Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Dual specificity mitogen-activated protein kinase kinase 4.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3883 g3883.t2 TSS g3883.t2 28611026 28611026
chr_3 g3883 g3883.t2 isoform g3883.t2 28611269 28611757
chr_3 g3883 g3883.t2 exon g3883.t2.exon1 28611269 28611357
chr_3 g3883 g3883.t2 cds g3883.t2.CDS1 28611269 28611357
chr_3 g3883 g3883.t2 exon g3883.t2.exon2 28611485 28611564
chr_3 g3883 g3883.t2 cds g3883.t2.CDS2 28611485 28611564
chr_3 g3883 g3883.t2 exon g3883.t2.exon3 28611622 28611757
chr_3 g3883 g3883.t2 cds g3883.t2.CDS3 28611622 28611755
chr_3 g3883 g3883.t2 TTS g3883.t2 NA NA

Sequences

>g3883.t2 Gene=g3883 Length=305
ATGGATAACGACAGTAAAAAAGCACTTAAATTAGTTTTCCCGAGTCAATCAAGAACAGCC
CATAGGCCCCATCAATCGCTACCTACAAATCGTGATCGATTTCGTAATGCTCATTCGGAT
TCTGGAAAATTGCAATTTAGCAGTACTGAGATATATGATTTTACAGCAGACGATCTCTTA
GACCTTGGTGAAATCGGAAGAGGCGGTTTTGGAAGTGTTAATAAAATGATTTTTAAGAAA
ACAGAAAAAGTAATGGCAGTTAAAAGAATACGATGTTCTAATGTTGTTGATGAGAAGGAG
CAAAA

>g3883.t2 Gene=g3883 Length=101
MDNDSKKALKLVFPSQSRTAHRPHQSLPTNRDRFRNAHSDSGKLQFSSTEIYDFTADDLL
DLGEIGRGGFGSVNKMIFKKTEKVMAVKRIRCSNVVDEKEQ

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g3883.t2 Gene3D G3DSA:3.30.200.20 Phosphorylase Kinase; domain 1 37 101 9.7E-16
6 g3883.t2 MobiDBLite mobidb-lite consensus disorder prediction 1 41 -
5 g3883.t2 MobiDBLite mobidb-lite consensus disorder prediction 25 39 -
1 g3883.t2 PANTHER PTHR48013 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED 20 101 8.4E-21
2 g3883.t2 PANTHER PTHR48013:SF15 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 20 101 8.4E-21
4 g3883.t2 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 65 88 -
3 g3883.t2 SUPERFAMILY SSF56112 Protein kinase-like (PK-like) 41 99 6.39E-8

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values