General information for g431.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as NAD(P) transhydrogenase, mitochondrial.
Parent gene
- The parent gene g431 is located on chr_3: 3330635..3331830 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g431 | g431.t1 | isoform | g431.t1 | 3330425 | 3331830 |
| chr_3 | g431 | g431.t1 | exon | g431.t1.exon1 | 3330425 | 3330635 |
| chr_3 | g431 | g431.t1 | cds | g431.t1.CDS1 | 3330425 | 3330635 |
| chr_3 | g431 | g431.t1 | exon | g431.t1.exon2 | 3330713 | 3331830 |
| chr_3 | g431 | g431.t1 | cds | g431.t1.CDS2 | 3330713 | 3331830 |
| chr_3 | g431 | g431.t1 | TTS | g431.t1 | 3332403 | 3332403 |
| chr_3 | g431 | g431.t1 | TSS | g431.t1 | NA | NA |
Sequences
>g431.t1 Gene=g431 Length=1329
ATGGGAGCTGAATTTTTAACAATTAATATCAAAGAAGATGGTTCAACTGCTGGCGGTTAT
TCAAAGGAAAGTAGTGAATTTATTGAAGCTGAAATGGCTTTATTCGCAAAGCAGTGCAAA
GAAGTTGATGTTATTATTACAACAGCTTTGATTCCTGGCAAAAAAGCTCCAATTTTAATT
TTAGAAGATCATATTAAGAGCATGAAGCCAGCACGGGTTGTTCATATTGGTCTTACTGAT
CTTCCATCACGTTTACCAACACAAGCATCAACACTTTATGCCAATAATATCTCAAAACTT
CTTCTTTCAATGGGCGAGAAAAATCATTTTGATATTAATTTGAAAGATGATGTAGTTCGT
GGAAGTATTGTTGCACATAATGGTGAAGTAACTTGGCCACCACCCGAAATTGCAGTTTCA
GCTCAACCACAGCCGAGTGCAAAGAAGGAAGGTCAAGCAGTTGTCAAATCCGCACCAGCA
AATCCATTTAAAGACACAATGACAAGTGTATTAACATATACAACTGGACTTGGCACATTA
ATCACACTCGGTGCTGTCTCGCCTAATCCTGCATTTACAACTATGATGTCAACATTTGCA
TTATCAGGCATTGTCGGTTATCATACAGTTTGGGGAGTTATTCCGGCTTTGCATTCACCA
CTTATGTCATGCACAAACGCTATCTCAGGAATTACAGCAGTTGGTGGTTTACTCTTGATG
GGCGGTGGATATTTCCCAACAAATTCAATTGAATTTTTATCAGCAGGTGCTGCTTTAATT
TCATTTGTAAACATTTTCGGTGGATTCTTAGTCACACAAAGAATGTTAGACATGTTCAAA
CGTCCAACTGATCCACCAGAATATAATTATTTGTATGGAATTCCTGCTGCTGCATTTTTG
GGGGAATACGGTCTCGCTGCAATGAATGGACTCTCTGAAGTTAATCAAATTGCTTACCTT
GCTGCATCATTGTGCTGTGTTGGTGCATTGAGCGGATTATCATCACAAAAGACTGCTCGT
TTGGGTAATGCACTTGGAATGATTGGTGTCACAGGCGGCATTGCAGCAACTTTAGGAATT
TTGGCACCAACCCCAGAAGTTTTAGCTCAAATGGCAGGCTGTGCAGGTATCGGTGGTTTG
CTAGGTACAATCATTGCTAAGAGAATTCAAATTACTGATTTGCCTCAATTGGTTGCTGGA
TTCCATTCACTTGTCGGTATGGCAGCAGTTCTTACTTGCGTCGCTACTTACATGCATGAT
TTCCCTAATTTGGCAACTGATCCAGCGGCAAATGTCTNCTCTTTGACATTTTGTTTCATA
AATAAATAA
>g431.t1 Gene=g431 Length=442
MGAEFLTINIKEDGSTAGGYSKESSEFIEAEMALFAKQCKEVDVIITTALIPGKKAPILI
LEDHIKSMKPARVVHIGLTDLPSRLPTQASTLYANNISKLLLSMGEKNHFDINLKDDVVR
GSIVAHNGEVTWPPPEIAVSAQPQPSAKKEGQAVVKSAPANPFKDTMTSVLTYTTGLGTL
ITLGAVSPNPAFTTMMSTFALSGIVGYHTVWGVIPALHSPLMSCTNAISGITAVGGLLLM
GGGYFPTNSIEFLSAGAALISFVNIFGGFLVTQRMLDMFKRPTDPPEYNYLYGIPAAAFL
GEYGLAAMNGLSEVNQIAYLAASLCCVGALSGLSSQKTARLGNALGMIGVTGGIAATLGI
LAPTPEVLAQMAGCAGIGGLLGTIIAKRIQITDLPQLVAGFHSLVGMAAVLTCVATYMHD
FPNLATDPAANVXSLTFCFINK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 19 | g431.t1 | Gene3D | G3DSA:3.40.50.720 | - | 1 | 75 | 1.8E-20 |
| 18 | g431.t1 | Gene3D | G3DSA:3.40.50.720 | - | 76 | 128 | 1.3E-8 |
| 4 | g431.t1 | PANTHER | PTHR10160:SF22 | NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL | 1 | 74 | 2.8E-167 |
| 6 | g431.t1 | PANTHER | PTHR10160 | NAD(P) TRANSHYDROGENASE | 1 | 74 | 2.8E-167 |
