Gene loci information

Transcript annotation

  • This transcript has been annotated as 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g3991 g3991.t3 TTS g3991.t3 29399663 29399663
chr_3 g3991 g3991.t3 isoform g3991.t3 29399724 29400732
chr_3 g3991 g3991.t3 exon g3991.t3.exon1 29399724 29400322
chr_3 g3991 g3991.t3 cds g3991.t3.CDS1 29399724 29400322
chr_3 g3991 g3991.t3 exon g3991.t3.exon2 29400387 29400732
chr_3 g3991 g3991.t3 cds g3991.t3.CDS2 29400387 29400432
chr_3 g3991 g3991.t3 TSS g3991.t3 29400752 29400752

Sequences

>g3991.t3 Gene=g3991 Length=945
ATGTTTCGTAAATTAAATTTATTTAAAATTTATCGTACGTTTAATAAAAGACAATTATCA
TTGTCTATAAGATGCTGTAATAATTTTACTGAAGAATCTAAGGATTTTACTCATTTTGGT
TTTGAAACTGTCAAAACTGATGAAAAGACAGAAAAGGGTAGGAAAATTTATTTTTAATAA
AAAGTACCTATTTCAAATTATTACGTTTTTATTAAATTTTACAGTACATCAAGTTTTTAA
AGATGTTGCTGAAAAGTATGATTTAATGAATGATGCAATGTCAATGGGTATTCATCGATT
ATGGAAAGATATATTTCTAGAAAGACTCTATCCAACATTAGGAACTATGTTGCTGGTGGA
ACAGGAGATATTGCGTTCAGATATATTAACTATATCAACAATTTAAATAAATCAAATCAA
GATGCATATAGTAAAAAGAGCTCGGTTACAATTCTTGACATTAATCAGCATATGCTTAAT
GTAGGAATGGAAAGAGCTGAAAAACTTGGTCACATATCAAATGAGACGCTTGATGTTGAA
TGGGTGTGTGGAAATGCAGAAGAGTTGCCACTTGAAAGTGATCAATTTACAGCATATACA
ATTGCATTCGGAATTAGAAATGTAACACATATAGACAAAGCATTAAGAGAAGCCTATAGA
GTTCTTAAACCTGGTGGTCGTTTTATGTGTCTCGAATTTAGTCATATTGAAAATAATGAA
ACACTTCAATGGCTCTATGATCAATATTCTTTTCAAGTTATACCACCGATGGGACAAATT
TTAGCGAATCAATGGCAACCCTATCAATACTTGGTTGAAAGTATTAGAAAGTTCCCGAAA
AAGTTAGAATTCAAATCAATGATAGAAGAAGCTGGTTTTAAGCAAGTTACATATGAAAAT
TTAACTCTTGGAATATGTGCTATTCACTCCGGTTTCAAATTATAG

>g3991.t3 Gene=g3991 Length=214
MERYISRKTLSNIRNYVAGGTGDIAFRYINYINNLNKSNQDAYSKKSSVTILDINQHMLN
VGMERAEKLGHISNETLDVEWVCGNAEELPLESDQFTAYTIAFGIRNVTHIDKALREAYR
VLKPGGRFMCLEFSHIENNETLQWLYDQYSFQVIPPMGQILANQWQPYQYLVESIRKFPK
KLEFKSMIEEAGFKQVTYENLTLGICAIHSGFKL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g3991.t3 CDD cd02440 AdoMet_MTases 17 130 1.9073E-10
5 g3991.t3 Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39 12 214 6.6E-61
2 g3991.t3 PANTHER PTHR43591 METHYLTRANSFERASE 17 213 3.3E-60
3 g3991.t3 PANTHER PTHR43591:SF24 2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL 17 213 3.3E-60
1 g3991.t3 Pfam PF01209 ubiE/COQ5 methyltransferase family 17 213 6.5E-67
7 g3991.t3 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 120 134 -
8 g3991.t3 ProSiteProfiles PS51608 UbiE family SAM-binding methyltransferase profile. 1 213 70.79
4 g3991.t3 SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases 17 202 5.11E-28
9 g3991.t3 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 17 213 2.2E-59

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0008168 methyltransferase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values