Gene loci information

Transcript annotation

  • This transcript has been annotated as Cystathionine gamma-lyase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3934 g3934.t5 TSS g3934.t5 28989283 28989283
chr_3 g3934 g3934.t5 isoform g3934.t5 28989406 28991402
chr_3 g3934 g3934.t5 exon g3934.t5.exon1 28989406 28989413
chr_3 g3934 g3934.t5 cds g3934.t5.CDS1 28989406 28989413
chr_3 g3934 g3934.t5 exon g3934.t5.exon2 28990546 28990647
chr_3 g3934 g3934.t5 cds g3934.t5.CDS2 28990546 28990647
chr_3 g3934 g3934.t5 exon g3934.t5.exon3 28990727 28991293
chr_3 g3934 g3934.t5 cds g3934.t5.CDS3 28990727 28991293
chr_3 g3934 g3934.t5 exon g3934.t5.exon4 28991350 28991402
chr_3 g3934 g3934.t5 cds g3934.t5.CDS4 28991350 28991401
chr_3 g3934 g3934.t5 TTS g3934.t5 28992182 28992182

Sequences

>g3934.t5 Gene=g3934 Length=730
ATGTCCAACAGATTGACTTTTGGTGAAGAACTTGGATTTAAGAGGCAAAGTGAGGGGTTT
TCAACGAAAGCCATTCACTTGGGTCAAAAGCCCGAACAATGGAATAGCAGAGCTGTTGTG
CCTCCAATTTCATTGAGCACGACATTCAAACAAACAGCACCAGGCGTTCATTCGGGATTT
GAGTATAGTCGTTCAGGTAATCCAACTAGAAATGTCCTTGAAGCATGCCTCGCTGGTCTC
GACAATGCCAAATTCGCAGTAACATTTGCTAGTGGTCTTGGTACACAGACTGCCATCATC
AGCACACTTAAAACTGGCGATGGAATCATCACTGGTGATGATATATACGGCGGAACAAAT
CGATTGTTTCGTAATCTTGCCGCAAATATGGGAATTGAAGTTCAATTTGTTGATTTAACC
GATTTGAAAAACTTGGAGCAATCAATAAAACCAAATACAAAACTCGTATGGATGGAAACA
CCAACAAATCCGTGTATGAAAGTGATTGATATTAAAGGCGTTGCAGACATTGTTCATTCC
AAAACAAAAGCTTTCCTTGTTGTTGACAATACCTTCTTATCGGCTTACTTTCAACGTCCA
TTAGATTTGGGTGCTGATATTGTTATGTACAGTTTAACAAAATACATGAATGGTCATACT
GATGTAATTATGGGCAGCGCATCAACAAATAATGATGAATTGCATGAAAAACTCCGCTTT
TATCAAAATG

>g3934.t5 Gene=g3934 Length=243
MSNRLTFGEELGFKRQSEGFSTKAIHLGQKPEQWNSRAVVPPISLSTTFKQTAPGVHSGF
EYSRSGNPTRNVLEACLAGLDNAKFAVTFASGLGTQTAIISTLKTGDGIITGDDIYGGTN
RLFRNLAANMGIEVQFVDLTDLKNLEQSIKPNTKLVWMETPTNPCMKVIDIKGVADIVHS
KTKAFLVVDNTFLSAYFQRPLDLGADIVMYSLTKYMNGHTDVIMGSASTNNDELHEKLRF
YQN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g3934.t5 Coils Coil Coil 224 243 -
5 g3934.t5 Gene3D G3DSA:3.40.640.10 - 19 243 5.7E-81
2 g3934.t5 PANTHER PTHR11808:SF15 CYSTATHIONINE GAMMA-LYASE 15 243 3.8E-89
3 g3934.t5 PANTHER PTHR11808 TRANS-SULFURATION ENZYME FAMILY MEMBER 15 243 3.8E-89
1 g3934.t5 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 21 243 2.7E-77
4 g3934.t5 SUPERFAMILY SSF53383 PLP-dependent transferases 19 243 2.13E-58

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0019346 transsulfuration BP
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed