Gene loci information

Transcript annotation

  • This transcript has been annotated as Serine/threonine-protein phosphatase 5.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3707 g3707.t1 TSS g3707.t1 27568731 27568731
chr_3 g3707 g3707.t1 isoform g3707.t1 27568802 27570764
chr_3 g3707 g3707.t1 exon g3707.t1.exon1 27568802 27568892
chr_3 g3707 g3707.t1 cds g3707.t1.CDS1 27568802 27568892
chr_3 g3707 g3707.t1 exon g3707.t1.exon2 27569257 27569874
chr_3 g3707 g3707.t1 cds g3707.t1.CDS2 27569257 27569874
chr_3 g3707 g3707.t1 exon g3707.t1.exon3 27569940 27570425
chr_3 g3707 g3707.t1 cds g3707.t1.CDS3 27569940 27570425
chr_3 g3707 g3707.t1 exon g3707.t1.exon4 27570487 27570764
chr_3 g3707 g3707.t1 cds g3707.t1.CDS4 27570487 27570764
chr_3 g3707 g3707.t1 TTS g3707.t1 27570813 27570813

Sequences

>g3707.t1 Gene=g3707 Length=1473
ATGGCAACTGAAGTCAAAAATGGAAGTCCAACTGCAGAGCAGATAGCAGAGGCTGATAAA
TATAAAGAACAAGCTAATGAATACTTCAAAAATAAAATATATGATAAGGCTATCGAGTTA
TATTCAAAGGCAATTGAGTTAGACCCAAATAATGCAGTTTATTATGCAAACAGATCACTT
GCAAATCTTCGAACAGAATTATTTGGATATGCACTTAACGATGCTGTTAAGGCTGTAAAG
GCTGATCCAGGATACTTAAAAGGATATTATCGTCGAGCGGCAGCACATATGTCTTTAGGA
AAATTCAAACTCGCACTTGCTGACTTTGAGATTGTAAGTAAGAGAAGACCAAACGATTCC
GATGCTAAAAAGAAATTCGTAGAGTGCAATAAGATTGTAAAAAAGATTGCATTCGAGAGA
GCGATTGCTGTTGATAGACCAGAAAAAACTCTGGCTGAAATGTATCAAAGTTTAGACTCG
ATCTCAATTGAAGATGATTATAATGGACCAAAATTAAAAGACGACGAAACAGTTACCATA
GAATTTATGAAAGAGCTAATGCAATGGTACAAAGATCAAAAGAAATTACACAAGAAGTTT
GCTTATAAAATTCTTTACGACATTGATTCCTATCTAAGGAAACAGCCTTCACTCGTTGAT
ATTTCAATTCCTGATGAAGGAAAATTTACGATTTGTGGAGATATTCATGGGCAATTTTAT
GATCTATTAAACATTTTTGAAAAAAATGGTCTTCCTTCCGAAACAAATCCTTATTTATTC
AATGGTGATTTTGTTGATCGTGGTTCGTTTAGTGTTGAATGTATTTTTACACTATTTGGT
TTTAAACTGCTATATCCAAATCATTTTTATATGAGCCGAGGAAATCATGAATCAGTAAAT
ATGAATCAAATGTATGGCTTTACTGGTGAAGTAACAGCAAAATATAATAGCACTATGGCT
GATATGTTCACGCAAGTTTTTAATTTCTTGCCACTATCACATGTGCTCAATAATAAAGTG
CTTGTATGTCACGGTGGCCTCTTTTCAAGTGATGATGTTATGCTCGATGATTTACGTAAA
ATTGAAAGAAATAGGCAACCTCCAGAGGAAGGTTTAATGTGTGAATTACTATGGTCAGAT
CCACAAGCTCAAAATGGTAGAGCTCCTTCAAAACGAGGTGTTGGTTGTCAGTTTGGTCCT
GATGTGACTGAAAATTTCTTAAAGAAAAATAATTTGGAGTATGTTGTAAGAAGCCATGAA
GTAAAAGACATGGGTTACGAAATTGCTCATGATGGAAAATGCATTACAGTATTTTCTGCA
CCAAATTATTGTGACACTATGGGAAATAAAGGTGCATATATAAATTTAAAAGGAAAAGAC
ATGAAACCATCATTTGAAGTGTTTGATGCAGTTCCACATCCAAACGTTAAACCAATGATG
TATGCTAATTCATTAATGAACTTGATAATGTAG

