 11 168 0
4 g3702.t17 PRINTS PR02060 Wolframin family signature 67 88 0
3 g3702.t17 PRINTS PR02060 Wolframin family signature 93 106 0
5 g3702.t17 PRINTS PR02060 Wolframin family signature 110 128 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values