| 5 | g431.t1 | PANTHER | PTHR10160:SF22 | NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL | 72 | 434 | 2.8E-167 |
| 7 | g431.t1 | PANTHER | PTHR10160 | NAD(P) TRANSHYDROGENASE | 72 | 434 | 2.8E-167 |
| 3 | g431.t1 | Pfam | PF01262 | Alanine dehydrogenase/PNT, C-terminal domain | 22 | 74 | 3.3E-13 |
| 1 | g431.t1 | Pfam | PF12769 | 4TM region of pyridine nucleotide transhydrogenase, mitoch | 196 | 281 | 2.1E-29 |
| 2 | g431.t1 | Pfam | PF02233 | NAD(P) transhydrogenase beta subunit | 316 | 426 | 5.2E-27 |
| 21 | g431.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 165 | - |
| 32 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 166 | 186 | - |
| 25 | g431.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 187 | 191 | - |
| 36 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 192 | 214 | - |
| 23 | g431.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 215 | 225 | - |
| 33 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 226 | 246 | - |
| 29 | g431.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 247 | 251 | - |
| 31 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 252 | 271 | - |
| 24 | g431.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 272 | 290 | - |
| 34 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 291 | 311 | - |
| 27 | g431.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 312 | 316 | - |
| 37 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 317 | 334 | - |
| 20 | g431.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 335 | 340 | - |
| 30 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 341 | 361 | - |
| 28 | g431.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 362 | 366 | - |
| 38 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 367 | 385 | - |
| 22 | g431.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 386 | 396 | - |
| 35 | g431.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 397 | 418 | - |
| 26 | g431.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 419 | 442 | - |
| 17 | g431.t1 | SMART | SM01002 | AlaDh_PNT_C_2 | 1 | 77 | 0.0024 |
| 16 | g431.t1 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 14 | 91 | 2.23E-5 |
| 13 | g431.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 192 | 214 | - |
| 12 | g431.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 226 | 245 | - |
| 9 | g431.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 249 | 271 | - |
| 8 | g431.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 288 | 307 | - |
| 14 | g431.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 317 | 334 | - |
| 11 | g431.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 341 | 363 | - |
| 15 | g431.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 367 | 385 | - |
| 10 | g431.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 397 | 419 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K00323 (H+-translocating NAD(P) transhydrogenase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