>g3707.t1 Gene=g3707 Length=490
MATEVKNGSPTAEQIAEADKYKEQANEYFKNKIYDKAIELYSKAIELDPNNAVYYANRSL
ANLRTELFGYALNDAVKAVKADPGYLKGYYRRAAAHMSLGKFKLALADFEIVSKRRPNDS
DAKKKFVECNKIVKKIAFERAIAVDRPEKTLAEMYQSLDSISIEDDYNGPKLKDDETVTI
EFMKELMQWYKDQKKLHKKFAYKILYDIDSYLRKQPSLVDISIPDEGKFTICGDIHGQFY
DLLNIFEKNGLPSETNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFYMSRGNHESVN
MNQMYGFTGEVTAKYNSTMADMFTQVFNFLPLSHVLNNKVLVCHGGLFSSDDVMLDDLRK
IERNRQPPEEGLMCELLWSDPQAQNGRAPSKRGVGCQFGPDVTENFLKKNNLEYVVRSHE
VKDMGYEIAHDGKCITVFSAPNYCDTMGNKGAYINLKGKDMKPSFEVFDAVPHPNVKPMM
YANSLMNLIM

Protein features from InterProScan

Transcript Database ID Name Start End E.value
18 g3707.t1 CDD cd07417 MPP_PP5_C 167 483 0.0000e+00
15 g3707.t1 Gene3D G3DSA:1.25.40.10 - 7 169 0.0000e+00
16 g3707.t1 Gene3D G3DSA:3.60.21.10 - 170 490 0.0000e+00
4 g3707.t1 PANTHER PTHR45668 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED 21 488 0.0000e+00
5 g3707.t1 PANTHER PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5 21 488 0.0000e+00
17 g3707.t1 PIRSF PIRSF033096 PPPtase_5 5 490 0.0000e+00
8 g3707.t1 PRINTS PR00114 Serine/threonine phosphatase family signature 228 255 0.0000e+00
6 g3707.t1 PRINTS PR00114 Serine/threonine phosphatase family signature 258 285 0.0000e+00
7 g3707.t1 PRINTS PR00114 Serine/threonine phosphatase family signature 291 315 0.0000e+00
12 g3707.t1 PRINTS PR00114 Serine/threonine phosphatase family signature 325 351 0.0000e+00
10 g3707.t1 PRINTS PR00114 Serine/threonine phosphatase family signature 355 382 0.0000e+00
9 g3707.t1 PRINTS PR00114 Serine/threonine phosphatase family signature 411 431 0.0000e+00
11 g3707.t1 PRINTS PR00114 Serine/threonine phosphatase family signature 433 449 0.0000e+00
2 g3707.t1 Pfam PF00515 Tetratricopeptide repeat 19 51 0.0000e+00
1 g3707.t1 Pfam PF08321 PPP5 TPR repeat region 128 220 0.0000e+00
3 g3707.t1 Pfam PF00149 Calcineurin-like phosphoesterase 228 422 0.0000e+00
24 g3707.t1 ProSiteProfiles PS50005 TPR repeat profile. 18 51 1.2567e+01
25 g3707.t1 ProSiteProfiles PS50293 TPR repeat region circular profile. 18 119 2.0680e+01
23 g3707.t1 ProSiteProfiles PS50005 TPR repeat profile. 86 119 7.4340e+00
21 g3707.t1 SMART SM00028 tpr_5 18 51 3.0000e-07
20 g3707.t1 SMART SM00028 tpr_5 52 85 1.2000e+02
19 g3707.t1 SMART SM00028 tpr_5 86 119 1.4000e-03
22 g3707.t1 SMART SM00156 pp2a_7 196 472 0.0000e+00
13 g3707.t1 SUPERFAMILY SSF48452 TPR-like 17 130 0.0000e+00
14 g3707.t1 SUPERFAMILY SSF56300 Metallo-dependent phosphatases 162 485 0.0000e+00

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016787 hydrolase activity MF
GO:0005515 protein binding MF
GO:0004721 phosphoprotein phosphatase activity MF
GO:0006470 protein dephosphorylation BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values